Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 13981-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13981-1-AP, RRID:AB_2233481
- Product name
- IGFBP1 antibody
- Antibody type
- Polyclonal
- Description
- IGFBP1 antibody (Cat. #13981-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references IGFBP1 is One of 10 Metabolic Factors Predicting Recurrence Free Survival in Gastric Cancer and Promotes Cancer Progression via ZFX-IGFBP1 Axis.
Deciphering m6A signatures in hepatocellular carcinoma: Single-cell insights, immune landscape, and the protective role of IGFBP3.
NR5A1 Deficiency Leads to Decidualization Dysregulation of Stromal Cells and Recurrent Spontaneous Abortion During Early Pregnancy.
IGFBP1 orchestrates metabolic reprogramming to drive clear cell renal cell carcinoma progression through NR1H4-mediated lipid homeostasis disruption.
Impaired decidualization and angiogenesis in eutopic endometrium of endometriosis: insights from in vitro models†.
Prioritization of potential drug targets for diabetic kidney disease using integrative omics data mining and causal inference.
The study of JAZF1-mediated apoptosis of decidual stromal cells by activating the NF-κB signaling pathway in spontaneous preterm birth.
PYK2 promotes cell proliferation and epithelial-mesenchymal transition in endometriosis by phosphorylating Snail1.
High androgen level during controlled ovarian stimulation cycle impairs endometrial receptivity in PCOS patients.
IGFBP1 promotes the proliferation and migration of lung adenocarcinoma cells through the PPARα pathway.
Histone MARylation regulates lipid metabolism in colorectal cancer by promoting IGFBP1 methylation.
Metformin enhances epithelial cell growth inhibition via the protein kinase-insulin-like growth factor binding protein-1 pathway.
An integrated analysis of prognostic mRNA signature in early- and progressive-stage gastric adenocarcinoma.
Increased expression of prokineticin 2 and its receptor in endometrium of recurrent implantation failure patients decreased the expression of MMP9 important for decidualization.
Effects of natural 24-epibrassinolide on inducing apoptosis and restricting metabolism in hepatocarcinoma cells.
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
Molecular profiling of thymoma with myasthenia gravis: Risk factors of developing myasthenia gravis in thymoma patients.
Effects of Levonorgestrel and progesterone on Oviductal physiology in mammals.
IGFBP1 Involved in the Decreased Birth Weight Due to Fetal High Estrogen Exposure in Mice.
Differences in IGF axis-related proteins in amniotic fluid of trisomy 21 and trisomy 18 using a multiple reaction monitoring approach.
Stathmin is key in reversion of doxorubicin resistance by arsenic trioxide in osteosarcoma cells.
Liu H, Huang Y, Fu G, Lei B, Liu K
OncoTargets and therapy 2025;18:717-732
OncoTargets and therapy 2025;18:717-732
Deciphering m6A signatures in hepatocellular carcinoma: Single-cell insights, immune landscape, and the protective role of IGFBP3.
Chen S, Liu J, Zhang S, Zhao L, Zhang J, Han P, Zhang Q, Liu Y, Wang F, Li J
Environmental toxicology 2025 Mar;40(3):367-383
Environmental toxicology 2025 Mar;40(3):367-383
NR5A1 Deficiency Leads to Decidualization Dysregulation of Stromal Cells and Recurrent Spontaneous Abortion During Early Pregnancy.
Dai J, Jiang H, Liu D, Dong Z, Hu L, He F, Yu T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70752
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70752
IGFBP1 orchestrates metabolic reprogramming to drive clear cell renal cell carcinoma progression through NR1H4-mediated lipid homeostasis disruption.
Sun Y, Hao Y, Peng F, Ling H, Sun K, Qiu J, Yang T, Zhao L, Xia Q
Cancer cell international 2025 Jul 28;25(1):284
Cancer cell international 2025 Jul 28;25(1):284
Impaired decidualization and angiogenesis in eutopic endometrium of endometriosis: insights from in vitro models†.
Qin R, Zhong X, Lin J, Li C, Liu X, Qin A, Zheng F
Biology of reproduction 2025 Dec 16;113(6):1539-1548
Biology of reproduction 2025 Dec 16;113(6):1539-1548
Prioritization of potential drug targets for diabetic kidney disease using integrative omics data mining and causal inference.
Zhang J, Peng J, Yu C, Ning Y, Lin W, Ni M, Xie Q, Yang C, Liang H, Lin M
Journal of pharmaceutical analysis 2025 Aug;15(8):101265
Journal of pharmaceutical analysis 2025 Aug;15(8):101265
The study of JAZF1-mediated apoptosis of decidual stromal cells by activating the NF-κB signaling pathway in spontaneous preterm birth.
Gong MQ, Hu YY, Zhang YQ, Wang XD
BMC pregnancy and childbirth 2025 Aug 27;25(1):891
BMC pregnancy and childbirth 2025 Aug 27;25(1):891
PYK2 promotes cell proliferation and epithelial-mesenchymal transition in endometriosis by phosphorylating Snail1.
Liu L, Liu L, Yue C, Du S, Liu J, Yu Z
Molecular medicine (Cambridge, Mass.) 2025 Apr 27;31(1):155
Molecular medicine (Cambridge, Mass.) 2025 Apr 27;31(1):155
High androgen level during controlled ovarian stimulation cycle impairs endometrial receptivity in PCOS patients.
Wei SY, Zhang JL, Guan HQ, Cai JJ, Jiang XF, Wang H, Wu DD, Lin XH
Scientific reports 2024 Oct 4;14(1):23100
Scientific reports 2024 Oct 4;14(1):23100
IGFBP1 promotes the proliferation and migration of lung adenocarcinoma cells through the PPARα pathway.
Li Y, Yang X, Han T, Zhou J, Liu Y, Guo J, Liu Z, Bai Y, Xing Y, Ding X, Wu J, Hu D
Translational oncology 2024 Nov;49:102095
Translational oncology 2024 Nov;49:102095
Histone MARylation regulates lipid metabolism in colorectal cancer by promoting IGFBP1 methylation.
Wang C, Tang Y, Zhang S, Li M, Li Q, Xiao M, Yang L, Wang Y
Experimental cell research 2024 Nov 1;443(1):114308
Experimental cell research 2024 Nov 1;443(1):114308
Metformin enhances epithelial cell growth inhibition via the protein kinase-insulin-like growth factor binding protein-1 pathway.
Shao X, Li C, Liang J, Changzhong L
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2024 Dec;44(1):2321651
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2024 Dec;44(1):2321651
An integrated analysis of prognostic mRNA signature in early- and progressive-stage gastric adenocarcinoma.
Hong X, Zhuang K, Xu N, Wang J, Liu Y, Tang S, Zhao J, Huang Z
Frontiers in molecular biosciences 2022;9:1022056
Frontiers in molecular biosciences 2022;9:1022056
Increased expression of prokineticin 2 and its receptor in endometrium of recurrent implantation failure patients decreased the expression of MMP9 important for decidualization.
Zhai J, Ma L, Chang Z, Yu T
Reproductive biology and endocrinology : RB&E 2022 May 2;20(1):76
Reproductive biology and endocrinology : RB&E 2022 May 2;20(1):76
Effects of natural 24-epibrassinolide on inducing apoptosis and restricting metabolism in hepatocarcinoma cells.
Zhou H, Zhuang W, Huang H, Ma N, Lei J, Jin G, Wu S, Zhou S, Zhao X, Lan L, Xia H, Shangguan F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154428
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154428
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
Zhou L, Zhang C, Yang X, Liu L, Hu J, Hou Y, Tao H, Sugimura H, Chen Z, Wang L, Chen K
Clinical and translational medicine 2021 Jun;11(6):e449
Clinical and translational medicine 2021 Jun;11(6):e449
Molecular profiling of thymoma with myasthenia gravis: Risk factors of developing myasthenia gravis in thymoma patients.
Lee MC, Hsiao TH, Chuang HN, Lee LW, Chi PL, Tsai HM, Mao CL, Hsu CP
Lung cancer (Amsterdam, Netherlands) 2020 Jan;139:157-164
Lung cancer (Amsterdam, Netherlands) 2020 Jan;139:157-164
Effects of Levonorgestrel and progesterone on Oviductal physiology in mammals.
Li C, Zhang HY, Liang Y, Xia W, Zhu Q, Zhang D, Huang Z, Liang GL, Xue RH, Qi H, He XQ, Yuan JJ, Tan YJ, Huang HF, Zhang J
Reproductive biology and endocrinology : RB&E 2018 Jun 20;16(1):59
Reproductive biology and endocrinology : RB&E 2018 Jun 20;16(1):59
IGFBP1 Involved in the Decreased Birth Weight Due to Fetal High Estrogen Exposure in Mice.
Jin M, Lv PP, Yu TT, Shen JM, Feng C, Huang HF
Biology of reproduction 2016 Nov;95(5):96
Biology of reproduction 2016 Nov;95(5):96
Differences in IGF axis-related proteins in amniotic fluid of trisomy 21 and trisomy 18 using a multiple reaction monitoring approach.
Lai G, Zhang Y, Wang L, Zhang B, Zheng G, Wang X, Zhao X, Gao H, Zhao Y
Prenatal diagnosis 2014 Dec;34(12):1146-52
Prenatal diagnosis 2014 Dec;34(12):1146-52
Stathmin is key in reversion of doxorubicin resistance by arsenic trioxide in osteosarcoma cells.
Feng T, Qiao G, Feng L, Qi W, Huang Y, Yao Y, Shen Z
Molecular medicine reports 2014 Dec;10(6):2985-92
Molecular medicine reports 2014 Dec;10(6):2985-92
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human placenta tissue were subjected to SDS PAGE followed by western blot with 13981-1-AP(IGFBP1 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The IGFBP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human IGFBP1. This antibody recognizes human antigen. The IGFBP1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.