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Learn10875-1-AP
antibody from Proteintech Group
Targeting: SERPINH1
CBP1, CBP2, colligen, HSP47, SERPINH2
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10875-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10875-1-AP, RRID:AB_2301500
- Product name
- HSP47 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HSP47 antibody (Cat. #10875-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Thioredoxin-1 Inhibits Golgi Stress Induced by Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine.
Chiral Polyproline Enables Functional Stealth for Simultaneous Long Circulation and Endoplasmic Reticulum-Targeted Antigen Presentation.
SERPINH1 functions as a multifunctional regulator to promote the malignant progression of cervical cancer.
Activin B Regulates Fibroblasts to Promote Granulation Tissue Formation and Angiogenesis During Murine Skin-Wound Healing via the JNK/ERK Signaling Pathway.
SERPINH1 promotes malignant progression of laryngeal squamous cell carcinoma via COL7A1-mediated Wnt/β-catenin signaling.
The JAK1/STAT3 pathway mediates the effects of SERPINH1 on glioma EMT.
Ether bond-modified lipid nanoparticles for enhancing the treatment effect of hepatic fibrosis.
Machine learning-based construction of Immunogenic cell death-related score for improving prognosis and personalized treatment in glioma.
Pathological characterization of female reproductive organs prior to miscarriage induced by Zika virus infection in the pregnant common marmoset.
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
HSP47 Increases the Expression of Type I Collagen in Fibroblasts through IRE1α Activation, XBP1 Splicing, and Nuclear Translocation of β-Catenin.
FOXL1+ Telocytes in mouse colon orchestrate extracellular matrix biodynamics and wound repair resolution.
SCNN1B regulates the proliferation, migration, and collagen deposition of human lung fibroblasts.
A Shape-Adaptive Gallic Acid Driven Multifunctional Adhesive Hydrogel Loaded with Scolopin2 for Wound Repair.
Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomes.
Responsive and activable nanomedicines for remodeling the tumor microenvironment.
Proteomic Profiling Identifies Kaposi's Sarcoma-Associated Herpesvirus (KSHV)-Encoded LANA(SIM)-Associated Proteins in Hypoxia.
RUNX1 Is a Driver of Renal Cell Carcinoma Correlating with Clinical Outcome.
Development of a Gene Delivery System of Oligonucleotides for Fibroses by Targeting Cell-Surface Vimentin-Expressing Cells with N-Acetylglucosamine-Bearing Polymer-Conjugated Polyethyleneimine.
Cyclophilin B control of lysine post-translational modifications of skin type I collagen.
Loss of function of Colgalt1 disrupts collagen post-translational modification and causes musculoskeletal defects.
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
Duan J, Sun X, Wei Y, Pan Y, Bai L, Yan F, Bai J
Antioxidants & redox signaling 2026 May;44(13-15):661-675
Antioxidants & redox signaling 2026 May;44(13-15):661-675
Chiral Polyproline Enables Functional Stealth for Simultaneous Long Circulation and Endoplasmic Reticulum-Targeted Antigen Presentation.
Hu M, He Y, Wu L, Su W, Zhang W, Yu X, Guo M, Li Y, Lu H, Chen C, Cai R
ACS nano 2026 Mar 10;20(9):7908-7927
ACS nano 2026 Mar 10;20(9):7908-7927
SERPINH1 functions as a multifunctional regulator to promote the malignant progression of cervical cancer.
Liu Q, Peng Y, Liu W, Luo X
PloS one 2025;20(7):e0329007
PloS one 2025;20(7):e0329007
Activin B Regulates Fibroblasts to Promote Granulation Tissue Formation and Angiogenesis During Murine Skin-Wound Healing via the JNK/ERK Signaling Pathway.
Xu J, Wang X, Zhao S, Chen X, Wu W, Zhang Y, Chen Q, Xu X, Yang X, Zhang M, Zhang L
International journal of molecular sciences 2025 Oct 22;26(21)
International journal of molecular sciences 2025 Oct 22;26(21)
SERPINH1 promotes malignant progression of laryngeal squamous cell carcinoma via COL7A1-mediated Wnt/β-catenin signaling.
He F, Li J, Tong W, Wang S, Wang H, Huang B, Teng B
Cellular signalling 2025 Nov;135:112043
Cellular signalling 2025 Nov;135:112043
The JAK1/STAT3 pathway mediates the effects of SERPINH1 on glioma EMT.
Wang S, Sun Z, Wang C, Zhang A, Zhang C, Hou S, Lin N, Li Q
International immunopharmacology 2025 Jun 5;157:114731
International immunopharmacology 2025 Jun 5;157:114731
Ether bond-modified lipid nanoparticles for enhancing the treatment effect of hepatic fibrosis.
Chu R, Kong J, Gao Q, Yang Y, Pan T, Lu X, Wang Z, Wang Y, He J
International journal of pharmaceutics 2025 Feb 25;671:125192
International journal of pharmaceutics 2025 Feb 25;671:125192
Machine learning-based construction of Immunogenic cell death-related score for improving prognosis and personalized treatment in glioma.
Li G, Zhao Y, He Y, Qian Z, Liu Y, Li X, Li L, Liu Z
Scientific reports 2025 Aug 19;15(1):30417
Scientific reports 2025 Aug 19;15(1):30417
Pathological characterization of female reproductive organs prior to miscarriage induced by Zika virus infection in the pregnant common marmoset.
Imagawa T, Tanaka K, Ito M, Matsuda M, Suzuki T, Ando T, Yaguchi C, Miyamoto K, Takabayashi S, Suzuki R, Takasaki T, Itoh H, Kosugi I, Suzuki T
Microbiology spectrum 2025 Apr;13(4):e0228224
Microbiology spectrum 2025 Apr;13(4):e0228224
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
Wang L, Li C, Zhan H, Li S, Zeng K, Xu C, Zou Y, Xie Y, Zhan Z, Yin S, Zeng Y, Chen X, Lv G, Han Z, Zhou D, Zhou D, Yang Y, Zhou A
Cell reports. Medicine 2024 May 21;5(5):101533
Cell reports. Medicine 2024 May 21;5(5):101533
HSP47 Increases the Expression of Type I Collagen in Fibroblasts through IRE1α Activation, XBP1 Splicing, and Nuclear Translocation of β-Catenin.
Ham SY, Pyo MJ, Kang M, Kim YS, Lee DH, Chung JH, Lee ST
Cells 2024 Mar 17;13(6)
Cells 2024 Mar 17;13(6)
FOXL1+ Telocytes in mouse colon orchestrate extracellular matrix biodynamics and wound repair resolution.
Pomerleau V, Nicolas VR, Jurkovic CM, Faucheux N, Lauzon MA, Boisvert FM, Perreault N
Journal of proteomics 2023 Jan 16;271:104755
Journal of proteomics 2023 Jan 16;271:104755
SCNN1B regulates the proliferation, migration, and collagen deposition of human lung fibroblasts.
Yan Y, Zhang Y, Zhang J, Ying L
In vitro cellular & developmental biology. Animal 2023 Aug;59(7):479-485
In vitro cellular & developmental biology. Animal 2023 Aug;59(7):479-485
A Shape-Adaptive Gallic Acid Driven Multifunctional Adhesive Hydrogel Loaded with Scolopin2 for Wound Repair.
Chen H, Zheng T, Wu C, Wang J, Ye F, Cui M, Sun S, Zhang Y, Li Y, Dong Z
Pharmaceuticals (Basel, Switzerland) 2022 Nov 17;15(11)
Pharmaceuticals (Basel, Switzerland) 2022 Nov 17;15(11)
Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomes.
Terajima M, Taga Y, Nakamura T, Guo HF, Kayashima Y, Maeda-Smithies N, Parag-Sharma K, Kim JS, Amelio AL, Mizuno K, Kurie JM, Yamauchi M
Scientific reports 2022 Aug 22;12(1):14256
Scientific reports 2022 Aug 22;12(1):14256
Responsive and activable nanomedicines for remodeling the tumor microenvironment.
Zhang Y, Han X, Nie G
Nature protocols 2021 Jan;16(1):405-430
Nature protocols 2021 Jan;16(1):405-430
Proteomic Profiling Identifies Kaposi's Sarcoma-Associated Herpesvirus (KSHV)-Encoded LANA(SIM)-Associated Proteins in Hypoxia.
Liu X, Gan J, Du S, Zhu C, Wang Y, Jia Y, Zhang D, Qu D, Wei F, Robertson ES, Cai Q
mSystems 2021 Dec 21;6(6):e0110921
mSystems 2021 Dec 21;6(6):e0110921
RUNX1 Is a Driver of Renal Cell Carcinoma Correlating with Clinical Outcome.
Rooney N, Mason SM, McDonald L, Däbritz JHM, Campbell KJ, Hedley A, Howard S, Athineos D, Nixon C, Clark W, Leach JDG, Sansom OJ, Edwards J, Cameron ER, Blyth K
Cancer research 2020 Jun 1;80(11):2325-2339
Cancer research 2020 Jun 1;80(11):2325-2339
Development of a Gene Delivery System of Oligonucleotides for Fibroses by Targeting Cell-Surface Vimentin-Expressing Cells with N-Acetylglucosamine-Bearing Polymer-Conjugated Polyethyleneimine.
Song I, Ise H
Polymers 2020 Jul 7;12(7)
Polymers 2020 Jul 7;12(7)
Cyclophilin B control of lysine post-translational modifications of skin type I collagen.
Terajima M, Taga Y, Cabral WA, Liu Y, Nagasawa M, Sumida N, Kayashima Y, Chandrasekaran P, Han L, Maeda N, Perdivara I, Hattori S, Marini JC, Yamauchi M
PLoS genetics 2019 Jun;15(6):e1008196
PLoS genetics 2019 Jun;15(6):e1008196
Loss of function of Colgalt1 disrupts collagen post-translational modification and causes musculoskeletal defects.
Geister KA, Lopez-Jimenez AJ, Houghtaling S, Ho TH, Vanacore R, Beier DR
Disease models & mechanisms 2019 Jun 17;12(6)
Disease models & mechanisms 2019 Jun 17;12(6)
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
Han X, Li Y, Xu Y, Zhao X, Zhang Y, Yang X, Wang Y, Zhao R, Anderson GJ, Zhao Y, Nie G
Nature communications 2018 Aug 23;9(1):3390
Nature communications 2018 Aug 23;9(1):3390
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HT-1080 cells were subjected to SDS PAGE followed by western blot with 10875-1-AP(SERPINH1 antibody) at dilution of 1:100
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HSP47 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HSP47. This antibody recognizes human,mouse,rat antigen. The HSP47 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
