sc-1656

antibody from Santa Cruz Biotechnology

Targeting: STAT5B

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

sc-1656

Provider

Santa Cruz Biotechnology

Proper citation

Santa Cruz Biotechnology Cat#sc-1656, RRID:AB_2197067

Product name

Anti-STAT5B

Antibody type

Monoclonal

Antigen

Synthetic peptide

Reactivity

Human

Host

Mouse

References

Submitted references

Role of ERalpha in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis.

Miermont AM, Parrish AR, Furth PA
Carcinogenesis 2010 Jun;31(6):1124-31

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Oncoproteomic analysis reveals co-upregulation of RELA and STAT5 in carboplatin resistant ovarian carcinoma.

Jinawath N, Vasoontara C, Jinawath A, Fang X, Zhao K, Yap KL, Guo T, Lee CS, Wang W, Balgley BM, Davidson B, Wang TL, Shih IeM
PloS one 2010 Jun 18;5(6):e11198

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Uremia attenuates growth hormone-stimulated insulin-like growth factor-1 expression, a process worsened by inflammation

Yu Chen, Jaclyn Biada, Sumita Sood, Ralph Rabkin
Kidney International 2010 Apr;78(1):89-95

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The 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Janus kinase 2-signal transducer and activator of transcription-5B-dependent expression of interleukin-8.

Cheranov SY, Wang D, Kundumani-Sridharan V, Karpurapu M, Zhang Q, Chava KR, Rao GN
Blood 2009 Jun 4;113(23):6023-33

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Proteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination.

Baugh JM, Viktorova EG, Pilipenko EV
Journal of molecular biology 2009 Feb 27;386(3):814-27

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Endotoxin-induced growth hormone resistance in skeletal muscle.

Chen Y, Sood S, Krishnamurthy VM, Rotwein P, Rabkin R
Endocrinology 2009 Aug;150(8):3620-6

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Human and simian immunodeficiency viruses deregulate early hematopoiesis through a Nef/PPARgamma/STAT5 signaling pathway in macaques.

Prost S, Le Dantec M, Augé S, Le Grand R, Derdouch S, Auregan G, Déglon N, Relouzat F, Aubertin AM, Maillere B, Dusanter-Fourt I, Kirszenbaum M
The Journal of clinical investigation 2008 May;118(5):1765-75

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JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells.

Jin H, Lanning NJ, Carter-Su C
Molecular endocrinology (Baltimore, Md.) 2008 Aug;22(8):1825-41

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Suppression of activation of signal transducer and activator of transcription-5B signaling in the vessel wall reduces balloon injury-induced neointima formation.

Kundumani-Sridharan V, Wang D, Karpurapu M, Liu Z, Zhang C, Dronadula N, Rao GN
The American journal of pathology 2007 Oct;171(4):1381-94

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Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity.

Hinz M, Lemke P, Anagnostopoulos I, Hacker C, Krappmann D, Mathas S, Dörken B, Zenke M, Stein H, Scheidereit C
The Journal of experimental medicine 2002 Sep 2;196(5):605-17

Immunohistochemistry

Supportive validation

Submitted by

per

Main image

Experimental details

Immunohistochemical staining of human colon shows strong cytoplasmic and nuclear positivity in glandular cells.

Validation comment

Staining pattern partly consistent with experimental and/or bioinformatic data.