BS4029
antibody from Bioworld Technology, Inc
Targeting: CEBPB
C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS4029 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- C/EBP ÉÇ (phospho T235/188) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic phosphopeptide derived from human C/EBP-ÉÇ around the phosphorylation site of Threonine 235.
- Description
- C/EBP ÉÇ is a member of the C/EBP transcription factor family. The C/EBP ÉÇ gene encodes several isoforms, which have truncated transcription activation domains by the alternative translational initiation at multipe AUG start sites. Initiation of translation at the in-frame AUGs forms four C/EBP ÉÇ isoforms. C/EBP ÉÇ is also known as interleukin 6-dependent DNA-binding protein (IL6DBP), liver activator protein(LAP) or liver-enriched transcriptional activator protein transcription factor 5 (TCF5). C/EBP ÉÇ contributes to the regulation of the acute phase response in hepatocytes. Stat3 has an important function in IL-6-mediated transcription of the C/EBP ÉÇ gene that has direct implication for acute phase response in liver cells.The 35 kDa C/EBP ÉÇ form requires phosphorylation for its DNA binding ability, and increased binding of C/EBP ÉÇ isoforms during acute-phase reaction occurs through its upregulation and structural modification.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of p-C/EBP-¦Â (T235/188) pAb at 1:500 dilutionLane1:HEK293T cell lysate treated with insulinLane2:DLD cell lysate