ABIN197539

antibody from antibodies-online

Targeting: DOK1 p62dok

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN197539

Provider

antibodies-online

Product name

anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (Tyr398) antibody

Antibody type

Polyclonal

Description

Affinity chromatography

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Tyr398

Vial size

50 μL

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation.

Simoncic PD, Bourdeau A, Lee-Loy A, Rohrschneider LR, Tremblay ML, Stanley ER, McGlade CJ
Molecular and cellular biology 2006 Jun;26(11):4149-60

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Sphingosine 1-phosphate receptors regulate chemokine-driven transendothelial migration of lymph node but not splenic T cells.

Yopp AC, Ochando JC, Mao M, Ledgerwood L, Ding Y, Bromberg JS
Journal of immunology (Baltimore, Md. : 1950) 2005 Sep 1;175(5):2913-24

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The role of protein tyrosine phosphatase 1B in Ras signaling.

Dubé N, Cheng A, Tremblay ML
Proceedings of the National Academy of Sciences of the United States of America 2004 Feb 17;101(7):1834-9

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Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt.

Wick MJ, Dong LQ, Hu D, Langlais P, Liu F
The Journal of biological chemistry 2001 Nov 16;276(46):42843-50