ABIN361885

antibody from antibodies-online

Targeting: GSK3A

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN361885

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN361885, RRID:AB_10953100

Product name

anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (pSer21) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pSer21 (T-S-S (p) -F-A) derived from Human GSK3a. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer21

Isotype

IgG

Vial size

50 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway.

Liu D, Huang Y, Zeng J, Chen B, Huang N, Guo N, Liu L, Xu H, Mo X, Li W
Journal of cancer research and clinical oncology 2011 Nov;137(11):1629-40

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Glycogen synthase kinase-3 regulates formation of long lamellipodia in human keratinocytes.

Koivisto L, Alavian K, Hakkinen L, Pelech S, McCulloch CA, Larjava H
Journal of cell science 2003 Sep 15;116(Pt 18):3749-60

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Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin.

Srivastava AK, Pandey SK
Molecular and cellular biochemistry 1998 May;182(1-2):135-41

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GSK3: a SHAGGY frog story.

Welsh GI, Wilson C, Proud CG
Trends in cell biology 1996 Jul;6(7):274-9