ABIN493047

antibody from antibodies-online

Targeting: HDAC4 BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN493047

Provider

antibodies-online

Product name

anti-Histone Deacetylase 4 (HDAC4) (AA 954-972) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide corresponding to amino acid 954-972 of human HDAC4

Description

Affinity chromatography

Reactivity

Human, Mouse, Rat, Simian

Host

Rabbit

Antigen sequence

VKPAEKRPDEEPMEEEPPL


Epitope

AA 954-972

Vial size

0.1 mg

Concentration

0.55 - 0.63 mg/mL

Storage

Store (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

HDAC4 promotes growth of colon cancer cells via repression of p21.

Wilson AJ, Byun DS, Nasser S, Murray LB, Ayyanar K, Arango D, Figueroa M, Melnick A, Kao GD, Augenlicht LH, Mariadason JM
Molecular biology of the cell 2008 Oct;19(10):4062-75

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Anticancer activities of histone deacetylase inhibitors.

Bolden JE, Peart MJ, Johnstone RW
Nature reviews. Drug discovery 2006 Sep;5(9):769-84

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Class II histone deacetylases: from sequence to function, regulation, and clinical implication.

Yang XJ, Grégoire S
Molecular and cellular biology 2005 Apr;25(8):2873-84

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Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response.

Kao GD, McKenna WG, Guenther MG, Muschel RJ, Lazar MA, Yen TJ
The Journal of cell biology 2003 Mar 31;160(7):1017-27

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Histone deacetylase 4 possesses intrinsic nuclear import and export signals.

Wang AH, Yang XJ
Molecular and cellular biology 2001 Sep;21(17):5992-6005