M00971

antibody from Boster Biological Technology

Targeting: HDAC4 BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

M00971

Provider

Boster Biological Technology

Product name

Anti-HDAC4/Histone Deacetylase 4 Rabbit Monoclonal Antibody

Antibody type

Monoclonal

Description

Monoclonal antibody for Histone Deacetylase 4/HDAC4 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IF, ICC, WB. Reactive species: Human Histone Deacetylase 4/HDAC4 information: Molecular Weight: 119040 MW; Subcellular Localization: Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. Upon muscle cells differentiation, it accumulates in the nuclei of myotubes, suggesting a positive role of nuclear HDAC4 in muscle differentiation. The export to cytoplasm depends on the interaction with a 14-3-3 chaperone protein and is due to its phosphorylation at Ser-246, Ser-467 and Ser-632 by CaMK4 and SIK1. The nuclear localization probably depends on sumoylation; Tissue Specificity: Ubiquitous.

Reactivity

Human

Host

Rabbit

Antibody clone number

HGI-8

Vial size

100ug/vial

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage

At -20°C for one year. Avoid repeated freezing and thawing.