ABIN966816

antibody from antibodies-online

Targeting: PDPK1 PDK1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966816

Provider

antibodies-online

Product name

anti-3-phosphoinositide Dependent Protein Kinase-1 (PDPK1) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized non-phosphopeptide derived from human PDK1 around the phosphorylation site of serine 241(A-N-SP-F-V).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation.

Scheid MP, Parsons M, Woodgett JR
Molecular and cellular biology 2005 Mar;25(6):2347-63

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Large-scale characterization of HeLa cell nuclear phosphoproteins.

Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 17;101(33):12130-5

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Nuclear translocation of 3'-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function.

Lim MA, Kikani CK, Wick MJ, Dong LQ
Proceedings of the National Academy of Sciences of the United States of America 2003 Nov 25;100(24):14006-11

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Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3.

Sato S, Fujita N, Tsuruo T
The Journal of biological chemistry 2002 Oct 18;277(42):39360-7

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Insulin stimulates increased catalytic activity of phosphoinositide-dependent kinase-1 by a phosphorylation-dependent mechanism.

Chen H, Nystrom FH, Dong LQ, Li Y, Song S, Liu F, Quon MJ
Biochemistry 2001 Oct 2;40(39):11851-9