HPA001185

antibody from Atlas Antibodies

Targeting: TASL CXorf21, FLJ11577

Western blot (Data presented on provider website)

Antibody Data

Product number

HPA001185

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA001185, RRID:AB_1078591

Product name

Anti-CXorf21

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human CXorf21, Gene description: chromosome X open reading frame 21, Alternative Gene Names: FLJ11577, Validated applications: WB, Uniprot ID: Q9HAI6, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity

Boeszoermenyi A, Bernaleau L, Chen X, Kartnig F, Xie M, Zhang H, Zhang S, Delacrétaz M, Koren A, Hopp A, Dvorak V, Kubicek S, Aletaha D, Yang M, Rebsamen M, Heinz L, Superti-Furga G
Nature Communications 2023;14(1)

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Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling

Chen X, Xie M, Zhang S, Monguió-Tortajada M, Yin J, Liu C, Zhang Y, Delacrétaz M, Song M, Wang Y, Dong L, Ding Q, Zhou B, Tian X, Deng H, Xu L, Liu X, Yang Z, Chang Q, Na J, Zeng W, Superti-Furga G, Rebsamen M, Yang M
Nature Communications 2023;14(1)

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TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9

Heinz L, Lee J, Kapoor U, Kartnig F, Sedlyarov V, Papakostas K, César-Razquin A, Essletzbichler P, Goldmann U, Stefanovic A, Bigenzahn J, Scorzoni S, Pizzagalli M, Bensimon A, Müller A, King F, Li J, Girardi E, Mbow M, Whitehurst C, Rebsamen M, Superti-Furga G
Nature 2020;581(7808):316-322

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Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus.

Odhams CA, Roberts AL, Vester SK, Duarte CST, Beales CT, Clarke AJ, Lindinger S, Daffern SJ, Zito A, Chen L, Jones LL, Boteva L, Morris DL, Small KS, Fernando MMA, Cunninghame Graham DS, Vyse TJ
Nature communications 2019 May 15;10(1):2164