ABIN360116

antibody from antibodies-online

Targeting: IRAK1 IRAK, pelle

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN360116

Provider

antibodies-online

Product name

anti-Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) (C-Term) antibody

Antibody type

Polyclonal

Description

Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Reactivity

Human

Host

Rabbit

Epitope

C-Term

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex.

Jiang Z, Johnson HJ, Nie H, Qin J, Bird TA, Li X
The Journal of biological chemistry 2003 Mar 28;278(13):10952-6

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Characterization of Pellino2, a substrate of IRAK1 and IRAK4.

Strelow A, Kollewe C, Wesche H
FEBS letters 2003 Jul 17;547(1-3):157-61

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Pellino3, a novel member of the Pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein.

Jensen LE, Whitehead AS
Journal of immunology (Baltimore, Md. : 1950) 2003 Aug 1;171(3):1500-6

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IRAK: a kinase associated with the interleukin-1 receptor.

Cao Z, Henzel WJ, Gao X
Science (New York, N.Y.) 1996 Feb 23;271(5252):1128-31