BS1942

CEBPB antibody from Bioworld Technology, Inc
C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5

Antibody data

Product number
BS1942
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1942, RRID:AB_1663220
Product name
C/EBP ÉÇ (V259) polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS1942
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 220-270 of Human C/EBP-ÉÇ.
Description
C/EBP ÉÇ is a member of the C/EBP transcription factor family. The C/EBP ÉÇ gene encodes several isoforms, which have truncated transcription activation domains by the alternative translational initiation at multipe AUG start sites. Initiation of translation at the in-frame AUGs forms four C/EBP ÉÇ isoforms. C/EBP ÉÇ is also known as interleukin 6-dependent DNA-binding protein (IL6DBP), liver activator protein(LAP) or liver-enriched transcriptional activator protein transcription factor 5 (TCF5). C/EBP ÉÇ contributes to the regulation of the acute phase response in hepatocytes. Stat3 has an important function in IL-6-mediated transcription of the C/EBP ÉÇ gene that has direct implication for acute phase response in liver cells.The 35 kDa C/EBP ÉÇ form requires phosphorylation for its DNA binding ability, and increased binding of C/EBP ÉÇ isoforms during acute-phase reaction occurs through its upregulation and structural modification.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -