AP08618SU-N

antibody from Acris Antibodies GmbH

Targeting: CAMK2A CAMKA, CaMKIINalpha, CaMKIIα, KIAA0968

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

AP08618SU-N

Provider

Acris Antibodies GmbH

Proper citation

Acris Antibodies GmbH Cat#AP08618SU-N, RRID:AB_1975479

Product name

anti CAMK2A/B pThr305

Antibody type

Polyclonal

Antigen

Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr305 found in rat brain CaM Kinase II.

Reactivity

Human, Mouse, Bovine, Canine, Chicken/Avian, Xenopus, Zebrafish

Host

Rabbit

Isotype

IgG

Vial size

0.1 ml

References

Submitted references

CaMKII autonomy is substrate-dependent and further stimulated by Ca2+/calmodulin.

Coultrap SJ, Buard I, Kulbe JR, Dell'Acqua ML, Bayer KU
The Journal of biological chemistry 2010 Jun 4;285(23):17930-7

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Role of Ca2+/calmodulin-dependent protein kinase II in Drosophila photoreceptors.

Lu H, Leung HT, Wang N, Pak WL, Shieh BH
The Journal of biological chemistry 2009 Apr 24;284(17):11100-9

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Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway.

Townsend M, Mehta T, Selkoe DJ
The Journal of biological chemistry 2007 Nov 16;282(46):33305-12

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Dual mechanism of a natural CaMKII inhibitor.

Vest RS, Davies KD, O'Leary H, Port JD, Bayer KU
Molecular biology of the cell 2007 Dec;18(12):5024-33

Western blot

Supportive validation

Submitted by

Acris Antibodies GmbH (provider)

Main image

Experimental details

Figure 1. Western blot of rat brain lysate showing specific immunolabeling of the ~50k Alpha- and the ~60k Beta-CaM Kinase II phosphorylated at Thr305 (Control). The immunolabeling is blocked by the phosphopeptide used as the antigen (Peptide) but not by the corresponding dephosphopeptide (not shown).