Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- PAB1714 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB1714, RRID:AB_1238072
- Product name
- HDAC6 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of HDAC6.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes.
Three proteins define a class of human histone deacetylases related to yeast Hda1p.
Transcriptional control. Sinful repression.
Hook SS, Orian A, Cowley SM, Eisenman RN
Proceedings of the National Academy of Sciences of the United States of America 2002 Oct 15;99(21):13425-30
Proceedings of the National Academy of Sciences of the United States of America 2002 Oct 15;99(21):13425-30
Three proteins define a class of human histone deacetylases related to yeast Hda1p.
Grozinger CM, Hassig CA, Schreiber SL
Proceedings of the National Academy of Sciences of the United States of America 1999 Apr 27;96(9):4868-73
Proceedings of the National Academy of Sciences of the United States of America 1999 Apr 27;96(9):4868-73
Transcriptional control. Sinful repression.
Wolffe AP
Nature 1997 May 1;387(6628):16-7
Nature 1997 May 1;387(6628):16-7
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The HDAC6 polyclonal antibody (Cat # PAB1714) is used in Western blot to detect HDAC6 in mouse kidney tissue lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma reacted with HDAC6 polyclonal antibody (Cat # PAB1714) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)