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Other assayAntibody data
- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Other assay [1]
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- Product number
- P420A - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- IL-1 alpha Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- P420A targets IL-1 alpha in WB applications and shows reactivity with Bovine, and Human samples.
- Concentration
- 1.0 mg/mL
Submitted references Potential role of proinflammatory cytokines in the pathogenetic mechanisms of vascular lesions in goats naturally infected with bluetongue virus serotype 1.
Distinct expression of interleukin-1α, interleukin-1β, and interleukin-1 receptor antagonist in testicular tissues and cells from human biopsies with normal and abnormal histology.
Cross-reactivity of anti-human, anti-porcine and anti-bovine cytokine antibodies with cetacean tissues.
Expression of genes associated with immunity in the endometrium of cattle with disparate postpartum uterine disease and fertility.
Changes in macrophages in spleen and lymph nodes during acute African swine fever: expression of cytokines.
Changes in macrophages in spleen and lymph nodes during acute African swine fever: expression of cytokines.
Macrophage- and neutrophil-dominant arthritis in human IL-1 alpha transgenic mice.
Costimulation via TCR and IL-1 receptor reveals a novel IL-1alpha-mediated autocrine pathway of Th2 cell proliferation.
Entamoeba histolytica trophozoites induce an inflammatory cytokine response by cultured human cells through the paracrine action of cytolytically released interleukin-1 alpha.
Induction of IL-3 and granulocyte-macrophage colony-stimulating factor by substance P in bone marrow cells is partially mediated through the release of IL-1 and IL-6.
Sánchez-Cordón PJ, Pedrera M, Risalde MA, Molina V, Rodríguez-Sánchez B, Núñez A, Sánchez-Vizcaíno JM, Gómez-Villamandos JC
Transboundary and emerging diseases 2013 Jun;60(3):252-62
Transboundary and emerging diseases 2013 Jun;60(3):252-62
Distinct expression of interleukin-1α, interleukin-1β, and interleukin-1 receptor antagonist in testicular tissues and cells from human biopsies with normal and abnormal histology.
Abu Elheija M, Dyomin V, Ganaiem M, Lunenfeld E, Vardy NS, Huleihel M
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2011 Apr;31(4):401-8
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2011 Apr;31(4):401-8
Cross-reactivity of anti-human, anti-porcine and anti-bovine cytokine antibodies with cetacean tissues.
Jaber JR, Pérez J, Zafra R, Herráez P, Rodríguez F, Arbelo M, de los Monteros AE, Fernández A
Journal of comparative pathology 2010 Jul;143(1):45-51
Journal of comparative pathology 2010 Jul;143(1):45-51
Expression of genes associated with immunity in the endometrium of cattle with disparate postpartum uterine disease and fertility.
Herath S, Lilly ST, Santos NR, Gilbert RO, Goetze L, Bryant CE, White JO, Cronin J, Sheldon IM
Reproductive biology and endocrinology : RB&E 2009 May 29;7:55
Reproductive biology and endocrinology : RB&E 2009 May 29;7:55
Changes in macrophages in spleen and lymph nodes during acute African swine fever: expression of cytokines.
Salguero FJ, Ruiz-Villamor E, Bautista MJ, Sánchez-Cordón PJ, Carrasco L, Gómez-Villamandos JC
Veterinary immunology and immunopathology 2002 Nov;90(1-2):11-22
Veterinary immunology and immunopathology 2002 Nov;90(1-2):11-22
Changes in macrophages in spleen and lymph nodes during acute African swine fever: expression of cytokines.
Salguero FJ, Ruiz-Villamor E, Bautista MJ, Sánchez-Cordón PJ, Carrasco L, Gómez-Villamandos JC
Veterinary immunology and immunopathology 2002 Nov;90(1-2):11-22
Veterinary immunology and immunopathology 2002 Nov;90(1-2):11-22
Macrophage- and neutrophil-dominant arthritis in human IL-1 alpha transgenic mice.
Niki Y, Yamada H, Seki S, Kikuchi T, Takaishi H, Toyama Y, Fujikawa K, Tada N
The Journal of clinical investigation 2001 May;107(9):1127-35
The Journal of clinical investigation 2001 May;107(9):1127-35
Costimulation via TCR and IL-1 receptor reveals a novel IL-1alpha-mediated autocrine pathway of Th2 cell proliferation.
Huber M, Beuscher HU, Rohwer P, Kurrle R, Röllinghoff M, Lohoff M
Journal of immunology (Baltimore, Md. : 1950) 1998 May 1;160(9):4242-7
Journal of immunology (Baltimore, Md. : 1950) 1998 May 1;160(9):4242-7
Entamoeba histolytica trophozoites induce an inflammatory cytokine response by cultured human cells through the paracrine action of cytolytically released interleukin-1 alpha.
Eckmann L, Reed SL, Smith JR, Kagnoff MF
The Journal of clinical investigation 1995 Sep;96(3):1269-79
The Journal of clinical investigation 1995 Sep;96(3):1269-79
Induction of IL-3 and granulocyte-macrophage colony-stimulating factor by substance P in bone marrow cells is partially mediated through the release of IL-1 and IL-6.
Rameshwar P, Ganea D, Gascón P
Journal of immunology (Baltimore, Md. : 1950) 1994 Apr 15;152(8):4044-54
Journal of immunology (Baltimore, Md. : 1950) 1994 Apr 15;152(8):4044-54
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 8 Endometrial expression of TNF, IL-6, TLR4, IL-10, IL-1 alpha, IL-1 beta and cytokeratin protein . Immunohistochemical localization of TNF, IL-6, TLR4, IL-10, IL-1 alpha, IL-1 beta and cytokeratin in the endometrium of postpartum cows. 5 mum sections of Formalin-fixed paraffin-embedded endometrial biopsies were examined using the primary antibodies described in Methods with Alexa Fluor 555 secondary antibodies, mounted with DAPI Vectashield. Representative images of TNF, IL-6, TLR4, IL-10, IL-1 alpha, IL-1 beta and cytokeratin immunoreactive protein and an isotype IgG control in endometrial tissue from animals week 1 post partum are shown. The scale bar is 100 mum.
