Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- ABIN499740 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) antibody
- Antibody type
- Polyclonal
- Antigen
- Human DFF40 (Intermediate Domain) Peptide (ABIN499739)
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.
Submitted references Operando XAFS study of catalytic NO reduction over Cu/CeO2: the effect of copper-ceria interaction under periodic operation.
The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis.
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis.
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD.
CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45.
Nagai Y, Dohmae K, Nishimura YF, Kato H, Hirata H, Takahashi N
Physical chemistry chemical physics : PCCP 2013 Jun 14;15(22):8461-5
Physical chemistry chemical physics : PCCP 2013 Jun 14;15(22):8461-5
The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis.
Liu X, Li P, Widlak P, Zou H, Luo X, Garrard WT, Wang X
Proceedings of the National Academy of Sciences of the United States of America 1998 Jul 21;95(15):8461-6
Proceedings of the National Academy of Sciences of the United States of America 1998 Jul 21;95(15):8461-6
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis.
Sakahira H, Enari M, Nagata S
Nature 1998 Jan 1;391(6662):96-9
Nature 1998 Jan 1;391(6662):96-9
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD.
Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S
Nature 1998 Jan 1;391(6662):43-50
Nature 1998 Jan 1;391(6662):43-50
CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45.
Halenbeck R, MacDonald H, Roulston A, Chen TT, Conroy L, Williams LT
Current biology : CB 1998 Apr 23;8(9):537-40
Current biology : CB 1998 Apr 23;8(9):537-40
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of DFF40 in Jurkat cell lysate with AP30288PU-N DFF40 antibody at (A) 0.5, (B) 1 and (C) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of DFF40 in K562 cells with AP30288PU-N DFF40 antibody at 10 ?g/ml.