Antibody data
- Antibody Data
- Antigen structure
- References [26]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 10155-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10155-1-AP, RRID:AB_2078096
- Product name
- CDC42 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CDC42 antibody (Cat. #10155-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MicroRNA-124-3p Plays a Crucial Role in Cleft Palate Induced by Retinoic Acid.
Intestinal Metabolites Influence Macrophage Phagocytosis and Clearance of Bacterial Infection.
miR-497 defect contributes to gastric cancer tumorigenesis and progression via regulating CDC42/ITGB1/FAK/PXN/AKT signaling.
Overexpression of DTL enhances cell motility and promotes tumor metastasis in cervical adenocarcinoma by inducing RAC1-JNK-FOXO1 axis.
Spatiotemporal proteomic profiling of the pro-inflammatory response to lipopolysaccharide in the THP-1 human leukaemia cell line.
EGFR and ERK activation resists flavonoid quercetin-induced anticancer activities in human cervical cancer cells in vitro.
PCGF3 promotes the proliferation and migration of non-small cell lung cancer cells via the PI3K/AKT signaling pathway.
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
DOCK7 protects against replication stress by promoting RPA stability on chromatin.
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol (SQ) inhibits cancer cell metastasis behavior of TNBC via suppressing EMT and VEGF.
FGD1 exhibits oncogenic properties in hepatocellular carcinoma through regulating cell morphology, autophagy and mitochondrial function.
Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate.
Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer.
miR-29a inhibits adhesion, migration, and invasion of osteosarcoma cells by suppressing CDC42.
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Proteomics Analysis Identifies IRSp53 and Fascin as Critical for PRV Egress and Direct Cell-Cell Transmission.
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
miR-182 suppresses invadopodia formation and metastasis in non-small cell lung cancer by targeting cortactin gene.
GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.
Inhibition of KLF5-Myo9b-RhoA Pathway-Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm.
Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module.
Dihydroartemisinin suppresses pancreatic cancer cells via a microRNA-mRNA regulatory network.
Baculovirus induces host cell aggregation via a Rho/Rok-dependent mechanism.
Energy metabolism analysis reveals the mechanism of inhibition of breast cancer cell metastasis by PEG-modified graphene oxide nanosheets.
α1β1 integrin/Rac1-dependent mesangial invasion of glomerular capillaries in Alport syndrome.
Toosendanin induces apoptosis through suppression of JNK signaling pathway in HL-60 cells.
Yoshioka H, Mikami Y, Ramakrishnan SS, Suzuki A, Iwata J
Frontiers in cell and developmental biology 2021;9:621045
Frontiers in cell and developmental biology 2021;9:621045
Intestinal Metabolites Influence Macrophage Phagocytosis and Clearance of Bacterial Infection.
O'Callaghan AA, Dempsey E, Iyer N, Stiegeler S, Mercurio K, Corr SC
Frontiers in cellular and infection microbiology 2021;11:622491
Frontiers in cellular and infection microbiology 2021;11:622491
miR-497 defect contributes to gastric cancer tumorigenesis and progression via regulating CDC42/ITGB1/FAK/PXN/AKT signaling.
Zhang L, Yao L, Zhou W, Tian J, Ruan B, Lu Z, Deng Y, Li Q, Zeng Z, Yang D, Shang R, Xu M, Zhang M, Cheng D, Yang Y, Ding Q, Yu H
Molecular therapy. Nucleic acids 2021 Sep 3;25:567-577
Molecular therapy. Nucleic acids 2021 Sep 3;25:567-577
Overexpression of DTL enhances cell motility and promotes tumor metastasis in cervical adenocarcinoma by inducing RAC1-JNK-FOXO1 axis.
Liu S, Gu L, Wu N, Song J, Yan J, Yang S, Feng Y, Wang Z, Wang L, Zhang Y, Jin Y
Cell death & disease 2021 Oct 11;12(10):929
Cell death & disease 2021 Oct 11;12(10):929
Spatiotemporal proteomic profiling of the pro-inflammatory response to lipopolysaccharide in the THP-1 human leukaemia cell line.
Mulvey CM, Breckels LM, Crook OM, Sanders DJ, Ribeiro ALR, Geladaki A, Christoforou A, Britovšek NK, Hurrell T, Deery MJ, Gatto L, Smith AM, Lilley KS
Nature communications 2021 Oct 1;12(1):5773
Nature communications 2021 Oct 1;12(1):5773
EGFR and ERK activation resists flavonoid quercetin-induced anticancer activities in human cervical cancer cells in vitro.
Chen X, Xu P, Zhang H, Su X, Guo L, Zhou X, Wang J, Huang P, Zhang Q, Sun R
Oncology letters 2021 Nov;22(5):754
Oncology letters 2021 Nov;22(5):754
PCGF3 promotes the proliferation and migration of non-small cell lung cancer cells via the PI3K/AKT signaling pathway.
Hu Y, Cheng Y, Jiang X, Zhang Y, Wang H, Ren H, Xu Y, Jiang J, Wang Q, Su H, Zhang B, Qiu X
Experimental cell research 2021 Mar 15;400(2):112496
Experimental cell research 2021 Mar 15;400(2):112496
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Wang P, Wang C, Liu C
Oncology letters 2021 Jan;21(1):59
Oncology letters 2021 Jan;21(1):59
DOCK7 protects against replication stress by promoting RPA stability on chromatin.
Gao M, Guo G, Huang J, Hou X, Ham H, Kim W, Zhao F, Tu X, Zhou Q, Zhang C, Zhu Q, Liu J, Yan Y, Xu Z, Yin P, Luo K, Weroha J, Deng M, Billadeau DD, Lou Z
Nucleic acids research 2021 Apr 6;49(6):3322-3337
Nucleic acids research 2021 Apr 6;49(6):3322-3337
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol (SQ) inhibits cancer cell metastasis behavior of TNBC via suppressing EMT and VEGF.
Zheng D, Wu Z, Han J, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Chemico-biological interactions 2020 Sep 25;329:109202
Chemico-biological interactions 2020 Sep 25;329:109202
FGD1 exhibits oncogenic properties in hepatocellular carcinoma through regulating cell morphology, autophagy and mitochondrial function.
Zeng Y, Guo Z, Hu Z, Liu M, Chen Y, Chen S, Peng B, Zhang P, Wu Z, Luo H, Zhong F, Jiang K, Lu Y, Yuan G, He S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110029
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110029
Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate.
Li M, Min W, Wang J, Wang L, Li Y, Zhou N, Yang Z, Qian Q
Experimental and therapeutic medicine 2020 Apr;19(4):2861-2870
Experimental and therapeutic medicine 2020 Apr;19(4):2861-2870
Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer.
Zhao Z, Li L, Du P, Ma L, Zhang W, Zheng L, Lan B, Zhang B, Ma F, Xu B, Zhan Q, Song Y
Theranostics 2019;9(5):1401-1416
Theranostics 2019;9(5):1401-1416
miR-29a inhibits adhesion, migration, and invasion of osteosarcoma cells by suppressing CDC42.
Liu ZJ, Chen SG, Yang YZ, Lu SJ, Zhao XM, Hu B, Zhang L
International journal of clinical and experimental pathology 2019;12(11):4171-4180
International journal of clinical and experimental pathology 2019;12(11):4171-4180
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Wang X, Adegoke EO, Ma M, Huang F, Zhang H, Adeniran SO, Zheng P, Zhang G
Theriogenology 2019 Oct 15;138:84-93
Theriogenology 2019 Oct 15;138:84-93
Proteomics Analysis Identifies IRSp53 and Fascin as Critical for PRV Egress and Direct Cell-Cell Transmission.
Yu FL, Miao H, Xia J, Jia F, Wang H, Xu F, Guo L
Proteomics 2019 Dec;19(23):e1900009
Proteomics 2019 Dec;19(23):e1900009
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion.
Li M, Wen Y, Zhang R, Xie F, Zhang G, Qin X
Brain research bulletin 2018 Sep;142:54-62
Brain research bulletin 2018 Sep;142:54-62
miR-182 suppresses invadopodia formation and metastasis in non-small cell lung cancer by targeting cortactin gene.
Li Y, Zhang H, Gong H, Yuan Y, Li Y, Wang C, Li W, Zhang Z, Liu M, Liu H, Chen J
Journal of experimental & clinical cancer research : CR 2018 Jul 9;37(1):141
Journal of experimental & clinical cancer research : CR 2018 Jul 9;37(1):141
GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.
Pan X, Zhang R, Xie C, Gan M, Yao S, Yao Y, Jin J, Han T, Huang Y, Gong Y, Wang J, Yu B
American journal of translational research 2017;9(9):4217-4226
American journal of translational research 2017;9(9):4217-4226
Inhibition of KLF5-Myo9b-RhoA Pathway-Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm.
Ma D, Zheng B, Suzuki T, Zhang R, Jiang C, Bai D, Yin W, Yang Z, Zhang X, Hou L, Zhan H, Wen JK
Circulation research 2017 Mar 3;120(5):799-815
Circulation research 2017 Mar 3;120(5):799-815
Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module.
Liang D, Wang Z, Yan Z, Hou S, Xu W, Wang L, Shang M, Qiao Z
Scientific reports 2017 Mar 2;7:43798
Scientific reports 2017 Mar 2;7:43798
Dihydroartemisinin suppresses pancreatic cancer cells via a microRNA-mRNA regulatory network.
Li Y, Wang Y, Kong R, Xue D, Pan S, Chen H, Sun B
Oncotarget 2016 Sep 20;7(38):62460-62473
Oncotarget 2016 Sep 20;7(38):62460-62473
Baculovirus induces host cell aggregation via a Rho/Rok-dependent mechanism.
Deng Z, Huang Z, Yuan M, Yang K, Pang Y
The Journal of general virology 2014 Oct;95(Pt 10):2310-2320
The Journal of general virology 2014 Oct;95(Pt 10):2310-2320
Energy metabolism analysis reveals the mechanism of inhibition of breast cancer cell metastasis by PEG-modified graphene oxide nanosheets.
Zhou T, Zhang B, Wei P, Du Y, Zhou H, Yu M, Yan L, Zhang W, Nie G, Chen C, Tu Y, Wei T
Biomaterials 2014 Dec;35(37):9833-9843
Biomaterials 2014 Dec;35(37):9833-9843
α1β1 integrin/Rac1-dependent mesangial invasion of glomerular capillaries in Alport syndrome.
Zallocchi M, Johnson BM, Meehan DT, Delimont D, Cosgrove D
The American journal of pathology 2013 Oct;183(4):1269-1280
The American journal of pathology 2013 Oct;183(4):1269-1280
Toosendanin induces apoptosis through suppression of JNK signaling pathway in HL-60 cells.
Ju J, Qi Z, Cai X, Cao P, Liu N, Wang S, Chen Y
Toxicology in vitro : an international journal published in association with BIBRA 2013 Feb;27(1):232-8
Toxicology in vitro : an international journal published in association with BIBRA 2013 Feb;27(1):232-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 10155-1-AP(CDC42 antibody) at dilution of 1:0
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CDC42 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CDC42. This antibody recognizes human, mouse, rat antigen. The CDC42 antibody has been validated for the following applications: ELISA, WB, IHC analysis.