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- Antigen structure
- References [29]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10023-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10023-1-AP, RRID:AB_2281669
- Product name
- JNK antibody
- Antibody type
- Polyclonal
- Description
- JNK antibody (Cat. #10023-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Acupuncture Alleviates Chronic Ischemic White Matter Injury in SHR Rats via JNK-NMDAR Circuit.
Network pharmacology and experimental validation of effects of total saponins extracted from Abrus cantoniensis Hance on acetaminophen-induced liver injury.
TYRO3 protects podocyte via JNK/c-jun-P53 pathway.
Young Sca-1(+) bone marrow stem cell-derived exosomes preserve visual function via the miR-150-5p/MEKK3/JNK/c-Jun pathway to reduce M1 microglial polarization.
EGCG Attenuates CA1 Neuronal Death by Regulating GPx1, NF-κB S536 Phosphorylation and Mitochondrial Dynamics in the Rat Hippocampus following Status Epilepticus.
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
BCATc inhibitor 2 ameliorated mitochondrial dysfunction and apoptosis in oleic acid-induced non-alcoholic fatty liver disease model.
Excretory/secretory proteins inhibit host immune responses by downregulating the TLR4/NF-κB/MAPKs signaling pathway: A possible mechanism of immune evasion in parasitic nematode Haemonchus contortus.
Astragalin mitigates inflammatory osteolysis by negatively modulating osteoclastogenesis via ROS and MAPK signaling pathway.
Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation.
Isovitexin Inhibits Ginkgolic Acids-Induced Inflammation Through Downregulating SHP2 Activation.
Overexpression of FOXA2 attenuates cigarette smoke-induced cellular senescence and lung inflammation through inhibition of the p38 and Erk1/2 MAPK pathways.
PM2.5 exposure induces reproductive injury through IRE1/JNK/autophagy signaling in male rats.
A new prognosis prediction model combining TNM stage with MAP2K4 and JNK in postoperative pancreatic cancer patients.
The anti-rotavirus effect of baicalin via the gluconeogenesis-related p-JNK-PDK1-AKT-SIK2 signaling pathway.
Synergistic effect of Huyang Yangkun Formula and embryonic stem cells on 4-vinylcyclohexene diepoxide induced premature ovarian insufficiency in mice.
Phenolic Glycosides from the Roots of Ficus hirta Vahl. and Their Antineuroinflammatory Activities.
Upregulation of OTUD7B (Cezanne) Promotes Tumor Progression via AKT/VEGF Pathway in Lung Squamous Carcinoma and Adenocarcinoma.
Blockade of AMPA Receptor Regulates Mitochondrial Dynamics by Modulating ERK1/2 and PP1/PP2A-Mediated DRP1-S616 Phosphorylations in the Normal Rat Hippocampus.
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
The Regional Specific Alterations in BBB Permeability are Relevant to the Differential Responses of 67-kDa LR Expression in Endothelial Cells and Astrocytes Following Status Epilepticus.
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis.
CDDO-Me Selectively Attenuates CA1 Neuronal Death Induced by Status Epilepticus via Facilitating Mitochondrial Fission Independent of LONP1.
Melatonin reprogramming of gut microbiota improves lipid dysmetabolism in high-fat diet-fed mice.
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
TRPC6-mediated ERK1/2 phosphorylation prevents dentate granule cell degeneration via inhibiting mitochondrial elongation.
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression.
Focal adhesion kinase antisense oligodeoxynucleotides inhibit human pulmonary artery smooth muscle cells proliferation and promote human pulmonary artery smooth muscle cells apoptosis.
Dong A, Gao Z, Wang H, Wu R, Wang W, Jin X, Ji Y, Yang F, Zhu T, Jiang Z, Xu Y, Guo J, Ji L
Molecular neurobiology 2024 Jun;61(6):3144-3160
Molecular neurobiology 2024 Jun;61(6):3144-3160
Network pharmacology and experimental validation of effects of total saponins extracted from Abrus cantoniensis Hance on acetaminophen-induced liver injury.
He J, Chen L, Wang P, Cen B, Li J, Wei Y, Yao X, Xu Z
Journal of ethnopharmacology 2024 Apr 24;324:117740
Journal of ethnopharmacology 2024 Apr 24;324:117740
TYRO3 protects podocyte via JNK/c-jun-P53 pathway.
Zhang L, Jiang S, Shi J, Xu X, Wang L, Zhai X, Hou Q, Qin W, Chen Z
Archives of biochemistry and biophysics 2023 May 1;739:109578
Archives of biochemistry and biophysics 2023 May 1;739:109578
Young Sca-1(+) bone marrow stem cell-derived exosomes preserve visual function via the miR-150-5p/MEKK3/JNK/c-Jun pathway to reduce M1 microglial polarization.
Wang Y, Qin WY, Wang Q, Liu XN, Li XH, Ye XQ, Bai Y, Zhang Y, Liu P, Wang XL, Zhou YH, Yuan HP, Shao ZB
Journal of nanobiotechnology 2023 Jun 15;21(1):194
Journal of nanobiotechnology 2023 Jun 15;21(1):194
EGCG Attenuates CA1 Neuronal Death by Regulating GPx1, NF-κB S536 Phosphorylation and Mitochondrial Dynamics in the Rat Hippocampus following Status Epilepticus.
Kim JE, Kim TH, Kang TC
Antioxidants (Basel, Switzerland) 2023 Apr 20;12(4)
Antioxidants (Basel, Switzerland) 2023 Apr 20;12(4)
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Jiang XL, Tai H, Xiao XS, Zhang SY, Cui SC, Qi SB, Hu DD, Zhang LN, Kuang JS, Meng XS, Li SM
Frontiers in endocrinology 2022;13:962154
Frontiers in endocrinology 2022;13:962154
BCATc inhibitor 2 ameliorated mitochondrial dysfunction and apoptosis in oleic acid-induced non-alcoholic fatty liver disease model.
Lu Z, Sun GF, Pan XA, Qu XH, Yang P, Chen ZP, Han XJ, Wang T
Frontiers in pharmacology 2022;13:1025551
Frontiers in pharmacology 2022;13:1025551
Excretory/secretory proteins inhibit host immune responses by downregulating the TLR4/NF-κB/MAPKs signaling pathway: A possible mechanism of immune evasion in parasitic nematode Haemonchus contortus.
Wen Z, Zhang Y, Feng J, Aimulajiang K, Aleem MT, Lu M, Xu L, Song X, Li X, Yan R
Frontiers in immunology 2022;13:1013159
Frontiers in immunology 2022;13:1013159
Astragalin mitigates inflammatory osteolysis by negatively modulating osteoclastogenesis via ROS and MAPK signaling pathway.
Xing F, Geng L, Guan H, Liu D, Li Y, Zeng L, Chen Y, Tian R, Li Z, Cao R, Zhao Y, Yan P, Qiang H, Kong N, Wang K, Yang P
International immunopharmacology 2022 Nov;112:109278
International immunopharmacology 2022 Nov;112:109278
Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation.
Byts N, Sharma S, Malm T, Kaakinen M, Korhonen P, Jaakkonen L, Keuters M, Huuskonen M, Pietilä I, Koistinaho J, Koivunen P, Myllyharju J
The Journal of biological chemistry 2022 Mar;298(3):101721
The Journal of biological chemistry 2022 Mar;298(3):101721
Isovitexin Inhibits Ginkgolic Acids-Induced Inflammation Through Downregulating SHP2 Activation.
Zhang Y, Qi Z, Wang W, Wang L, Cao F, Zhao L, Fang X
Frontiers in pharmacology 2021;12:630320
Frontiers in pharmacology 2021;12:630320
Overexpression of FOXA2 attenuates cigarette smoke-induced cellular senescence and lung inflammation through inhibition of the p38 and Erk1/2 MAPK pathways.
Tao Y, Sun Y, Wu B, Xu D, Yang J, Gu L, Du C
International immunopharmacology 2021 May;94:107427
International immunopharmacology 2021 May;94:107427
PM2.5 exposure induces reproductive injury through IRE1/JNK/autophagy signaling in male rats.
Yang Y, Feng Y, Huang H, Cui L, Li F
Ecotoxicology and environmental safety 2021 Mar 15;211:111924
Ecotoxicology and environmental safety 2021 Mar 15;211:111924
A new prognosis prediction model combining TNM stage with MAP2K4 and JNK in postoperative pancreatic cancer patients.
Liu XD, Zhang ZW, Wu HW, Liang ZY
Pathology, research and practice 2021 Jan;217:153313
Pathology, research and practice 2021 Jan;217:153313
The anti-rotavirus effect of baicalin via the gluconeogenesis-related p-JNK-PDK1-AKT-SIK2 signaling pathway.
Song L, Zhong P, Zhu X, Zhou R, Gao M, Lan Q, Chen J, Chen Y, Zhao W
European journal of pharmacology 2021 Apr 15;897:173927
European journal of pharmacology 2021 Apr 15;897:173927
Synergistic effect of Huyang Yangkun Formula and embryonic stem cells on 4-vinylcyclohexene diepoxide induced premature ovarian insufficiency in mice.
Li M, Xie L, Li Y, Liu J, Nie G, Yang H
Chinese medicine 2020;15:83
Chinese medicine 2020;15:83
Phenolic Glycosides from the Roots of Ficus hirta Vahl. and Their Antineuroinflammatory Activities.
Ye X, Tian W, Wang G, Zhang X, Zhou M, Zeng D, Liu X, Yao X, Zhang Y, Chen H
Journal of agricultural and food chemistry 2020 Apr 8;68(14):4196-4204
Journal of agricultural and food chemistry 2020 Apr 8;68(14):4196-4204
Upregulation of OTUD7B (Cezanne) Promotes Tumor Progression via AKT/VEGF Pathway in Lung Squamous Carcinoma and Adenocarcinoma.
Lin DD, Shen Y, Qiao S, Liu WW, Zheng L, Wang YN, Cui N, Wang YF, Zhao S, Shi JH
Frontiers in oncology 2019;9:862
Frontiers in oncology 2019;9:862
Blockade of AMPA Receptor Regulates Mitochondrial Dynamics by Modulating ERK1/2 and PP1/PP2A-Mediated DRP1-S616 Phosphorylations in the Normal Rat Hippocampus.
Kim JE, Choi HC, Song HK, Kang TC
Frontiers in cellular neuroscience 2019;13:179
Frontiers in cellular neuroscience 2019;13:179
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Wang X, Adegoke EO, Ma M, Huang F, Zhang H, Adeniran SO, Zheng P, Zhang G
Theriogenology 2019 Oct 15;138:84-93
Theriogenology 2019 Oct 15;138:84-93
The Regional Specific Alterations in BBB Permeability are Relevant to the Differential Responses of 67-kDa LR Expression in Endothelial Cells and Astrocytes Following Status Epilepticus.
Park H, Kang TC
International journal of molecular sciences 2019 Nov 29;20(23)
International journal of molecular sciences 2019 Nov 29;20(23)
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis.
Wei Y, Meng M, Tian Z, Xie F, Yin Q, Dai C, Wang J, Zhang Q, Liu Y, Liu C, Yan F, Jiang F, Guo X
Pharmacological research 2019 Mar;141:114-122
Pharmacological research 2019 Mar;141:114-122
CDDO-Me Selectively Attenuates CA1 Neuronal Death Induced by Status Epilepticus via Facilitating Mitochondrial Fission Independent of LONP1.
Kim JE, Park H, Choi SH, Kong MJ, Kang TC
Cells 2019 Aug 5;8(8)
Cells 2019 Aug 5;8(8)
Melatonin reprogramming of gut microbiota improves lipid dysmetabolism in high-fat diet-fed mice.
Yin J, Li Y, Han H, Chen S, Gao J, Liu G, Wu X, Deng J, Yu Q, Huang X, Fang R, Li T, Reiter RJ, Zhang D, Zhu C, Zhu G, Ren W, Yin Y
Journal of pineal research 2018 Nov;65(4):e12524
Journal of pineal research 2018 Nov;65(4):e12524
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, Liu H, Wang Y, Xu L, Dong Z
Neurochemical research 2018 Jun;43(6):1283-1296
Neurochemical research 2018 Jun;43(6):1283-1296
TRPC6-mediated ERK1/2 phosphorylation prevents dentate granule cell degeneration via inhibiting mitochondrial elongation.
Ko AR, Kang TC
Neuropharmacology 2017 Jul 15;121:120-129
Neuropharmacology 2017 Jul 15;121:120-129
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Xu D, Su C, Song X, Shi Q, Fu J, Hu L, Xia X, Song E, Song Y
Chemical research in toxicology 2015 Jun 15;28(6):1326-37
Chemical research in toxicology 2015 Jun 15;28(6):1326-37
13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression.
Su CC, Chen JY, Din ZH, Su JH, Yang ZY, Chen YJ, Wang RY, Wu YJ
Marine drugs 2014 Oct 23;12(10):5295-315
Marine drugs 2014 Oct 23;12(10):5295-315
Focal adhesion kinase antisense oligodeoxynucleotides inhibit human pulmonary artery smooth muscle cells proliferation and promote human pulmonary artery smooth muscle cells apoptosis.
Lin CL, Zhang ZX, Xu YJ, Ni W, Chen SX
Chinese medical journal 2005 Jan 5;118(1):20-6
Chinese medical journal 2005 Jan 5;118(1):20-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10023-1-AP(JNK antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The JNK antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human JNK. This antibody recognizes human, mouse, rat antigen. The JNK antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
