Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx011635 - Provider product page
- Provider
- Abbexa
- Product name
- E3 Ubiquitin-Protein Ligase CBL (C-CBL) Antibody
- Antibody type
- Monoclonal
- Description
- The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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