CABT-B1850
antibody from Creative Diagnostics
Targeting: DIDO1
BYE1, C20orf158, DATF1, DIO-1, DIO1, dJ885L7.8, FLJ11265, KIAA0333
Antibody data
- Antibody Data
- Antigen structure
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- Comments [0]
- Validations [0]
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- Product number
- CABT-B1850 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-Dido3 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Death inducer obliterator 3 (Dido3) is a transcription factor encoded by the DIDO1 (also known as BYE1, DIO1, DATF1, DIDO2, DIDO3) gene in human. Three other isoforms, including Dido1 & 2 (isoform 2 & 1, respectively), are also encoded by the same gene through alternative splicing. In addition to early research activities regarding apoptosis-inducing activity of Dido proteins, later studies reveal important roles of Dido1 & Dido3 (isoform 4) in maintaining stem cell genomic stability and self-renewal. Dido3 binds histone H3K4me3 in the nucleus. Histone H3T3 or H3T6 phosphorylation causes H3K4 demethylation and Dido3 translocation from chromatin to the mitotic spindle.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 _g
- Concentration
- Please refer to lot specific datasheet.
- Storage
- Stable for 1 year at 2-8°C from date of receipt.
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