ABIN966765

antibody from antibodies-online

Targeting: DOK1 p62dok

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966765

Provider

antibodies-online

Product name

anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (pTyr398) antibody

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human p62Dok around the phosphorylation site of tyrosine 398 (E-G-YP-E-L).

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

100ug

Concentration

100ug/100ul.

Storage

Store at -20°C/1 year.

References

Submitted references

T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation.

Simoncic PD, Bourdeau A, Lee-Loy A, Rohrschneider LR, Tremblay ML, Stanley ER, McGlade CJ
Molecular and cellular biology 2006 Jun;26(11):4149-60

---

Sphingosine 1-phosphate receptors regulate chemokine-driven transendothelial migration of lymph node but not splenic T cells.

Yopp AC, Ochando JC, Mao M, Ledgerwood L, Ding Y, Bromberg JS
Journal of immunology (Baltimore, Md. : 1950) 2005 Sep 1;175(5):2913-24

---

Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt.

Wick MJ, Dong LQ, Hu D, Langlais P, Liu F
The Journal of biological chemistry 2001 Nov 16;276(46):42843-50