Antibody data

Product number
BS60358 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CD8B polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human CD8B.
Description
The T cell receptor (TCR) is a heterodimercomposed of either Ï« and ÉÇ or ÎÛ and Ñ´ chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficientsignal transduction through the TCR. The TCR is expressed on T helper and T cytotoxiccellsthatcan be distinguished bytheir expression of CD4 and CD8. T helpercells express CD4 proteins and T cytotoxiccells display CD8. CD8 (also designated Leu 2 or T8), a cellsurface glycoprotein, is a two chain complex(Ï«Ï« or Ï«ÉÇ) receptor that bindsclassI MHC molecules presented bythe antigen-presenting cell (APC). A primaryfunction of CD8 is to facilitate antigen recognition bythe TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cellsmay be tomaintain lowlevels of HIV expression.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CD8B protein structure - BS60358 shown in red.