Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362966 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 396-400) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around AA 396-400 (P-I-Y-D-E) derived from Human p62Dok. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- AA 396-400
- Isotype
- IgG
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation.
Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt.
Simoncic PD, Bourdeau A, Lee-Loy A, Rohrschneider LR, Tremblay ML, Stanley ER, McGlade CJ
Molecular and cellular biology 2006 Jun;26(11):4149-60
Molecular and cellular biology 2006 Jun;26(11):4149-60
Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt.
Wick MJ, Dong LQ, Hu D, Langlais P, Liu F
The Journal of biological chemistry 2001 Nov 16;276(46):42843-50
The Journal of biological chemistry 2001 Nov 16;276(46):42843-50
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