Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 17086-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17086-1-AP, RRID:AB_2161289
- Product name
- PDPK1 antibody
- Antibody type
- Polyclonal
- Description
- PDPK1 antibody (Cat. #17086-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Redox sensor NPGPx restrains ZAP70 activity and modulates T cell homeostasis.
LncRNA CAR10 Upregulates PDPK1 to Promote Cervical Cancer Development by Sponging miR-125b-5p.
A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade.
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
Transfection with GLS2 Glutaminase (GAB) Sensitizes Human Glioblastoma Cell Lines to Oxidative Stress by a Common Mechanism Involving Suppression of the PI3K/AKT Pathway.
Su FY, Huang SC, Wei PC, Hsu PH, Li JP, Su LW, Hsieh YL, Hu CM, Hsu JL, Yang CY, Chung CY, Shew JY, Lan JL, Sytwu HK, Lee EY, Lee WH
Free radical biology & medicine 2021 Mar;165:368-384
Free radical biology & medicine 2021 Mar;165:368-384
LncRNA CAR10 Upregulates PDPK1 to Promote Cervical Cancer Development by Sponging miR-125b-5p.
Hu T, Zhang Q, Gao L
BioMed research international 2020;2020:4351671
BioMed research international 2020;2020:4351671
A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade.
Yang ZH, Wu XN, He P, Wang X, Wu J, Ai T, Zhong CQ, Wu X, Cong Y, Zhu R, Li H, Cai ZY, Mo W, Han J
Molecular cell 2020 Oct 15;80(2):296-310.e6
Molecular cell 2020 Oct 15;80(2):296-310.e6
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
He X, Li M, Yu H, Liu G, Wang N, Yin C, Tu Q, Narla G, Tao Y, Cheng S, Yin H
PLoS biology 2020 Dec;18(12):e3000803
PLoS biology 2020 Dec;18(12):e3000803
Transfection with GLS2 Glutaminase (GAB) Sensitizes Human Glioblastoma Cell Lines to Oxidative Stress by a Common Mechanism Involving Suppression of the PI3K/AKT Pathway.
Majewska E, Márquez J, Albrecht J, Szeliga M
Cancers 2019 Jan 19;11(1)
Cancers 2019 Jan 19;11(1)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The PDPK1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PDPK1. This antibody recognizes human, mouse, rat antigen. The PDPK1 antibody has been validated for the following applications: ELISA, WB analysis.