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- Antibody Data
- Antigen structure
- References [9]
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- Western blot [1]
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- Product number
- 15646-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15646-1-AP, RRID:AB_2252572
- Product name
- POLD1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated POLD1 antibody (Cat. #15646-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hepatitis B virus cccDNA is formed through distinct repair processes of each strand.
Core components of DNA lagging strand synthesis machinery are essential for hepatitis B virus cccDNA formation.
Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis.
ISCA1 mutation in a patient with infantile-onset leukodystrophy causes defects in mitochondrial [4Fe-4S] proteins.
Elevated expression of POLD1 is associated with poor prognosis in breast cancer.
Cytosolic HSC20 integrates de novo iron-sulfur cluster biogenesis with the CIAO1-mediated transfer to recipients.
Cellular requirements for iron-sulfur cluster insertion into the antiviral radical SAM protein viperin.
p53 inhibits the expression of p125 and the methylation of POLD1 gene promoter by downregulating the Sp1-induced DNMT1 activities in breast cancer.
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.
Wei L, Ploss A
Nature communications 2021 Mar 11;12(1):1591
Nature communications 2021 Mar 11;12(1):1591
Core components of DNA lagging strand synthesis machinery are essential for hepatitis B virus cccDNA formation.
Wei L, Ploss A
Nature microbiology 2020 May;5(5):715-726
Nature microbiology 2020 May;5(5):715-726
Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis.
Maio N, Kim KS, Holmes-Hampton G, Singh A, Rouault TA
Haematologica 2019 Sep;104(9):1756-1767
Haematologica 2019 Sep;104(9):1756-1767
ISCA1 mutation in a patient with infantile-onset leukodystrophy causes defects in mitochondrial [4Fe-4S] proteins.
Torraco A, Stehling O, Stümpfig C, Rösser R, De Rasmo D, Fiermonte G, Verrigni D, Rizza T, Vozza A, Di Nottia M, Diodato D, Martinelli D, Piemonte F, Dionisi-Vici C, Bertini E, Lill R, Carrozzo R
Human molecular genetics 2018 Oct 15;27(20):3650
Human molecular genetics 2018 Oct 15;27(20):3650
Elevated expression of POLD1 is associated with poor prognosis in breast cancer.
Qin Q, Tan Q, Li J, Yang W, Lian B, Mo Q, Wei C
Oncology letters 2018 Nov;16(5):5591-5598
Oncology letters 2018 Nov;16(5):5591-5598
Cytosolic HSC20 integrates de novo iron-sulfur cluster biogenesis with the CIAO1-mediated transfer to recipients.
Kim KS, Maio N, Singh A, Rouault TA
Human molecular genetics 2018 Mar 1;27(5):837-852
Human molecular genetics 2018 Mar 1;27(5):837-852
Cellular requirements for iron-sulfur cluster insertion into the antiviral radical SAM protein viperin.
Upadhyay AS, Stehling O, Panayiotou C, Rösser R, Lill R, Överby AK
The Journal of biological chemistry 2017 Aug 18;292(33):13879-13889
The Journal of biological chemistry 2017 Aug 18;292(33):13879-13889
p53 inhibits the expression of p125 and the methylation of POLD1 gene promoter by downregulating the Sp1-induced DNMT1 activities in breast cancer.
Zhang L, Yang W, Zhu X, Wei C
OncoTargets and therapy 2016;9:1351-60
OncoTargets and therapy 2016;9:1351-60
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.
Stehling O, Vashisht AA, Mascarenhas J, Jonsson ZO, Sharma T, Netz DJ, Pierik AJ, Wohlschlegel JA, Lill R
Science (New York, N.Y.) 2012 Jul 13;337(6091):195-9
Science (New York, N.Y.) 2012 Jul 13;337(6091):195-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The POLD1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human POLD1. This antibody recognizes human, mouse, rat antigen. The POLD1 antibody has been validated for the following applications: ELISA, WB analysis.
