Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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Comment
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- Product number
- ABIN1450105 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- 15 amino acid synthetic peptide near the amino terminus of human RAPGEF4 / EPAC2
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function.
Cell physiology of cAMP sensor Epac.
Characterization of the gene EPAC2: structure, chromosomal localization, tissue expression, and identification of the liver-specific isoform.
Grandoch M, Roscioni SS, Schmidt M
British journal of pharmacology 2010 Jan 1;159(2):265-84
British journal of pharmacology 2010 Jan 1;159(2):265-84
Cell physiology of cAMP sensor Epac.
Holz GG, Kang G, Harbeck M, Roe MW, Chepurny OG
The Journal of physiology 2006 Nov 15;577(Pt 1):5-15
The Journal of physiology 2006 Nov 15;577(Pt 1):5-15
Characterization of the gene EPAC2: structure, chromosomal localization, tissue expression, and identification of the liver-specific isoform.
Ueno H, Shibasaki T, Iwanaga T, Takahashi K, Yokoyama Y, Liu LM, Yokoi N, Ozaki N, Matsukura S, Yano H, Seino S
Genomics 2001 Nov;78(1-2):91-8
Genomics 2001 Nov;78(1-2):91-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of EPAC2 in rat liver tissue lysate with EPAC2 antibody Cat.-No. AP55604PU-N at 1 ?g/ml in (A) the absence and (B) the presence of blocking peptide.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of EPAC3 in mouse liver tissue with EPAC3 antibody Cat.-No. AP55604PU-N at 2.5 μg/ml.