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Learn19698-1-AP
antibody from Proteintech Group
Targeting: LAMC2
BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 19698-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19698-1-AP, RRID:AB_10644139
- Product name
- LAMC2 antibody
- Antibody type
- Polyclonal
- Description
- LAMC2 antibody (Cat. #19698-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references LAMC2 Drives Airway Remodeling in COPD via EMT Regulation Through the AKT Pathway.
Single-cell and bulk transcriptomics reveal Fusobacterium nucleatum promotes colorectal cancer metastasis by upregulating LAMC2 in in vitro and in vivo models.
A Genome-Wide Synthetic Lethal Screen Identifies Spermidine Synthase as a Target to Enhance Erdafitinib Efficacy in FGFR-Mutant Bladder Cancer.
miR-212-5p Regulates PM(2.5)-Induced Apoptosis by Targeting LAMC2 and LAMA3.
The anti-cancer mechanism of Celastrol by targeting JAK2/STAT3 signaling pathway in gastric and ovarian cancer.
Hypoxia promotes histone H3K9 lactylation to enhance LAMC2 transcription in esophageal squamous cell carcinoma.
Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction.
Migration-inducing gene-7 promotes glioma cell proliferation and invasiveness via activating the MAPK signaling pathway.
Connexins orchestrate progression of breast cancer metastasis to the brain by promoting FAK activation.
Laminin‑332 mediates proliferation, apoptosis, invasion, migration and epithelial‑to‑mesenchymal transition in pancreatic ductal adenocarcinoma.
Proteomic analysis reveals the protective effects of emodin on severe acute pancreatitis induced lung injury by inhibiting neutrophil proteases activity.
The Notch pathway mediates the angiotensin II-induced synthesis of extracellular matrix components in podocytes.
Wang Z, Shi J, Zhang Y, Luo Y, Rao Y, Qu J, Gai X, Sun Y
International journal of chronic obstructive pulmonary disease 2026;21:580964
International journal of chronic obstructive pulmonary disease 2026;21:580964
Single-cell and bulk transcriptomics reveal Fusobacterium nucleatum promotes colorectal cancer metastasis by upregulating LAMC2 in in vitro and in vivo models.
Ran S, Ye J, Wang H, Liu F, Ou S, Chen Z, Song Y, Liu SL, Huang R
Scientific reports 2025 Nov 26;15(1):42100
Scientific reports 2025 Nov 26;15(1):42100
A Genome-Wide Synthetic Lethal Screen Identifies Spermidine Synthase as a Target to Enhance Erdafitinib Efficacy in FGFR-Mutant Bladder Cancer.
Yu Y, Gao X, Zhao H, Sun J, Wang M, Xiong X, Li J, Huang C, Zhang H, Jiang G, Xiao X
Cancer research 2025 Jun 16;85(12):2288-2301
Cancer research 2025 Jun 16;85(12):2288-2301
miR-212-5p Regulates PM(2.5)-Induced Apoptosis by Targeting LAMC2 and LAMA3.
Jia Y, Zhang X, Zhao C, Ma Z, Sun K, Sun Y, Du X, Liu M, Liang X, Yu X, Gao Y
International journal of molecular sciences 2025 Feb 19;26(4)
International journal of molecular sciences 2025 Feb 19;26(4)
The anti-cancer mechanism of Celastrol by targeting JAK2/STAT3 signaling pathway in gastric and ovarian cancer.
Wu K, Qiu C, Ma Q, Chen F, Lu T
Toxicology and applied pharmacology 2024 Oct;491:117077
Toxicology and applied pharmacology 2024 Oct;491:117077
Hypoxia promotes histone H3K9 lactylation to enhance LAMC2 transcription in esophageal squamous cell carcinoma.
Zang Y, Wang A, Zhang J, Xia M, Jiang Z, Jia B, Lu C, Chen C, Wang S, Zhang Y, Wang C, Cao X, Niu Z, He C, Bai X, Tian S, Zhai G, Cao H, Chen Y, Zhang K
iScience 2024 Jul 19;27(7):110188
iScience 2024 Jul 19;27(7):110188
Endothelium-specific deletion of p62 causes organ fibrosis and cardiac dysfunction.
Feng J, Li Y, Zhang Y, Sun S, Sun J, Xu Q, Ji X, Liu Y, Wan Q
Journal of translational medicine 2024 Feb 16;22(1):161
Journal of translational medicine 2024 Feb 16;22(1):161
Migration-inducing gene-7 promotes glioma cell proliferation and invasiveness via activating the MAPK signaling pathway.
Pan Z, Chen C, Huang X, Xiong Y, Kang X, Zhou J, Guo X, Zheng S, Wang C, Zheng F, Hu W
Neoplasma 2023 Aug;70(4):534-544
Neoplasma 2023 Aug;70(4):534-544
Connexins orchestrate progression of breast cancer metastasis to the brain by promoting FAK activation.
Lorusso G, Wyss CB, Kuonen F, Vannini N, Billottet C, Duffey N, Pineau R, Lan Q, Wirapati P, Barras D, Tancredi A, Lyck R, Lehr HA, Engelhardt B, Delorenzi M, Bikfalvi A, Rüegg C
Science translational medicine 2022 Sep 7;14(661):eaax8933
Science translational medicine 2022 Sep 7;14(661):eaax8933
Laminin‑332 mediates proliferation, apoptosis, invasion, migration and epithelial‑to‑mesenchymal transition in pancreatic ductal adenocarcinoma.
Huang C, Chen J
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Proteomic analysis reveals the protective effects of emodin on severe acute pancreatitis induced lung injury by inhibiting neutrophil proteases activity.
Xu C, Zhang J, Liu J, Li Z, Liu Z, Luo Y, Xu Q, Wang M, Zhang G, Wang F, Chen H
Journal of proteomics 2020 May 30;220:103760
Journal of proteomics 2020 May 30;220:103760
The Notch pathway mediates the angiotensin II-induced synthesis of extracellular matrix components in podocytes.
Yao M, Wang X, Wang X, Zhang T, Chi Y, Gao F
International journal of molecular medicine 2015 Jul;36(1):294-300
International journal of molecular medicine 2015 Jul;36(1):294-300
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LAMC2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human LAMC2. This antibody recognizes human, mouse, rat antigen. The LAMC2 antibody has been validated for the following applications: ELISA, WB analysis.
