MAB2471

antibody from R&D Systems

Targeting: IL15 IL-15, MGC9721

Western blot (Recommended by provider)

Flow cytometry (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

MAB2471

Provider

R&D Systems

Product name

Anti-Human IL-15 Monoclonal Antibody (Clone 34559)

Antibody type

Monoclonal

Antigen

E. coli-derived recombinant human IL-15, Asn49-Ser162

Description

Protein A or G purified from ascites

Reactivity

Human

Host

Mouse

Antigen sequence

P40933


Isotype

IgG

Vial size

500 µg

References

Submitted references

Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis.

Touil H, Kobert A, Lebeurrier N, Rieger A, Saikali P, Lambert C, Fawaz L, Moore CS, Prat A, Gommerman J, Antel JP, Itoyama Y, Nakashima I, Bar-Or A, Canadian B Cell Team in MS.
Journal of neuroinflammation 2018 Apr 19;15(1):114

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MiR-205/YAP1 in Activated Fibroblasts of Breast Tumor Promotes VEGF-independent Angiogenesis through STAT3 Signaling.

Du YE, Tu G, Yang G, Li G, Yang D, Lang L, Xi L, Sun K, Chen Y, Shu K, Liao H, Liu M, Hou Y
Theranostics 2017;7(16):3972-3988

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Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use.

Van den Bergh JMJ, Smits ELJM, Versteven M, De Reu H, Berneman ZN, Van Tendeloo VFI, Lion E
Journal of immunology research 2017;2017:1975902

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A Refractory Celiac Patient Successfully Treated With Mesenchymal Stem Cell Infusions.

Ciccocioppo R, Gallia A, Avanzini MA, Betti E, Picone C, Vanoli A, Paganini C, Biagi F, Maccario R, Corazza GR
Mayo Clinic proceedings 2016 Jun;91(6):812-9

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Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner.

Anguille S, Van Acker HH, Van den Bergh J, Willemen Y, Goossens H, Van Tendeloo VF, Smits EL, Berneman ZN, Lion E
PloS one 2015;10(5):e0123340

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Type I IFNs and IL-18 regulate the antiviral response of primary human γδ T cells against dendritic cells infected with Dengue virus.

Tsai CY, Liong KH, Gunalan MG, Li N, Lim DS, Fisher DA, MacAry PA, Leo YS, Wong SC, Puan KJ, Wong SB
Journal of immunology (Baltimore, Md. : 1950) 2015 Apr 15;194(8):3890-900

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IL15RA drives antagonistic mechanisms of cancer development and immune control in lymphocyte-enriched triple-negative breast cancers.

Marra P, Mathew S, Grigoriadis A, Wu Y, Kyle-Cezar F, Watkins J, Rashid M, De Rinaldis E, Hessey S, Gazinska P, Hayday A, Tutt A
Cancer research 2014 Sep 1;74(17):4908-21

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Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection.

Muntasell A, Magri G, Pende D, Angulo A, López-Botet M
Blood 2010 Jun 24;115(25):5170-9

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Juxtacrine function of interleukin-15/interleukin-15 receptor system in tumour derived human B-cell lines.

Tsukamoto K, Huang YC, Dorsey WC, Carns B, Sharma V
Clinical and experimental immunology 2006 Dec;146(3):559-66

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Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis.

Ong PY, Hamid QA, Travers JB, Strickland I, Al Kerithy M, Boguniewicz M, Leung DY
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 1;168(1):505-10

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Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis.

Ong PY, Hamid QA, Travers JB, Strickland I, Al Kerithy M, Boguniewicz M, Leung DY
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 1;168(1):505-10