RA0390

antibody from Oursmab

Targeting: IL4R CD124

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0390

Provider

Oursmab

Product name

Dupilumab (Biosimilar Reference Antibody) (IL4R)

Antibody type

Monoclonal

Description

Dupilumab is a fully human monoclonal antibody used to treat multiple type 2 inflammatory diseases. Marketed under the brand name Dupixent?, it is approved for conditions including moderate-to-severe atopic dermatitis, asthma with an eosinophilic phenotype or oral corticosteroid dependence, chronic rhinosinusitis with nasal polyps (CRSwNP), eosinophilic esophagitis (EoE), and prurigo nodularis. It works by inhibiting a key shared signaling pathway for interleukin-4 (IL-4) and interleukin-13 (IL-13), two central cytokines driving type 2 inflammation. Administered via subcutaneous injection, it has become a cornerstone biologic for these chronic conditions.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.