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- References [16]
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- Product number
- 17086-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17086-1-AP, RRID:AB_2161289
- Product name
- PDPK1 antibody
- Antibody type
- Polyclonal
- Description
- PDPK1 antibody (Cat. #17086-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FBXW7 Targets the SPT6-ΔNp63 Axis for Degradation to Inhibit Esophageal Tumorigenesis Induced by 4-Nitroquinoline N-Oxide.
IGF2BP2 regulates gastric cancer radiotherapy resistance through HIF1α-mediated glycolysis.
PDPK1 governs macrophage M2 polarization via hypoxia-driven CD47/AKT-glycolytic Axis in endometriosis.
A novel peptide PDHK1-241aa encoded by circPDHK1 promotes ccRCC progression via interacting with PPP1CA to inhibit AKT dephosphorylation and activate the AKT-mTOR signaling pathway.
In Vitro and Vivo Experiments Revealing Astragalin Inhibited Lung Adenocarcinoma Development via LINC00582/miR-140-3P/PDPK1.
Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.
Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery.
HIF-1α Mediates Arsenic-Induced Metabolic Reprogramming in Lung Bronchial Epithelial Cells.
Activation of long-non-coding RNA NEAT1 sponging microRNA-147 inhibits radiation damage by targeting PDPK1 in troxerutin radioprotection.
WDR54 exerts oncogenic roles in T-cell acute lymphoblastic leukemia.
Identification of senescence-related subtypes, establishment of a prognosis model, and characterization of a tumor microenvironment infiltration in breast cancer.
Redox sensor NPGPx restrains ZAP70 activity and modulates T cell homeostasis.
LncRNA CAR10 Upregulates PDPK1 to Promote Cervical Cancer Development by Sponging miR-125b-5p.
A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade.
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
Transfection with GLS2 Glutaminase (GAB) Sensitizes Human Glioblastoma Cell Lines to Oxidative Stress by a Common Mechanism Involving Suppression of the PI3K/AKT Pathway.
Zhang J, Yin L, You X, Xiong X, Sun Y
MedComm 2026 Mar;7(3):e70662
MedComm 2026 Mar;7(3):e70662
IGF2BP2 regulates gastric cancer radiotherapy resistance through HIF1α-mediated glycolysis.
Zhang Q, Liu X, Chen Y, Wang R, Zhao S, Tian Y, Li S, Liu X
Frontiers in oncology 2025;15:1512177
Frontiers in oncology 2025;15:1512177
PDPK1 governs macrophage M2 polarization via hypoxia-driven CD47/AKT-glycolytic Axis in endometriosis.
Li H, Chai X
Cellular signalling 2025 Oct;134:111922
Cellular signalling 2025 Oct;134:111922
A novel peptide PDHK1-241aa encoded by circPDHK1 promotes ccRCC progression via interacting with PPP1CA to inhibit AKT dephosphorylation and activate the AKT-mTOR signaling pathway.
Huang B, Ren J, Ma Q, Yang F, Pan X, Zhang Y, Liu Y, Wang C, Zhang D, Wei L, Ran L, Zhao H, Liang C, Wang X, Wang S, Li H, Ning H, Ran A, Li W, Wang Y, Xiao B
Molecular cancer 2024 Feb 15;23(1):34
Molecular cancer 2024 Feb 15;23(1):34
In Vitro and Vivo Experiments Revealing Astragalin Inhibited Lung Adenocarcinoma Development via LINC00582/miR-140-3P/PDPK1.
Bai J, Chen Y, Zhao G, Gui R
Journal of biochemical and molecular toxicology 2024 Dec;38(12):e70042
Journal of biochemical and molecular toxicology 2024 Dec;38(12):e70042
Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.
Gong K, Zheng Y, Liu Y, Zhang T, Song Y, Chen W, Guo L, Zhou J, Liu W, Fang T, Chen Y, Wang J, Pan F, Shi K
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3
Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery.
Liu Y, Xie X, Wang P, Luo J, Chen Y, Xu Q, Zhou J, Lu X, Zhao J, Chen Z, Zuo D
Journal of innate immunity 2023;15(1):37-49
Journal of innate immunity 2023;15(1):37-49
HIF-1α Mediates Arsenic-Induced Metabolic Reprogramming in Lung Bronchial Epithelial Cells.
Wang W, Zhang A
Biological trace element research 2023 May;201(5):2284-2293
Biological trace element research 2023 May;201(5):2284-2293
Activation of long-non-coding RNA NEAT1 sponging microRNA-147 inhibits radiation damage by targeting PDPK1 in troxerutin radioprotection.
Hu YJ, Song GY, Zhang F, Zhang N, Wang F, Wang JL, Wang X, Wang TY, Li YF, Yan YD, Dou WT, Cheng CY, Xu P
iScience 2023 Feb 17;26(2):105932
iScience 2023 Feb 17;26(2):105932
WDR54 exerts oncogenic roles in T-cell acute lymphoblastic leukemia.
Li H, Zhang D, Fu Q, Wang S, Zhang X, Lin Z, Wang Z, Song J, Su Z, Xue V, Liu S, Chen Y, Zhou L, Zhao N, Lu D
Cancer science 2023 Aug;114(8):3318-3329
Cancer science 2023 Aug;114(8):3318-3329
Identification of senescence-related subtypes, establishment of a prognosis model, and characterization of a tumor microenvironment infiltration in breast cancer.
Zhou Y, Xiao L, Long G, Cao J, Liu S, Tao Y, Zhou L, Tang J
Frontiers in immunology 2022;13:921182
Frontiers in immunology 2022;13:921182
Redox sensor NPGPx restrains ZAP70 activity and modulates T cell homeostasis.
Su FY, Huang SC, Wei PC, Hsu PH, Li JP, Su LW, Hsieh YL, Hu CM, Hsu JL, Yang CY, Chung CY, Shew JY, Lan JL, Sytwu HK, Lee EY, Lee WH
Free radical biology & medicine 2021 Mar;165:368-384
Free radical biology & medicine 2021 Mar;165:368-384
LncRNA CAR10 Upregulates PDPK1 to Promote Cervical Cancer Development by Sponging miR-125b-5p.
Hu T, Zhang Q, Gao L
BioMed research international 2020;2020:4351671
BioMed research international 2020;2020:4351671
A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade.
Yang ZH, Wu XN, He P, Wang X, Wu J, Ai T, Zhong CQ, Wu X, Cong Y, Zhu R, Li H, Cai ZY, Mo W, Han J
Molecular cell 2020 Oct 15;80(2):296-310.e6
Molecular cell 2020 Oct 15;80(2):296-310.e6
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
He X, Li M, Yu H, Liu G, Wang N, Yin C, Tu Q, Narla G, Tao Y, Cheng S, Yin H
PLoS biology 2020 Dec;18(12):e3000803
PLoS biology 2020 Dec;18(12):e3000803
Transfection with GLS2 Glutaminase (GAB) Sensitizes Human Glioblastoma Cell Lines to Oxidative Stress by a Common Mechanism Involving Suppression of the PI3K/AKT Pathway.
Majewska E, Márquez J, Albrecht J, Szeliga M
Cancers 2019 Jan 19;11(1)
Cancers 2019 Jan 19;11(1)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PDPK1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PDPK1. This antibody recognizes human, mouse, rat antigen. The PDPK1 antibody has been validated for the following applications: ELISA, WB analysis.
