Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 11401-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11401-1-AP, RRID:AB_2056316
- Product name
- Alpha Adaptin antibody
- Antibody type
- Polyclonal
- Description
- Alpha Adaptin antibody (Cat. #11401-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Five Inhibitory Receptors Display Distinct Vesicular Distributions in Murine T Cells.
ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease.
Five inhibitory receptors display distinct vesicular distributions in T cells.
Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis.
Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Ginsenoside compound-K inhibits the activity of B cells through inducing IgD-B cell receptor endocytosis in mice with collagen-induced arthritis.
Speckle-Type POZ Protein Down-Regulates Matrix Metalloproteinase 2 Expression via Sp1/PI3K/Akt Signaling Pathway in Colorectal Cancer.
Alterted SLIT2/ROBO1 signalling is linked to impaired placentation of missed and threatened miscarriage in early pregnancy.
Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b.
The ap-2 clathrin adaptor mediates endocytosis of an inhibitory killer cell Ig-like receptor in human NK cells.
Lu J, Veler A, Simonetti B, Raj T, Chou PH, Cross SJ, Phillips AM, Ruan X, Huynh L, Dowsey AW, Ye D, Murphy RF, Verkade P, Cullen PJ, Wülfing C
Cells 2023 Oct 31;12(21)
Cells 2023 Oct 31;12(21)
ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease.
Bartosch AMW, Youth EHH, Hansen S, Kaufman ME, Xiao H, Koo SY, Ashok A, Sivakumar S, Soni RK, Dumitrescu LC, Lam TG, Ropri AS, Lee AJ, Klein HU, Vardarajan BN, Bennett DA, Young-Pearse TL, De Jager PL, Hohman TJ, Sproul AA, Teich AF
bioRxiv : the preprint server for biology 2023 Mar 21;
bioRxiv : the preprint server for biology 2023 Mar 21;
Five inhibitory receptors display distinct vesicular distributions in T cells.
Lu J, Veler A, Simonetti B, Raj T, Chou PH, Cross SJ, Phillips AM, Ruan X, Huynh L, Dowsey AW, Ye D, Murphy RF, Verkade P, Cullen PJ, Wülfing C
bioRxiv : the preprint server for biology 2023 Jul 25;
bioRxiv : the preprint server for biology 2023 Jul 25;
Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis.
Heaton GR, Landeck N, Mamais A, Nalls MA, Nixon-Abell J, Kumaran R, Beilina A, Pellegrini L, Li Y, International Parkinson Disease Genomics Consortium (IPDGC), Harvey K, Cookson MR
Neurobiology of disease 2020 Jul;141:104948
Neurobiology of disease 2020 Jul;141:104948
Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Simonetti B, Paul B, Chaudhari K, Weeratunga S, Steinberg F, Gorla M, Heesom KJ, Bashaw GJ, Collins BM, Cullen PJ
Nature cell biology 2019 Oct;21(10):1219-1233
Nature cell biology 2019 Oct;21(10):1219-1233
Ginsenoside compound-K inhibits the activity of B cells through inducing IgD-B cell receptor endocytosis in mice with collagen-induced arthritis.
Zhang M, Hu S, Tao J, Zhou W, Wang R, Tai Y, Xiao F, Wang Q, Wei W
Inflammopharmacology 2019 Aug;27(4):845-856
Inflammopharmacology 2019 Aug;27(4):845-856
Speckle-Type POZ Protein Down-Regulates Matrix Metalloproteinase 2 Expression via Sp1/PI3K/Akt Signaling Pathway in Colorectal Cancer.
Zhang S, Xiao J, Chai Y, Hong Z, Liu Z, Yuan R, Luo Z, Zhou X, Lucero-Prisno DE III, Huang K
Digestive diseases and sciences 2018 Feb;63(2):395-402
Digestive diseases and sciences 2018 Feb;63(2):395-402
Alterted SLIT2/ROBO1 signalling is linked to impaired placentation of missed and threatened miscarriage in early pregnancy.
Li P, Shi Y, Shuai H, Cai Y, Lu W, Wang G, Gao L, Wang L, Fan X, Yang X
Histopathology 2017 Oct;71(4):543-552
Histopathology 2017 Oct;71(4):543-552
Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b.
Shao X, Liu Y, Yu Q, Ding Z, Qian W, Zhang L, Zhang J, Jiang N, Gui L, Xu Z, Hong Y, Ma Y, Wei Y, Liu X, Jiang C, Zhu M, Li H, Li H
Cell research 2016 May;26(5):593-612
Cell research 2016 May;26(5):593-612
The ap-2 clathrin adaptor mediates endocytosis of an inhibitory killer cell Ig-like receptor in human NK cells.
Purdy AK, Alvarez Arias DA, Oshinsky J, James AM, Serebriiskii I, Campbell KS
Journal of immunology (Baltimore, Md. : 1950) 2014 Nov 1;193(9):4675-83
Journal of immunology (Baltimore, Md. : 1950) 2014 Nov 1;193(9):4675-83
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 11401-1-AP(AP2A1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-AP2A1 (IP:11401-1-AP, 3ug; Detection:11401-1-AP 1:1000) with mouse skeletal muscle tissue lysate 3500ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The alpha Adaptin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human alpha Adaptin. This antibody recognizes human,mouse,rat antigen. The alpha Adaptin antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.