orb148127

antibody from Biorbyt

Targeting: SERPINH1 CBP1, CBP2, colligen, HSP47, SERPINH2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

orb148127

Provider

Biorbyt

Product name

HSP47 Antibody: Biotin

Antibody type

Monoclonal

Description

Mouse monoclonal to Hsp47 (Biotin). Hsp47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of Hsp47 around fibrotic lesions. The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since Hsp47 binds a single substrate. Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils..

Reactivity

Human

Host

Mouse

Conjugate

Biotin

Isotype

IgG

Antibody clone number

1C4-1A6

Vial size

200 ug

Concentration

1 mg/ml

Storage

Conjugated antibodies should be stored according to the product label