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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Western blot [1]
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- Product number
- PA1366 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-CDC42 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for CDC42 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Bovine. CDC42 information: Molecular Weight: 21259 MW; Subcellular Localization: Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Midbody. Localizes to spindle during prometaphase cells. Moves to the central spindle as cells progressed through anaphase to telophase. Localizes at the end of cytokinesis in the intercellular bridge formed between two daughter cells. Its localization is regulated by the activities of guanine nucleotide exchange factor ECT2 and GTPase activating protein RACGAP1. Colocalizes with NEK6 in the centrosome.
- Reactivity
- Human, Mouse, Rat, Bovine
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references The miR-29 family members induce glioblastoma cell apoptosis by targeting cell division cycle 42 in a p53-dependent manner.
Syndecan-4 assists Mycobacterium tuberculosis entry into lung epithelial cells by regulating the Cdc42, N-WASP, and Arp2/3 signaling pathways.
Cytotoxic necrotizing factor 1 promotes bladder cancer angiogenesis through activating RhoC.
Chronic asthma-induced behavioral and hippocampal neuronal morphological changes are concurrent with BDNF, cofilin1 and Cdc42/RhoA alterations in immature mice.
Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in Alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and RAC1/CDC42 alterations in rats.
Shi C, Luo W, Sun C, Yu L, Zhou X, Hua D, Jiang Z, Wang Q, Yu S
European journal of clinical investigation 2023 Jun;53(6):e13964
European journal of clinical investigation 2023 Jun;53(6):e13964
Syndecan-4 assists Mycobacterium tuberculosis entry into lung epithelial cells by regulating the Cdc42, N-WASP, and Arp2/3 signaling pathways.
Wen D, Cui J, Li P, Xiong Q, Chen G, Wu C
Microbes and infection 2022 Jun;24(4):104931
Microbes and infection 2022 Jun;24(4):104931
Cytotoxic necrotizing factor 1 promotes bladder cancer angiogenesis through activating RhoC.
Guo Y, Wang J, Zhou K, Lv J, Wang L, Gao S, Keller ET, Zhang ZS, Wang Q, Yao Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):7927-7940
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):7927-7940
Chronic asthma-induced behavioral and hippocampal neuronal morphological changes are concurrent with BDNF, cofilin1 and Cdc42/RhoA alterations in immature mice.
Zhuang TT, Pan C, Chen JJ, Han F, Zhu XL, Xu H, Lu YP
Brain research bulletin 2018 Oct;143:194-206
Brain research bulletin 2018 Oct;143:194-206
Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in Alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and RAC1/CDC42 alterations in rats.
Han F, Zhuang TT, Chen JJ, Zhu XL, Cai YF, Lu YP
PloS one 2017;12(9):e0185102
PloS one 2017;12(9):e0185102
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-CDC42 antibody, PA1366, Western blottingLane 1: Recombinant Human CDC42 Protein 10ngLane 2: Recombinant Human CDC42 Protein 5ngLane 3: Recombinant Human CDC42 Protein 2.5ng
- Additional image
