Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [1]
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Validation data
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- Product number
- 12433-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12433-1-AP, RRID:AB_2295573
- Product name
- HOMER1 antibody
- Antibody type
- Polyclonal
- Description
- HOMER1 antibody (Cat. #12433-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding.
Bilirubin impairs neuritogenesis and synaptogenesis in NSPCs by downregulating NMDAR-CREB-BDNF signaling.
Ndufa4 Regulates the Proliferation and Apoptosis of Neurons via miR-145a-5p/Homer1/Ccnd2.
Overexpression of Homer1b/c induces valproic acid resistance in epilepsy.
Engineered fast-dissociating antibody fragments for multiplexed super-resolution microscopy.
A recurrent SHANK1 mutation implicated in autism spectrum disorder causes autistic-like core behaviors in mice via downregulation of mGluR1-IP3R1-calcium signaling.
sTREM-1 promotes the phagocytic function of microglia to induce hippocampus damage via the PI3K-AKT signaling pathway.
Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X.
Liraglutide preconditioning attenuates myocardial ischemia/ reperfusion injury via homer1 activation.
Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations.
Distinct and Overlapping Expression Patterns of the Homer Family of Scaffolding Proteins and Their Encoding Genes in Developing Murine Cephalic Tissues.
A Putative Mechanism of Age-Related Synaptic Dysfunction Based on the Impact of IGF-1 Receptor Signaling on Synaptic CaMKIIα Phosphorylation.
Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid.
Acid-sensing ion channels activation and hypoxia upregulate Homer1a expression.
Lithium attenuates scopolamine-induced memory deficits with inhibition of GSK-3β and preservation of postsynaptic components.
Tissue kallikrein protects neurons from hypoxia/reoxygenation-induced cell injury through Homer1b/c.
Hacisuleyman E, Hale CR, Noble N, Luo JD, Fak JJ, Saito M, Chen J, Weissman JS, Darnell RB
Nature neuroscience 2024 May;27(5):822-835
Nature neuroscience 2024 May;27(5):822-835
Bilirubin impairs neuritogenesis and synaptogenesis in NSPCs by downregulating NMDAR-CREB-BDNF signaling.
Zhang Y, Li S, Li L, Huang H, Fu Z, Hua Z
In vitro cellular & developmental biology. Animal 2024 Mar;60(2):161-171
In vitro cellular & developmental biology. Animal 2024 Mar;60(2):161-171
Ndufa4 Regulates the Proliferation and Apoptosis of Neurons via miR-145a-5p/Homer1/Ccnd2.
Fu F, Chen C, Du K, Li LS, Li R, Lei TY, Deng Q, Wang D, Yu QX, Yang X, Han J, Pan M, Zhen L, Zhang LN, Li J, Li FT, Zhang YL, Jing XY, Li FC, Li DZ, Liao C
Molecular neurobiology 2023 Jun;60(6):2986-3003
Molecular neurobiology 2023 Jun;60(6):2986-3003
Overexpression of Homer1b/c induces valproic acid resistance in epilepsy.
Wang Y, Li Y, Wang G, Lu J, Li Z
CNS neuroscience & therapeutics 2023 Jan;29(1):331-343
CNS neuroscience & therapeutics 2023 Jan;29(1):331-343
Engineered fast-dissociating antibody fragments for multiplexed super-resolution microscopy.
Zhang Q, Miyamoto A, Watanabe S, Arimori T, Sakai M, Tomisaki M, Kiuchi T, Takagi J, Watanabe N
Cell reports methods 2022 Oct 24;2(10):100301
Cell reports methods 2022 Oct 24;2(10):100301
A recurrent SHANK1 mutation implicated in autism spectrum disorder causes autistic-like core behaviors in mice via downregulation of mGluR1-IP3R1-calcium signaling.
Qin Y, Du Y, Chen L, Liu Y, Xu W, Liu Y, Li Y, Leng J, Wang Y, Zhang XY, Feng J, Zhang F, Jin L, Qiu Z, Gong X, Wang H
Molecular psychiatry 2022 Jul;27(7):2985-2998
Molecular psychiatry 2022 Jul;27(7):2985-2998
sTREM-1 promotes the phagocytic function of microglia to induce hippocampus damage via the PI3K-AKT signaling pathway.
Lu L, Liu X, Fu J, Liang J, Hou Y, Dou H
Scientific reports 2022 Apr 29;12(1):7047
Scientific reports 2022 Apr 29;12(1):7047
Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X.
So LY, Miller JE
Behavioural brain research 2021 Feb 1;398:112955
Behavioural brain research 2021 Feb 1;398:112955
Liraglutide preconditioning attenuates myocardial ischemia/ reperfusion injury via homer1 activation.
Cui X, Liang H, Hao C, Jing X
Aging 2021 Feb 1;13(5):6625-6633
Aging 2021 Feb 1;13(5):6625-6633
Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations.
Chen C, Soto G, Dumrongprechachan V, Bannon N, Kang S, Kozorovitskiy Y, Parisiadou L
eLife 2020 Oct 2;9
eLife 2020 Oct 2;9
Distinct and Overlapping Expression Patterns of the Homer Family of Scaffolding Proteins and Their Encoding Genes in Developing Murine Cephalic Tissues.
Reibring CG, Hallberg K, Linde A, Gritli-Linde A
International journal of molecular sciences 2020 Feb 13;21(4)
International journal of molecular sciences 2020 Feb 13;21(4)
A Putative Mechanism of Age-Related Synaptic Dysfunction Based on the Impact of IGF-1 Receptor Signaling on Synaptic CaMKIIα Phosphorylation.
Ogundele OM, Pardo J, Francis J, Goya RG, Lee CC
Frontiers in neuroanatomy 2018;12:35
Frontiers in neuroanatomy 2018;12:35
Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid.
El Shahawy M, Reibring CG, Neben CL, Hallberg K, Marangoni P, Harfe BD, Klein OD, Linde A, Gritli-Linde A
PLoS genetics 2017 Jul;13(7):e1006914
PLoS genetics 2017 Jul;13(7):e1006914
Acid-sensing ion channels activation and hypoxia upregulate Homer1a expression.
Su JJ, Pan H, Zhou HG, Tang YP, Dong Q, Liu JR
CNS neuroscience & therapeutics 2014 Mar;20(3):264-74
CNS neuroscience & therapeutics 2014 Mar;20(3):264-74
Lithium attenuates scopolamine-induced memory deficits with inhibition of GSK-3β and preservation of postsynaptic components.
Wu YY, Wang X, Tan L, Liu D, Liu XH, Wang Q, Wang JZ, Zhu LQ
Journal of Alzheimer's disease : JAD 2013;37(3):515-27
Journal of Alzheimer's disease : JAD 2013;37(3):515-27
Tissue kallikrein protects neurons from hypoxia/reoxygenation-induced cell injury through Homer1b/c.
Su J, Tang Y, Zhou H, Liu L, Dong Q
Cellular signalling 2012 Nov;24(11):2205-15
Cellular signalling 2012 Nov;24(11):2205-15
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 12433-1-AP(HOMER1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HOMER1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HOMER1. This antibody recognizes human,mouse,rat antigen. The HOMER1 antibody has been validated for the following applications: ELISA, IHC, WB, FC analysis.