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- Product number
- ABIN2841833 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 9-39), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 9-39, N-Term
- Antibody clone number
- RB1759-RB1760
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors.
Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling.
Evidence that Llck-mediated phosphorylation of p56dok and p62dok may play a role in CD2 signaling.
Molecular cloning of a truncated p62Dok1 isoform, p22Dok(del).
Dok1 encoding p62(dok) maps to mouse chromosome 6 and human chromosome 2 in a region of translocation in chronic lymphocytic leukemia.
Yamakawa N, Tsuchida K, Sugino H
The EMBO journal 2002 Apr 2;21(7):1684-94
The EMBO journal 2002 Apr 2;21(7):1684-94
Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling.
Liang X, Wisniewski D, Strife A, Shivakrupa, Clarkson B, Resh MD
The Journal of biological chemistry 2002 Apr 19;277(16):13732-8
The Journal of biological chemistry 2002 Apr 19;277(16):13732-8
Evidence that Llck-mediated phosphorylation of p56dok and p62dok may play a role in CD2 signaling.
Némorin JG, Duplay P
The Journal of biological chemistry 2000 May 12;275(19):14590-7
The Journal of biological chemistry 2000 May 12;275(19):14590-7
Molecular cloning of a truncated p62Dok1 isoform, p22Dok(del).
Hubert P, Ferreira V, Debre P, Bismuth G
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2000 Jun;27(3):145-8
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2000 Jun;27(3):145-8
Dok1 encoding p62(dok) maps to mouse chromosome 6 and human chromosome 2 in a region of translocation in chronic lymphocytic leukemia.
Nelms K, Snow AJ, Noben-Trauth K
Genomics 1998 Oct 15;53(2):243-5
Genomics 1998 Oct 15;53(2):243-5
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Supportive validation
- Submitted by
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- Experimental details
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