ABIN967400

antibody from antibodies-online

Targeting: BAX BCL2L4

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN967400

Provider

antibodies-online

Product name

anti-BCL2-Associated X Protein (BAX) (AA 43-61) antibody

Antibody type

Polyclonal

Antigen

Human Bax synthetic peptide

Description

Purified from antiserum by negative adsorption and affinity chromatography.

Reactivity

Human

Host

Rabbit

Epitope

AA 43-61

Vial size

0.1 mL

Storage

4°C

References

Submitted references

Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma.

Krajewski S, Blomqvist C, Franssila K, Krajewska M, Wasenius VM, Niskanen E, Nordling S, Reed JC
Cancer research 1995 Oct 1;55(19):4471-8

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Immunoblot analysis of cellular expression of Bcl-2 family proteins, Bcl-2, Bax, Bcl-X and Mcl-1, in human peripheral blood and lymphoid tissues.

Ohta K, Iwai K, Kasahara Y, Taniguchi N, Krajewski S, Reed JC, Miyawaki T
International immunology 1995 Nov;7(11):1817-25

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BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

Yin XM, Oltvai ZN, Korsmeyer SJ
Nature 1994 May 26;369(6478):321-3

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Bcl-2 and the regulation of programmed cell death.

Reed JC
The Journal of cell biology 1994 Jan;124(1-2):1-6

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Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2.

Krajewski S, Krajewska M, Shabaik A, Miyashita T, Wang HG, Reed JC
The American journal of pathology 1994 Dec;145(6):1323-36

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death.

Oltvai ZN, Milliman CL, Korsmeyer SJ
Cell 1993 Aug 27;74(4):609-19