PA1049
antibody from Boster Biological Technology
Targeting: MAPK1
ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2
Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- PA1049 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-MAPK1/3 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for ERK2/MAPK1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. ERK2/MAPK1 information: Molecular Weight: 41390 MW; Subcellular Localization: Cytoplasm, cytoskeleton, spindle . Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Associated with the spindle during prometaphase and metaphase (By similarity). PEA15- binding and phosphorylated DAPK1 promote its cytoplasmic retention. Phosphorylation at Ser- 246 and Ser-248 as well as autophosphorylation at Thr-190 promote nuclear localization.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Molecular Mechanisms Associated with Protecting IEC-6 Cells from Acrylamide-Induced Tight Junction Damage by Ganoderma atrum Polysaccharide.
The potential role of stromal cell-derived factor-1α/CXCR4/CXCR7 axis in adipose-derived mesenchymal stem cells.
Propionate relieves pentylenetetrazol-induced seizures, consequent mitochondrial disruption, neuron necrosis and neurological deficits in mice.
Andrographolide Inhibits Inflammatory Cytokines Secretion in LPS-Stimulated RAW264.7 Cells through Suppression of NF-κB/MAPK Signaling Pathway.
Autophagy suppresses isoprenaline-induced M2 macrophage polarization via the ROS/ERK and mTOR signaling pathway.
Hyperthermia induced HIF-1a expression of lung cancer through AKT and ERK signaling pathways.
Fructus phyllanthi tannin fraction induces apoptosis and inhibits migration and invasion of human lung squamous carcinoma cells in vitro via MAPK/MMP pathways.
Recombinant human kallistatin inhibits angiogenesis by blocking VEGF signaling pathway.
Nitric oxide inhibits gastric cancer cell growth through the modulation of the Akt pathway.
Treatment of atherosclerosis by transplantation of bone endothelial progenitor cells over-expressed paraoxonase-1 gene by recombinant adeno-associated virus in rat.
Lu J, Yang Y, Varga E, Marko D, Yu Q, Xie J, Li C, Chen Y
Molecular nutrition & food research 2023 Mar;67(6):e2200774
Molecular nutrition & food research 2023 Mar;67(6):e2200774
The potential role of stromal cell-derived factor-1α/CXCR4/CXCR7 axis in adipose-derived mesenchymal stem cells.
Ji F, Wang Y, Yuan J, Wu Q, Wang J, Liu D
Journal of cellular physiology 2020 Apr;235(4):3548-3557
Journal of cellular physiology 2020 Apr;235(4):3548-3557
Propionate relieves pentylenetetrazol-induced seizures, consequent mitochondrial disruption, neuron necrosis and neurological deficits in mice.
Cheng Y, Mai Q, Zeng X, Wang H, Xiao Y, Tang L, Li J, Zhang Y, Ding H
Biochemical pharmacology 2019 Nov;169:113607
Biochemical pharmacology 2019 Nov;169:113607
Andrographolide Inhibits Inflammatory Cytokines Secretion in LPS-Stimulated RAW264.7 Cells through Suppression of NF-κB/MAPK Signaling Pathway.
Li Y, He S, Tang J, Ding N, Chu X, Cheng L, Ding X, Liang T, Feng S, Rahman SU, Wang X, Wu J
Evidence-based complementary and alternative medicine : eCAM 2017;2017:8248142
Evidence-based complementary and alternative medicine : eCAM 2017;2017:8248142
Autophagy suppresses isoprenaline-induced M2 macrophage polarization via the ROS/ERK and mTOR signaling pathway.
Shan M, Qin J, Jin F, Han X, Guan H, Li X, Zhang J, Zhang H, Wang Y
Free radical biology & medicine 2017 Sep;110:432-443
Free radical biology & medicine 2017 Sep;110:432-443
Hyperthermia induced HIF-1a expression of lung cancer through AKT and ERK signaling pathways.
Wan J, Wu W
Journal of experimental & clinical cancer research : CR 2016 Jul 26;35(1):119
Journal of experimental & clinical cancer research : CR 2016 Jul 26;35(1):119
Fructus phyllanthi tannin fraction induces apoptosis and inhibits migration and invasion of human lung squamous carcinoma cells in vitro via MAPK/MMP pathways.
Zhao HJ, Liu T, Mao X, Han SX, Liang RX, Hui LQ, Cao CY, You Y, Zhang LZ
Acta pharmacologica Sinica 2015 Jun;36(6):758-68
Acta pharmacologica Sinica 2015 Jun;36(6):758-68
Recombinant human kallistatin inhibits angiogenesis by blocking VEGF signaling pathway.
Huang KF, Yang HY, Xing YM, Lin JS, Diao Y
Journal of cellular biochemistry 2014 Mar;115(3):575-84
Journal of cellular biochemistry 2014 Mar;115(3):575-84
Nitric oxide inhibits gastric cancer cell growth through the modulation of the Akt pathway.
Sang J, Chen Y, Tao Y
Molecular medicine reports 2011 Nov-Dec;4(6):1163-7
Molecular medicine reports 2011 Nov-Dec;4(6):1163-7
Treatment of atherosclerosis by transplantation of bone endothelial progenitor cells over-expressed paraoxonase-1 gene by recombinant adeno-associated virus in rat.
Wang F, Xue J, Wang D, Wang X, Lu S, Tan M
Biological & pharmaceutical bulletin 2010;33(11):1806-13
Biological & pharmaceutical bulletin 2010;33(11):1806-13
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-MAPK1/3 antibody, PA1049, Western blottingWB: HELA Cell Lysate
- Additional image