Ab102232

antibody from Aladdin Scientific

Targeting: MAPK1 ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2

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Validation data

Product number: Ab102232 - Provider product page
Provider: Aladdin Scientific
Product name: ERK2 Mouse mAb
Antibody type: Monoclonal
Description: Mouse anti Human ERK2 Antibody, Monoclonal antibody (D17), could be used for WB and so on.Application:WB: 0.2-2µg/mLProtein FunctionInvolved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
Reactivity: Mouse, Rat, Porcine
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: AA 25-360
Antibody clone number: D17
Vial size: 100_l,10_l,1ml,20_l,50_l
Concentration: Lot by Lot
Storage: Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

MAPK1 protein structure - Ab102232 shown in red.