27592-1-AP

antibody from Proteintech Group

Targeting: RACK1 Gnb2-rs1, GNB2L1, H12.3

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

27592-1-AP

Provider

Proteintech Group

Product name

RACK1; GNB2L1 antibody

Antibody type

Polyclonal

Description

RACK1; GNB2L1 antibody (Cat. #27592-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Oncogenic and immunological roles of LAMP5 across cancers and its potential utility in bladder cancer.

Lin Z, Zhao K, Wang S, Liu J, Liu Y, Qiang K, Huang M, Sun N, Zhang P, Hu Y, Lu Y, Jin H
Apoptosis : an international journal on programmed cell death 2026 Feb 9;31(2):65

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OTUD1 deficiency attenuates myocardial ischemia/reperfusion induced cardiomyocyte apoptosis by regulating RACK1 phosphorylation.

Luo Y, Li WX, Zheng QS, Yan JQ, Yang YD, Shen SR, Zhang QH, Liang G, Wang Y, Chen DD, Hu X, Luo W
Acta pharmacologica Sinica 2025 Oct;46(10):2649-2662

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Characterization of ribosome heterogeneity during endothelial to hematopoietic transition.

Tian X, Liu D, Liu B, Lan Y, Zhou J
FEBS open bio 2025 Oct;15(10):1658-1666

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RPL6 Interacts with HMGCS1 to Stabilize HIF-1α by Promoting Cholesterol Production in Hepatocellular Carcinoma.

Yang M, Cheng S, Gu H, Zhong S, Zhang D, He X, Chen W, Deng H, Ren J, Chen P, Tan M, Zhang H, Li F, Zhang Z, Hu Y, Chen J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e01373

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Hypoxia-induced degradation of FTO promotes apoptosis by unmasking RACK1-mediated activation of MTK1-JNK1/2 pathway.

Li C, Liu Z, Fu C, Li H, He T, Wu G, Sheng Y, Shen M, Liu H
Journal of advanced research 2025 Nov;77:137-153

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Modification of RNF183 via m6A Methylation Mediates Podocyte Dysfunction in Diabetic Nephropathy by Regulating PKM2 Ubiquitination and Degradation.

Guo D, Pang Y, Wang W, Feng Y, Wang L, Sun Y, Hao J, Li F, Zhao S
Cells 2025 Mar 1;14(5)

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HucMSC-Ex alleviates inflammatory bowel disease by regulating O-GlcNAcylation modification of RACK1 in intestinal epithelial cells.

Liu Z, Yuan J, Din MA, Tian Y, Mao F
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114606

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Inhibitory effects of circR-127aa on gastric cancer progression and tumor growth.

Qiao L, Pan W, Yang J, Cheng Y, Han Y, Zhu Q, Liu R, Zhang H, Ba Y
Cellular signalling 2025 Jan;125:111520

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LRP11 facilitates lipid metabolism and malignancy in hepatocellular carcinoma by stabilizing RACK1 through USP5 regulation.

Liang L, Jia W, Wang J, Feng Y, Zhu D, Zhao W, Xu C, Ling X, Lv Q, Ai X, Kong L, Ding W
Molecular medicine (Cambridge, Mass.) 2025 Jan 31;31(1):35

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iTRAQ-Based Proteomic Analysis of Spontaneous Achilles Tendon Rupture.

Qianman B, Jiasharete T, Badalihan A, Mamately A, Yeerbo N, Bahesutihan Y, Wupuer A, Aisaiding A, Wuerliebieke J, Jialihasi A, Li P, Jielile J
Journal of proteome research 2025 Jan 3;24(1):65-76

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SMURF2 Inhibits Autophagy and Growth in Ovarian Cancer by Regulating the RACK1/AKT/mTOR Pathway.

Wu L, Xiao Z, Zhang S, Guo L, Liu X, Zhang L, Xu J, Lv M, Wang J
American journal of reproductive immunology (New York, N.Y. : 1989) 2025 Aug;94(2):e70140

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RACK1 Promotes Meningioma Progression by Activation of NF-κB Pathway via Preventing CSNK2B from Ubiquitination Degradation.

Maalim AA, Wang Z, Huang Y, Lei T
Cancers 2024 Feb 13;16(4)

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Circular RNA EIF3I promotes papillary thyroid cancer progression by interacting with AUF1 to increase Cyclin D1 production.

Yao X, Liu H, Wang Z, Lu F, Chen W, Feng Q, Miao Y, Zhang J, Wang Y, Chen Y, Xue L, Liu Y, Chen L, Zhang Q
Oncogene 2023 Oct;42(43):3206-3218

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The matrix protein of respiratory syncytial virus suppresses interferon signaling via RACK1 association.

Cao J, Shi M, Zhu L, Li X, Li A, Wu S-Y, Chiang C-M, Zhang Y
Journal of virology 2023 Oct 31;97(10):e0074723

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RACK1 promotes porcine reproductive and respiratory syndrome virus infection in Marc-145 cells through ERK1/2 activation.

Wang X, Bi J, Yang Y, Li L, Zhang R, Li Y, Cheng M, Li W, Yang G, Lin Y, Liu J, Yin G
Virology 2023 Nov;588:109886

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CAP2 promotes gastric cancer metastasis by mediating the interaction between tumor cells and tumor-associated macrophages.

Zhang G, Gao Z, Guo X, Ma R, Wang X, Zhou P, Li C, Tang Z, Zhao R, Gao P
The Journal of clinical investigation 2023 Nov 1;133(21)

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Protein phosphatase 2A deficiency in hippocampal CA1 inhibits priming effect of morphine on conditioned place preference in mice.

Dai J, Xie R, Sun ZN, Kou XL, Zhang JQ, Qi C, Liu R, Gao X, Wang J, Gao J
Cerebral cortex (New York, N.Y. : 1991) 2023 May 24;33(11):6594-6607

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Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development.

Shen M, Sirois CL, Guo Y, Li M, Dong Q, Méndez-Albelo NM, Gao Y, Khullar S, Kissel L, Sandoval SO, Wolkoff NE, Huang SX, Xu Z, Bryan JE, Contractor AM, Korabelnikov T, Glass IA, Doherty D, Birth Defects Research Laboratory, Levine JE, Sousa AMM, Chang Q, Bhattacharyya A, Wang D, Werling DM, Zhao X
Neuron 2023 Dec 20;111(24):3988-4005.e11

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USP41 promotes breast cancer via regulating RACK1.

Huang M, Xiao J, Yan C, Wang T, Ling R
Annals of translational medicine 2021 Oct;9(20):1566

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MIIP inhibits clear cell renal cell carcinoma proliferation and angiogenesis via negative modulation of the HIF-2α-CYR61 axis.

Yan F, Wang Q, Xia M, Ru Y, Hu W, Yan G, Xiong X, Zhang M, Wang J, Li Q, Zhang B, Wang H, Lin W, Wu G, Li X
Cancer biology & medicine 2021 Dec 22;19(6):818-35

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Small molecule screening identified cepharanthine as an inhibitor of porcine reproductive and respiratory syndrome virus infection in vitro by suppressing integrins/ILK/RACK1/PKCα/NF-κB signalling axis.

Yang C, Zuo Q, Liu X, Zhao Q, Pu H, Gao L, Zhao L, Guo Z, Lin Y, Liu J, Bi J, Yin G
Veterinary microbiology 2021 Apr;255:109016

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Integrin β3, a RACK1 interacting protein, is critical for porcine reproductive and respiratory syndrome virus infection and NF-κB activation in Marc-145 cells.

Yang C, Lan R, Wang X, Zhao Q, Li X, Bi J, Wang J, Yang G, Lin Y, Liu J, Yin G
Virus research 2020 Jun;282:197956

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Inhibition of porcine reproductive and respiratory syndrome virus by PKC inhibitor dequalinium chloride in vitro.

Liu X, Gao L, Zhao Q, Wang X, Yang C, Bi J, Yang R, Jin X, Lan R, Cui R, Wang X, Li W, Wang X, Yang Y, Yu X, Lin Y, Liu J, Yin G
Veterinary microbiology 2020 Dec;251:108913