BS3275

antibody from Bioworld Technology, Inc
Targeting: CLIP1 CLIP, CLIP-170, CLIP170, CYLN1, RSN
Provider product page for BS3275

Antibody data

Product number
BS3275 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3275, RRID:AB_1662148
Product name
CLIP 170 (K1332) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 1300-1350 of Human CLIP-170.
Description
Cytoplasmic linker protein of 170 kDa (CLIP-170) is the original member of a group of microtuble binding proteins designated as plus-end-binding proteins(+TIPs). CLIP-170 binds to the growing plus ends of microtubules and acts as a linker between the dynamic microtubule ends and organelle membranes. The protein acts as an anticatastrophic factor, promoting microtubule rescue near the cell periphery. Fluorescently labeled CLIP-170 can be visualized as a comet like streak around the growing ends of microtubules. CLIP-170 colocalizes with dynactin and dynein at microtubule ends and also at the kinetochore. Restin, first identified as a marker for Hodgkin and Reed-Sternberg (HRS) cells, is a 160 kDa splice variant of the gene that includes a 35 amino acid stretch not present in CLIP-170.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CLIP1 protein structure - BS3275 shown in red.