orb148132

antibody from Biorbyt
Targeting: SERPINH1 CBP1, CBP2, colligen, HSP47, SERPINH2
Provider product page for orb148132
Western blot
Immunocytochemistry

Antibody data

Product number
orb148132 - Provider product page
Provider
Biorbyt
Product name
HSP47 antibody
Antibody type
Monoclonal
Description
Mouse monoclonal to Hsp47 (RPE). Hsp47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of Hsp47 around fibrotic lesions. The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since Hsp47 binds a single substrate. Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils..
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
1C4-1A6
Vial size
200 ug
Concentration
1 mg/ml
Storage
Conjugated antibodies should be stored at 4°C
SERPINH1 protein structure - orb148132 shown in red.