MAB1240

antibody from R&D Systems

Targeting: IGFBP1 AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12

Western blot (Data presented on provider website)

Antibody Data

Product number

MAB1240

Provider

R&D Systems

Product name

Mouse IGFBP-1 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects mouse IGFBP-1 in direct ELISAs and Western blots. In Western blots, weak cross-reactivity with recombinant mouse (rm) IGFBP-5 is observed and no cross-reactivity with recombinant human (rh) IGFBP-1, rmIGFBP-2, rmIGFBP-3, rhIGFBP-4, rmIGFBP-6, or rhIGFBP-7 is observed.

Reactivity

Mouse

Host

Rat

Conjugate

Unconjugated

Antigen sequence

P47876


Isotype

IgG

Antibody clone number

176110

Vial size

500 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model.

Parrella E, Maxim T, Maialetti F, Zhang L, Wan J, Wei M, Cohen P, Fontana L, Longo VD
Aging cell 2013 Apr;12(2):257-68

---

Endocrine actions of myostatin: systemic regulation of the IGF and IGF binding protein axis.

Williams NG, Interlichia JP, Jackson MF, Hwang D, Cohen P, Rodgers BD
Endocrinology 2011 Jan;152(1):172-80

---

Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation.

Yamada PM, Mehta HH, Hwang D, Roos KP, Hevener AL, Lee KW
Endocrinology 2010 Dec;151(12):5741-50