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- Antigen structure
- References [123]
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- Product number
- 51151-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#51151-1-AP, RRID:AB_2140710
- Product name
- JNK antibody
- Antibody type
- Polyclonal
- Description
- JNK antibody (Cat. #51151-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Nanoparticulate bioceramic putty suppresses osteoclastogenesis and inflammatory bone loss in mice via inhibition of TRAF6-mediated signalling pathways: A laboratory investigation.
Extracellular ATP (eATP) inhibits the progression of endometriosis and enhances the immune function of macrophages.
Resveratrol alleviates heat-stress-induced impairment of the jejunal mucosa through TLR4/MAPK signaling pathway in black-boned chicken.
Bioinformatics and experimental studies jointly reveal that Sacubitril Valsartan improves myocardial oxidative stress and inflammation by regulating the MAPK signaling pathway to treat chemotherapy related cardiotoxicity.
CP41, a novel curcumin analogue, induces apoptosis in endometrial cancer cells by activating the H3F3A/ proteasome-MAPK signaling pathway and enhancing oxidative stress.
HBI-8000 improves heart failure with preserved ejection fraction via the TGF-β1/MAPK signalling pathway.
A mechanism study of DUSP1 in inhibiting malignant progression of endometrial carcinoma by regulating ERK/AP-1 axis and dephosphorylation of EPHA2.
Investigation of anti-diabetic effect of a novel coenzyme Q10 derivative.
Proteogenomics of different urothelial bladder cancer stages reveals distinct molecular features for papillary cancer and carcinoma in situ.
Angiotensin-(1-7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-κB and MAPK pathways.
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Quantitative Proteomics Based on iTRAQ Reveal that Nitidine Chloride Induces Apoptosis by Activating JNK/c-Jun Signaling in Hepatocellular Carcinoma Cells.
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
RNA m6A reader IGF2BP3 promotes metastasis of triple-negative breast cancer via SLIT2 repression.
Losartan attenuates sepsis-induced cardiomyopathy by regulating macrophage polarization via TLR4-mediated NF-κB and MAPK signaling.
Amentoflavone attenuates Listeria monocytogenes pathogenicity through an LLO-dependent mechanism.
Endoplasmic reticulum stress mediates parathyroid hormone-induced apoptosis in vascular smooth muscle cells.
Kaempferol-Driven Inhibition of Listeriolysin O Pore Formation and Inflammation Suppresses Listeria monocytogenes Infection.
RHOV promotes lung adenocarcinoma cell growth and metastasis through JNK/c-Jun pathway.
Ras-Related C3 Botulinum Toxin Substrate 1 Combining With the Mixed Lineage Kinase 3- Mitogen-Activated Protein Kinase 7- c-Jun N-Terminal Kinase Signaling Module Accelerates Diabetic Nephropathy.
The EIF4A3/CASC2/RORA Feedback Loop Regulates the Aggressive Phenotype in Glioblastomas.
Rubioncolin C, a natural naphthohydroquinone dimer isolated from Rubia yunnanensis, inhibits the proliferation and metastasis by inducing ROS-mediated apoptotic and autophagic cell death in triple-negative breast cancer cells.
RABL2A-CCDC34 Axis Promotes Sorafenib Resistance in Hepatocellular Carcinoma.
Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.
Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells.
NDUFA4L2 in smooth muscle promotes vascular remodeling in hypoxic pulmonary arterial hypertension.
MiR-24 Protects Cardiomyocytes Against Hypoxia/Reoxygenation-Induced Injury Through Regulating Mitogen-Activated Protein Kinase 14.
Antiprolactinoma Effect of Hordenine by Inhibiting MAPK Signaling Pathway Activation in Rats.
25-Hydroxycholesterol protects against myocardial ischemia-reperfusion injury via inhibiting PARP activity.
Li-Dan-He-Ji Improves Infantile Cholestasis Hepatopathy Through Inhibiting Calcium-Sensing Receptor-Mediated Hepatocyte Apoptosis.
A Natural Dietary Flavone Myricetin as an α-Hemolysin Inhibitor for Controlling Staphylococcus aureus Infection.
NOD2/c-Jun NH(2)-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
Daidzein ameliorates LPS-induced hepatocyte injury by inhibiting inflammation and oxidative stress.
The anti-inflammatory potential of protein-bound anthocyanin compounds from purple sweet potato in LPS-induced RAW264.7 macrophages.
Enhancement of anti-acne effect of Scutellaria baicalensis extract by fermentation with symbiotic fungus Penicillium decumbens.
Functionalized graphene oxide against U251 glioma cells and its molecular mechanism.
Icariside II suppresses cervical cancer cell migration through JNK modulated matrix metalloproteinase-2/9 inhibition in vitro and in vivo.
Strontium-substituted sub-micron bioactive glasses inhibit ostoclastogenesis through suppression of RANKL-induced signaling pathway.
miR-22 represses osteoblast viability with ESR1 presenting a direct target and indirectly inactivating p38 MAPK/JNK signaling.
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload.
Discovery of novel TNNI3K inhibitor suppresses pyroptosis and apoptosis in murine myocardial infarction injury.
Spondin 2 promotes the proliferation, migration and invasion of gastric cancer cells.
VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer.
Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8(+)CD28(-) T cells.
Mincle/Syk Signalling Promotes Intestinal Mucosal Inflammation Through Induction of Macrophage Pyroptosis in Crohn's Disease.
Transplanting Rac1-silenced bone marrow mesenchymal stem cells promote neurological function recovery in TBI mice.
Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.
The protective effects of β-sitosterol and vermicularin from Thamnolia vermicularis (Sw.) Ach. against skin aging in vitro.
Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blocking the TLR4/NF-κB/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response.
[JNK/c-Jun signaling pathway mediates arginine vasopressin neuron regeneration by promoting cytoskeleton reconstruction in rats with electrical lesions of the pituitary stalk].
Activation of mitogen-activated protein kinases in satellite glial cells of the trigeminal ganglion contributes to substance P-mediated inflammatory pain.
Regulation of circadian rhythms by NEAT1 mediated TMAO-induced endothelial proliferation: A protective role of asparagus extract.
Tricetin protects against 6-OHDA-induced neurotoxicity in Parkinson's disease model by activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway.
PM(2.5) upregulates rat mesenteric arteries 5-HT(2A) receptor via inflammatory-mediated mitogen-activated protein kinases signaling pathway.
NT3(P75-2) gene-modified bone mesenchymal stem cells improve neurological function recovery in mouse TBI model.
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway.
Chipmunk Brain Is Resistant to Injury from Deep Hypothermic Circulatory Arrest During Cardiopulmonary Bypass.
Elucidating dosage-effect relationship of different efficacy of rhubarb in constipation model rats by factor analysis.
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Isosteviol Sodium Protects Neural Cells Against Hypoxia-Induced Apoptosis Through Inhibiting MAPK and NF-κB Pathways.
Grape Seed Proanthocyanidins Induce Autophagy and Modulate Survivin in HepG2 Cells and Inhibit Xenograft Tumor Growth in Vivo.
Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather broilers.
The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.
The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPARα Activation.
Effect of artemisinin and neurectomy of pterygoid canal in ovalbumin-induced allergic rhinitis mouse model.
XRCC1 rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer.
JNK/STAT signalling pathway is involved in fluoride-induced follicular developmental dysplasia in female mice.
New insights into meningitic Escherichia coli infection of brain microvascular endothelial cells from quantitative proteomics analysis.
Paris saponin VII induces cell cycle arrest and apoptosis by regulating Akt/MAPK pathway and inhibition of P-glycoprotein in K562/ADR cells.
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
KDM3A inhibition attenuates high concentration insulin‑induced vascular smooth muscle cell injury by suppressing MAPK/NF‑κB pathways.
Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen-Glucose Deprivation and Reperfusion.
NF-κB and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.
MicroRNA-24 regulates vascular remodeling via inhibiting PDGF-BB pathway in diabetic rat model.
Oxymatrine attenuates lipopolysaccharide-induced acute lung injury by activating the epithelial sodium channel and suppressing the JNK signaling pathway.
Correlation of TGN-020 with the analgesic effects via ERK pathway activation after chronic constriction injury.
OAMDP, a novel podophyllotoxin derivative, induces apoptosis, cell cycle arrest and autophagy in hepatoma HepG2 cells.
Benzyl sulforaphane is superior to sulforaphane in inhibiting the Akt/MAPK and activating the Nrf2/ARE signalling pathways in HepG2 cells.
Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis.
A CREB1/miR-433 reciprocal feedback loop modulates proliferation and metastasis in colorectal cancer.
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.
Spiroplasma eriocheiris induces mouse 3T6-Swiss albino cell apoptosis that associated with the infection mechanism.
Dectin-1 is essential for IL-1β production through JNK activation and apoptosis in Aspergillus fumigatus keratitis.
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways.
Polyphyllin I induces G2/M phase arrest and apoptosis in U251 human glioma cells via mitochondrial dysfunction and the JNK signaling pathway.
The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis.
TGF-β Down-regulates Apolipoprotein M Expression through the TAK-1-JNK-c-Jun Pathway in HepG2 Cells.
HnRNP-L mediates bladder cancer progression by inhibiting apoptotic signaling and enhancing MAPK signaling pathways.
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
Vitamin K2 Induces Mitochondria-Related Apoptosis in Human Bladder Cancer Cells via ROS and JNK/p38 MAPK Signal Pathways.
Wnt-11 overexpression promoting the invasion of cervical cancer cells.
Rhizoma Coptidis alkaloids alleviate hyperlipidemia in B6 mice by modulating gut microbiota and bile acid pathways.
Low molecular weight fucoidan modulates P-selectin and alleviates diabetic nephropathy.
Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Resveratrol Increases Anti-Proliferative Activity of Bestatin Through Downregulating P-Glycoprotein Expression Via Inhibiting PI3K/Akt/mTOR Pathway in K562/ADR Cells.
Recombinant adeno-associated virus-delivered anginex inhibits angiogenesis and growth of HUVECs by regulating the Akt, JNK and NF-κB signaling pathways.
Ghrelin protects against palmitic acid or lipopolysaccharide-induced hepatocyte apoptosis through inhibition of MAPKs/iNOS and restoration of Akt/eNOS pathways.
A new steroidal saponin, furotrilliumoside from Trillium tschonoskii inhibits lipopolysaccharide-induced inflammation in Raw264.7 cells by targeting PI3K/Akt, MARK and Nrf2/HO-1 pathways.
Paper-based microreactor array for rapid screening of cell signaling cascades.
Inhibitive effects of 15-deoxy-Δ(12),(14)-prostaglandin J2 on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis.
Necrostatin-1 reduces intestinal inflammation and colitis-associated tumorigenesis in mice.
RhNRG-1β Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway.
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Effect of Fructus Ligustri Lucidi on osteoblastic like cell-line MC3T3-E1.
Sialic acid rescues repurified lipopolysaccharide-induced acute renal failure via inhibiting TLR4/PKC/gp91-mediated endoplasmic reticulum stress, apoptosis, autophagy, and pyroptosis signaling.
Inhibition of TROY promotes OPC differentiation and increases therapeutic efficacy of OPC graft for spinal cord injury.
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis.
Induction of apoptosis by sinulariolide from soft coral through mitochondrial-related and p38MAPK pathways on human bladder carcinoma cells.
Wang Z, Zhang J, Sun X, Yu J, Liu B, Peng B, Wang L, Yang J, Zhu L
International endodontic journal 2024 Jun;57(6):682-699
International endodontic journal 2024 Jun;57(6):682-699
Extracellular ATP (eATP) inhibits the progression of endometriosis and enhances the immune function of macrophages.
Zhou L, Cai E, Liu H, Cheng H, Ye X, Zhu H, Chang X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166895
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166895
Resveratrol alleviates heat-stress-induced impairment of the jejunal mucosa through TLR4/MAPK signaling pathway in black-boned chicken.
Liu L, Gong X, Zhang X, Zhang D, Tang Y, Liu J, Li Y, Pan D
Poultry science 2024 Jan;103(1):103242
Poultry science 2024 Jan;103(1):103242
Bioinformatics and experimental studies jointly reveal that Sacubitril Valsartan improves myocardial oxidative stress and inflammation by regulating the MAPK signaling pathway to treat chemotherapy related cardiotoxicity.
Shi H, Lu H, Zheng Y, Pu P, Wei L, Hu D, Tang H, Wang L
Biochemical and biophysical research communications 2024 Jan 1;690:149244
Biochemical and biophysical research communications 2024 Jan 1;690:149244
CP41, a novel curcumin analogue, induces apoptosis in endometrial cancer cells by activating the H3F3A/ proteasome-MAPK signaling pathway and enhancing oxidative stress.
Zhang MJ, Shi M, Yu Y, Wang H, Ou R, Ge RS
Life sciences 2024 Feb 1;338:122406
Life sciences 2024 Feb 1;338:122406
HBI-8000 improves heart failure with preserved ejection fraction via the TGF-β1/MAPK signalling pathway.
Tian J, Li W, Zeng L, Li Y, Du J, Li Y, Li B, Su G
Journal of cellular and molecular medicine 2024 Apr;28(7):e18238
Journal of cellular and molecular medicine 2024 Apr;28(7):e18238
A mechanism study of DUSP1 in inhibiting malignant progression of endometrial carcinoma by regulating ERK/AP-1 axis and dephosphorylation of EPHA2.
Lei S, He X, Yang X, Gu X, He Y, Wang J
Journal of Cancer 2023;14(4):634-645
Journal of Cancer 2023;14(4):634-645
Investigation of anti-diabetic effect of a novel coenzyme Q10 derivative.
Tan X, Yang X, Xu X, Peng Y, Li X, Deng Y, Zhang X, Qiu W, Wu D, Ruan Y, Zhi C
Frontiers in chemistry 2023;11:1280999
Frontiers in chemistry 2023;11:1280999
Proteogenomics of different urothelial bladder cancer stages reveals distinct molecular features for papillary cancer and carcinoma in situ.
Yao Z, Xu N, Shang G, Wang H, Tao H, Wang Y, Qin Z, Tan S, Feng J, Zhu J, Ma F, Tian S, Zhang Q, Qu Y, Hou J, Guo J, Zhao J, Hou Y, Ding C
Nature communications 2023 Sep 13;14(1):5670
Nature communications 2023 Sep 13;14(1):5670
Angiotensin-(1-7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-κB and MAPK pathways.
Chen XS, Cui JR, Meng XL, Wang SH, Wei W, Gao YL, Shou ST, Liu YC, Chai YF
Journal of translational medicine 2023 Jan 2;21(1):2
Journal of translational medicine 2023 Jan 2;21(1):2
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Shen Y, Teng L, Qu Y, Huang Y, Peng Y, Tang M, Fu Q
Inflammation 2023 Apr;46(2):655-678
Inflammation 2023 Apr;46(2):655-678
Quantitative Proteomics Based on iTRAQ Reveal that Nitidine Chloride Induces Apoptosis by Activating JNK/c-Jun Signaling in Hepatocellular Carcinoma Cells.
Chen S, Liao Y, Lv J, Hou H, Feng J
Planta medica 2022 Oct;88(13):1233-1244
Planta medica 2022 Oct;88(13):1233-1244
Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell.
Gong X, He Y, Yang D, Yang S, Li J, Zhao H, Chen Q, Ren Q, Zhang B
Bioorganic chemistry 2022 Oct;127:105939
Bioorganic chemistry 2022 Oct;127:105939
RNA m6A reader IGF2BP3 promotes metastasis of triple-negative breast cancer via SLIT2 repression.
Jiang T, He X, Zhao Z, Zhang X, Wang T, Jia L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22618
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22618
Losartan attenuates sepsis-induced cardiomyopathy by regulating macrophage polarization via TLR4-mediated NF-κB and MAPK signaling.
Chen XS, Wang SH, Liu CY, Gao YL, Meng XL, Wei W, Shou ST, Liu YC, Chai YF
Pharmacological research 2022 Nov;185:106473
Pharmacological research 2022 Nov;185:106473
Amentoflavone attenuates Listeria monocytogenes pathogenicity through an LLO-dependent mechanism.
Tingting W, Tianqi F, Xinyu W, Can Z, Xue S, Xuming D, Jianfeng W
British journal of pharmacology 2022 Jul;179(14):3839-3858
British journal of pharmacology 2022 Jul;179(14):3839-3858
Endoplasmic reticulum stress mediates parathyroid hormone-induced apoptosis in vascular smooth muscle cells.
Duan S, Chen X, Liu Y, Guo W, Liu W
Renal failure 2022 Dec;44(1):126-136
Renal failure 2022 Dec;44(1):126-136
Kaempferol-Driven Inhibition of Listeriolysin O Pore Formation and Inflammation Suppresses Listeria monocytogenes Infection.
Wang T, Liu B, Zhang C, Fang T, Ding Y, Song G, Zhang S, Shi L, Deng X, Wang J
Microbiology spectrum 2022 Aug 31;10(4):e0181022
Microbiology spectrum 2022 Aug 31;10(4):e0181022
RHOV promotes lung adenocarcinoma cell growth and metastasis through JNK/c-Jun pathway.
Zhang D, Jiang Q, Ge X, Shi Y, Ye T, Mi Y, Xie T, Li Q, Ye Q
International journal of biological sciences 2021;17(10):2622-2632
International journal of biological sciences 2021;17(10):2622-2632
Ras-Related C3 Botulinum Toxin Substrate 1 Combining With the Mixed Lineage Kinase 3- Mitogen-Activated Protein Kinase 7- c-Jun N-Terminal Kinase Signaling Module Accelerates Diabetic Nephropathy.
Ying C, Dai J, Fan G, Zhou Z, Gan T, Zhang Y, Song Y, Zhou X
Frontiers in physiology 2021;12:679166
Frontiers in physiology 2021;12:679166
The EIF4A3/CASC2/RORA Feedback Loop Regulates the Aggressive Phenotype in Glioblastomas.
Zhao J, Jiang Y, Chen L, Ma Y, Zhang H, Zhou J, Li H, Jing Z
Frontiers in oncology 2021;11:699933
Frontiers in oncology 2021;11:699933
Rubioncolin C, a natural naphthohydroquinone dimer isolated from Rubia yunnanensis, inhibits the proliferation and metastasis by inducing ROS-mediated apoptotic and autophagic cell death in triple-negative breast cancer cells.
Li L, Wang J, Feng L, Fan J, Wang J, Tan N, Wang Z
Journal of ethnopharmacology 2021 Sep 15;277:114184
Journal of ethnopharmacology 2021 Sep 15;277:114184
RABL2A-CCDC34 Axis Promotes Sorafenib Resistance in Hepatocellular Carcinoma.
Zhou M, Chen X, Bai H, Sun Y, Zhang Z, Li S, Wang X, Zeng M
DNA and cell biology 2021 Nov;40(11):1418-1427
DNA and cell biology 2021 Nov;40(11):1418-1427
Asenapine maleate inhibits angiotensin II-induced proliferation and activation of cardiac fibroblasts via the ROS/TGFβ1/MAPK signaling pathway.
Wu HH, Meng TT, Chen JM, Meng FL, Wang SY, Liu RH, Chen JN, Ning B, Li Y, Su GH
Biochemical and biophysical research communications 2021 May 14;553:172-179
Biochemical and biophysical research communications 2021 May 14;553:172-179
Melatonin ameliorates cypermethrin-induced impairments by regulating oxidative stress, DNA damage and apoptosis in porcine Sertoli cells.
Li J, Sun BX, Wang DL, Liu Y, Qi JJ, Nie XW, Bai CY, Zhang JB, Liang S
Theriogenology 2021 Jun;167:67-76
Theriogenology 2021 Jun;167:67-76
NDUFA4L2 in smooth muscle promotes vascular remodeling in hypoxic pulmonary arterial hypertension.
Liu Y, Nie X, Zhu J, Wang T, Li Y, Wang Q, Sun Z
Journal of cellular and molecular medicine 2021 Jan;25(2):1221-1237
Journal of cellular and molecular medicine 2021 Jan;25(2):1221-1237
MiR-24 Protects Cardiomyocytes Against Hypoxia/Reoxygenation-Induced Injury Through Regulating Mitogen-Activated Protein Kinase 14.
Qin SQ, Zhang ZS, Wang XY, Shi JZ, Yang XB
International heart journal 2020;61(4):806-814
International heart journal 2020;61(4):806-814
Antiprolactinoma Effect of Hordenine by Inhibiting MAPK Signaling Pathway Activation in Rats.
Wang X, Guo RZ, Ma L, Ding QY, Meng JH, Chen YG, Wu JH
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3107290
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3107290
25-Hydroxycholesterol protects against myocardial ischemia-reperfusion injury via inhibiting PARP activity.
Lv S, Ju C, Peng J, Liang M, Zhu F, Wang C, Huang K, Cheng M, Zhang F
International journal of biological sciences 2020;16(2):298-308
International journal of biological sciences 2020;16(2):298-308
Li-Dan-He-Ji Improves Infantile Cholestasis Hepatopathy Through Inhibiting Calcium-Sensing Receptor-Mediated Hepatocyte Apoptosis.
Qin H, Zhang LL, Xiong XL, Jiang ZX, Xiao CP, Zhang LL, Wang YJ, Wu YT, Qiu YY, Zhou LS, Yan SQ
Frontiers in pharmacology 2020;11:156
Frontiers in pharmacology 2020;11:156
A Natural Dietary Flavone Myricetin as an α-Hemolysin Inhibitor for Controlling Staphylococcus aureus Infection.
Wang T, Zhang P, Lv H, Deng X, Wang J
Frontiers in cellular and infection microbiology 2020;10:330
Frontiers in cellular and infection microbiology 2020;10:330
NOD2/c-Jun NH(2)-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
Luo H, Wu X, Xu Z, Hao X, Wang Y, Li M
Journal of bacteriology 2020 Sep 23;202(20)
Journal of bacteriology 2020 Sep 23;202(20)
Daidzein ameliorates LPS-induced hepatocyte injury by inhibiting inflammation and oxidative stress.
Yu Z, Yang L, Deng S, Liang M
European journal of pharmacology 2020 Oct 15;885:173399
European journal of pharmacology 2020 Oct 15;885:173399
The anti-inflammatory potential of protein-bound anthocyanin compounds from purple sweet potato in LPS-induced RAW264.7 macrophages.
Jiang T, Zhou J, Liu W, Tao W, He J, Jin W, Guo H, Yang N, Li Y
Food research international (Ottawa, Ont.) 2020 Nov;137:109647
Food research international (Ottawa, Ont.) 2020 Nov;137:109647
Enhancement of anti-acne effect of Scutellaria baicalensis extract by fermentation with symbiotic fungus Penicillium decumbens.
Zhu X, Mao Y, Guo M, Yu H, Hao L, Hua Q, Lu Z, Hong M, An F
Journal of bioscience and bioengineering 2020 Nov;130(5):457-463
Journal of bioscience and bioengineering 2020 Nov;130(5):457-463
Functionalized graphene oxide against U251 glioma cells and its molecular mechanism.
Wang P, Wang X, Tang Q, Chen H, Zhang Q, Jiang H, Wang Z
Materials science & engineering. C, Materials for biological applications 2020 Nov;116:111187
Materials science & engineering. C, Materials for biological applications 2020 Nov;116:111187
Icariside II suppresses cervical cancer cell migration through JNK modulated matrix metalloproteinase-2/9 inhibition in vitro and in vivo.
Sun YS, Thakur K, Hu F, Cespedes-Acuña CL, Zhang JG, Wei ZJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110013
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110013
Strontium-substituted sub-micron bioactive glasses inhibit ostoclastogenesis through suppression of RANKL-induced signaling pathway.
Huang D, Zhao F, Gao W, Chen X, Guo Z, Zhang W
Regenerative biomaterials 2020 Jun;7(3):303-311
Regenerative biomaterials 2020 Jun;7(3):303-311
miR-22 represses osteoblast viability with ESR1 presenting a direct target and indirectly inactivating p38 MAPK/JNK signaling.
Chen GH, Zhang XL, Chen H, Lin H, Wu HJ, Lin H, Huang GZ
The journal of gene medicine 2020 Jun;22(6):e3174
The journal of gene medicine 2020 Jun;22(6):e3174
BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer.
Liu JZ, Hu YL, Feng Y, Jiang Y, Guo YB, Liu YF, Chen X, Yang JL, Chen YY, Mao QS, Xue WJ
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Journal of experimental & clinical cancer research : CR 2020 Jun 30;39(1):123
Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload.
Wang J, Deng B, Liu Q, Huang Y, Chen W, Li J, Zhou Z, Zhang L, Liang B, He J, Chen Z, Yan C, Yang Z, Xian S, Wang L
Cell death & disease 2020 Jul 24;11(7):574
Cell death & disease 2020 Jul 24;11(7):574
Discovery of novel TNNI3K inhibitor suppresses pyroptosis and apoptosis in murine myocardial infarction injury.
Pang H, Wang N, Chai J, Wang X, Zhang Y, Bi Z, Wu W, He G
European journal of medicinal chemistry 2020 Jul 1;197:112314
European journal of medicinal chemistry 2020 Jul 1;197:112314
Spondin 2 promotes the proliferation, migration and invasion of gastric cancer cells.
Lu H, Feng Y, Hu Y, Guo Y, Liu Y, Mao Q, Xue W
Journal of cellular and molecular medicine 2020 Jan;24(1):98-113
Journal of cellular and molecular medicine 2020 Jan;24(1):98-113
VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer.
Chen Y, Liu Z, Wang H, Tang Z, Liu Y, Liang Z, Deng X, Zhao M, Fu Q, Li L, Cai H, Xie W, Fang W
International journal of cancer 2020 Jan 15;146(2):496-509
International journal of cancer 2020 Jan 15;146(2):496-509
Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathway-regulated autophagy and upregulating the circulating of CD8(+)CD28(-) T cells.
Yin N, Wu C, Qiu J, Zhang Y, Bo L, Xu Y, Shi M, Zhu S, Yang G, Mao C
Stem cell research & therapy 2020 Feb 4;11(1):49
Stem cell research & therapy 2020 Feb 4;11(1):49
Mincle/Syk Signalling Promotes Intestinal Mucosal Inflammation Through Induction of Macrophage Pyroptosis in Crohn's Disease.
Gong W, Zheng T, Guo K, Fang M, Xie H, Li W, Tang Q, Hong Z, Ren H, Gu G, Wang G, Wu X, Zhao Y, Ren J
Journal of Crohn's & colitis 2020 Dec 2;14(12):1734-1747
Journal of Crohn's & colitis 2020 Dec 2;14(12):1734-1747
Transplanting Rac1-silenced bone marrow mesenchymal stem cells promote neurological function recovery in TBI mice.
Huang D, Siaw-Debrah F, Wang H, Ye S, Wang K, Wu K, Zhang Y, Wang H, Yao C, Chen J, Yan L, Zhang CL, Zhuge Q, Yang J
Aging 2020 Dec 19;13(2):2822-2850
Aging 2020 Dec 19;13(2):2822-2850
Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.
Li JM, Yang F, Li J, Yuan WQ, Wang H, Luo YQ
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 7;26:e925298
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 7;26:e925298
The protective effects of β-sitosterol and vermicularin from Thamnolia vermicularis (Sw.) Ach. against skin aging in vitro.
Haiyuan YU, Shen X, Liu D, Hong M, Lu Y
Anais da Academia Brasileira de Ciencias 2019;91(4):e20181088
Anais da Academia Brasileira de Ciencias 2019;91(4):e20181088
Protective Effect of Methane-Rich Saline on Acetic Acid-Induced Ulcerative Colitis via Blocking the TLR4/NF-κB/MAPK Pathway and Promoting IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response.
Wang G, Xu B, Shi F, Du M, Li Y, Yu T, Chen L
Oxidative medicine and cellular longevity 2019;2019:7850324
Oxidative medicine and cellular longevity 2019;2019:7850324
[JNK/c-Jun signaling pathway mediates arginine vasopressin neuron regeneration by promoting cytoskeleton reconstruction in rats with electrical lesions of the pituitary stalk].
Li K, Feng Z, Ou Y, Zhou M, Peng J, Gong H, Wu G, Liu Y, Qi S
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Sep 30;39(9):1099-1106
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Sep 30;39(9):1099-1106
Activation of mitogen-activated protein kinases in satellite glial cells of the trigeminal ganglion contributes to substance P-mediated inflammatory pain.
Zhang Y, Song N, Liu F, Lin J, Liu M, Huang C, Liao D, Zhou C, Wang H, Shen J
International journal of oral science 2019 Sep 10;11(3):24
International journal of oral science 2019 Sep 10;11(3):24
Regulation of circadian rhythms by NEAT1 mediated TMAO-induced endothelial proliferation: A protective role of asparagus extract.
Wu X, Chen L, Zeb F, Huang Y, An J, Ren J, Yang F, Feng Q
Experimental cell research 2019 Sep 1;382(1):111451
Experimental cell research 2019 Sep 1;382(1):111451
Tricetin protects against 6-OHDA-induced neurotoxicity in Parkinson's disease model by activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway.
Ren J, Yuan L, Wang W, Zhang M, Wang Q, Li S, Zhang L, Hu K
Toxicology and applied pharmacology 2019 Sep 1;378:114617
Toxicology and applied pharmacology 2019 Sep 1;378:114617
PM(2.5) upregulates rat mesenteric arteries 5-HT(2A) receptor via inflammatory-mediated mitogen-activated protein kinases signaling pathway.
Wang R, Cao L, Shen ZX, Cao YX, Yu J
Environmental toxicology 2019 Oct;34(10):1094-1104
Environmental toxicology 2019 Oct;34(10):1094-1104
NT3(P75-2) gene-modified bone mesenchymal stem cells improve neurological function recovery in mouse TBI model.
Wu K, Huang D, Zhu C, Kasanga EA, Zhang Y, Yu E, Zhang H, Ni Z, Ye S, Zhang C, Hu J, Zhuge Q, Yang J
Stem cell research & therapy 2019 Oct 24;10(1):311
Stem cell research & therapy 2019 Oct 24;10(1):311
Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs.
Jia YN, Peng YL, Zhao YP, Cheng XF, Zhou Y, Chai CL, Zeng LS, Pan MH, Xu L
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
Journal of agricultural and food chemistry 2019 May 15;67(19):5521-5529
Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway.
Wu YJ, Su TR, Dai GF, Su JH, Liu CI
Marine drugs 2019 May 13;17(5)
Marine drugs 2019 May 13;17(5)
Chipmunk Brain Is Resistant to Injury from Deep Hypothermic Circulatory Arrest During Cardiopulmonary Bypass.
Jiang X, Gu T, Liu Y, Gao S, Shi E, Zhang G
Therapeutic hypothermia and temperature management 2019 Jun;9(2):118-127
Therapeutic hypothermia and temperature management 2019 Jun;9(2):118-127
Elucidating dosage-effect relationship of different efficacy of rhubarb in constipation model rats by factor analysis.
Chen JQ, Li DW, Chen YY, Tao HJ, Pu ZJ, Zhang J, Tan YJ, Shi XQ, Yue SJ, Zhou GS, Tang YP, Duan JA
Journal of ethnopharmacology 2019 Jun 28;238:111868
Journal of ethnopharmacology 2019 Jun 28;238:111868
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Wang Y, He G, Tang H, Shi Y, Kang X, Lyu J, Zhu M, Zhou M, Yang M, Mu M, Chen W, Zhou B, Zhang J, Tang K
Cell proliferation 2019 Jul;52(4):e12650
Cell proliferation 2019 Jul;52(4):e12650
Isosteviol Sodium Protects Neural Cells Against Hypoxia-Induced Apoptosis Through Inhibiting MAPK and NF-κB Pathways.
Zhong KL, Lu MY, Liu F, Mei Y, Zhang XJ, Zhang H, Zan J, Sun XO, Tan W
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jan;28(1):175-184
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 Jan;28(1):175-184
Grape Seed Proanthocyanidins Induce Autophagy and Modulate Survivin in HepG2 Cells and Inhibit Xenograft Tumor Growth in Vivo.
Wang L, Huang W, Zhan J
Nutrients 2019 Dec 6;11(12)
Nutrients 2019 Dec 6;11(12)
Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather broilers.
He S, Yu Q, He Y, Hu R, Xia S, He J
Poultry science 2019 Dec 1;98(12):6378-6387
Poultry science 2019 Dec 1;98(12):6378-6387
The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.
Yu Q, Liu T, Li S, Feng J, Wu L, Wang W, Chen K, Xia Y, Niu P, Xu L, Wang F, Dai W, Zhou Y, Guo C
Mediators of inflammation 2018;2018:4032484
Mediators of inflammation 2018;2018:4032484
The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPARα Activation.
Wang W, Chen K, Xia Y, Mo W, Wang F, Dai W, Niu P
PPAR research 2018;2018:3180396
PPAR research 2018;2018:3180396
Effect of artemisinin and neurectomy of pterygoid canal in ovalbumin-induced allergic rhinitis mouse model.
Li J, Wang B, Luo Y, Bian Y, Wang R
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 2018;14:22
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 2018;14:22
XRCC1 rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer.
Li Q, Ma R, Zhang M
OncoTargets and therapy 2018;11:8435-8444
OncoTargets and therapy 2018;11:8435-8444
JNK/STAT signalling pathway is involved in fluoride-induced follicular developmental dysplasia in female mice.
Zhao WP, Wang HW, Liu J, Tan PP, Lin L, Zhou BH
Chemosphere 2018 Oct;209:88-95
Chemosphere 2018 Oct;209:88-95
New insights into meningitic Escherichia coli infection of brain microvascular endothelial cells from quantitative proteomics analysis.
Liu WT, Lv YJ, Yang RC, Fu JY, Liu L, Wang H, Cao Q, Tan C, Chen HC, Wang XR
Journal of neuroinflammation 2018 Oct 19;15(1):291
Journal of neuroinflammation 2018 Oct 19;15(1):291
Paris saponin VII induces cell cycle arrest and apoptosis by regulating Akt/MAPK pathway and inhibition of P-glycoprotein in K562/ADR cells.
Yan T, Hu G, Wang A, Sun X, Yu X, Jia J
Phytotherapy research : PTR 2018 May;32(5):898-907
Phytotherapy research : PTR 2018 May;32(5):898-907
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus.
Liu H, Liu Q, Hua L, Pan J
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
Acta biochimica et biophysica Sinica 2018 May 1;50(5):499-506
KDM3A inhibition attenuates high concentration insulin‑induced vascular smooth muscle cell injury by suppressing MAPK/NF‑κB pathways.
Zhang BF, Jiang H, Chen J, Guo X, Hu Q, Yang S
International journal of molecular medicine 2018 Mar;41(3):1265-1274
International journal of molecular medicine 2018 Mar;41(3):1265-1274
Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen-Glucose Deprivation and Reperfusion.
Zhao P, Chang RY, Liu N, Wang J, Zhou R, Qi X, Liu Y, Ma L, Niu Y, Sun T, Li YX, He YP, Yu JQ
Cellular and molecular neurobiology 2018 Mar;38(2):529-540
Cellular and molecular neurobiology 2018 Mar;38(2):529-540
NF-κB and JNK mediated apoptosis and G(0)/G(1) arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis.
Zeng GZ, Wang Z, Zhao LM, Fan JT, Tan NH
Journal of ethnopharmacology 2018 Jun 28;220:220-227
Journal of ethnopharmacology 2018 Jun 28;220:220-227
MicroRNA-24 regulates vascular remodeling via inhibiting PDGF-BB pathway in diabetic rat model.
Yang J, Zeng P, Yang J, Liu X, Ding J, Wang H, Chen L
Gene 2018 Jun 15;659:67-76
Gene 2018 Jun 15;659:67-76
Oxymatrine attenuates lipopolysaccharide-induced acute lung injury by activating the epithelial sodium channel and suppressing the JNK signaling pathway.
Jin B, Jin H
Experimental animals 2018 Jul 30;67(3):337-347
Experimental animals 2018 Jul 30;67(3):337-347
Correlation of TGN-020 with the analgesic effects via ERK pathway activation after chronic constriction injury.
Zhao L, Li D, Liu N, Liu L, Zhang Z, Gao C, Kawano H, Zhou FY, Li HP
Molecular pain 2018 Jan-Dec;14:1744806918796057
Molecular pain 2018 Jan-Dec;14:1744806918796057
OAMDP, a novel podophyllotoxin derivative, induces apoptosis, cell cycle arrest and autophagy in hepatoma HepG2 cells.
Ren J, Liu Y, Li L, Zhao Y, Li Z, Wu C, Chen L, Hu K
Cell biology international 2018 Feb;42(2):194-204
Cell biology international 2018 Feb;42(2):194-204
Benzyl sulforaphane is superior to sulforaphane in inhibiting the Akt/MAPK and activating the Nrf2/ARE signalling pathways in HepG2 cells.
Ren J, Yuan L, Wang Y, Chen G, Hu K
The Journal of pharmacy and pharmacology 2018 Dec;70(12):1643-1653
The Journal of pharmacy and pharmacology 2018 Dec;70(12):1643-1653
Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis.
Zhao W, Che C, Liu K, Zhang J, Jiang N, Yuan K, Zhao G
Cornea 2018 Dec;37(12):1579-1585
Cornea 2018 Dec;37(12):1579-1585
A CREB1/miR-433 reciprocal feedback loop modulates proliferation and metastasis in colorectal cancer.
Yan L, You WQ, Sheng NQ, Gong JF, Hu LD, Tan GW, Chen HQ, Wang ZG
Aging 2018 Dec 6;10(12):3774-3793
Aging 2018 Dec 6;10(12):3774-3793
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Xiang L, Xu X, Zhang S, Cai D, Dai X
Free radical biology & medicine 2018 Aug 20;124:205-213
Free radical biology & medicine 2018 Aug 20;124:205-213
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Geng W, Qin F, Ren J, Xiao S, Wang A
Experimental cell research 2018 Aug 15;369(2):243-250
Experimental cell research 2018 Aug 15;369(2):243-250
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Feng J, Zhang Q, Mo W, Wu L, Li S, Li J, Liu T, Xu S, Fan X, Guo C
Drug design, development and therapy 2017;11:1989-2006
Drug design, development and therapy 2017;11:1989-2006
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
Chen HB, Luo CD, Liang JL, Zhang ZB, Lin GS, Wu JZ, Li CL, Tan LH, Yang XB, Su ZR, Xie JH, Zeng HF
European journal of pharmacology 2017 Sep 15;811:222-231
European journal of pharmacology 2017 Sep 15;811:222-231
Effect of Subcellular Translocation of Protein Disulfide Isomerase on Tetrachlorobenzoquinone-Induced Signaling Shift from Endoplasmic Reticulum Stress to Apoptosis.
Liu Z, Wang Y, Wang Y, Dong W, Xia X, Song E, Song Y
Chemical research in toxicology 2017 Oct 16;30(10):1804-1814
Chemical research in toxicology 2017 Oct 16;30(10):1804-1814
Spiroplasma eriocheiris induces mouse 3T6-Swiss albino cell apoptosis that associated with the infection mechanism.
Hou L, Gu W, Zhu H, Yao W, Wang W, Meng Q
Molecular immunology 2017 Nov;91:75-85
Molecular immunology 2017 Nov;91:75-85
Dectin-1 is essential for IL-1β production through JNK activation and apoptosis in Aspergillus fumigatus keratitis.
Yuan K, Zhao G, Che C, Li C, Lin J, Zhu G, He K
International immunopharmacology 2017 Nov;52:168-175
International immunopharmacology 2017 Nov;52:168-175
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Xu S, Niu P, Chen K, Xia Y, Yu Q, Liu N, Li J, Li S, Wu L, Feng J, Wang W, Lu X, Liu T, Wang F, Dai W, Fan X, Mo W, Xu L, Guo C
Scientific reports 2017 Nov 9;7(1):15175
Scientific reports 2017 Nov 9;7(1):15175
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Gong X, Yang Y, Huang L, Zhang Q, Wan RZ, Zhang P, Zhang B
International immunopharmacology 2017 May;46:124-132
International immunopharmacology 2017 May;46:124-132
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Yang Y, Gong XB, Huang LG, Wang ZX, Wan RZ, Zhang P, Zhang QY, Chen Z, Zhang BS
Oncotarget 2017 May 9;8(19):30723-30733
Oncotarget 2017 May 9;8(19):30723-30733
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
Ren D, Lin D, Alim A, Zheng Q, Yang X
Food & function 2017 Mar 22;8(3):1299-1312
Food & function 2017 Mar 22;8(3):1299-1312
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Tu J, Li W, Zhang Y, Wu X, Song Y, Kang L, Liu W, Wang K, Li S, Hua W, Yang C
Inflammation 2017 Jun;40(3):725-734
Inflammation 2017 Jun;40(3):725-734
The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways.
Lu SY, Wang CY, Jin Y, Meng Q, Liu Q, Liu ZH, Liu KX, Sun HJ, Liu MZ
Scientific reports 2017 Jun 13;7(1):3331
Scientific reports 2017 Jun 13;7(1):3331
Polyphyllin I induces G2/M phase arrest and apoptosis in U251 human glioma cells via mitochondrial dysfunction and the JNK signaling pathway.
Liu J, Zhang Y, Chen L, Yu F, Li X, Dan Tao, Zhao J, Zhou S
Acta biochimica et biophysica Sinica 2017 Jun 1;49(6):479-486
Acta biochimica et biophysica Sinica 2017 Jun 1;49(6):479-486
The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis.
Fan L, Cao X, Yan H, Wang Q, Tian X, Zhang L, He X, Borjihan G, Morigen
Oncotarget 2017 Jul 18;8(29):47250-47268
Oncotarget 2017 Jul 18;8(29):47250-47268
TGF-β Down-regulates Apolipoprotein M Expression through the TAK-1-JNK-c-Jun Pathway in HepG2 Cells.
Ren K, Mo ZC, Liu X, Tang ZL, Jiang Y, Peng XS, Zhang QH, Shi JF, Yi GH
Lipids 2017 Feb;52(2):109-117
Lipids 2017 Feb;52(2):109-117
HnRNP-L mediates bladder cancer progression by inhibiting apoptotic signaling and enhancing MAPK signaling pathways.
Lv D, Wu H, Xing R, Shu F, Lei B, Lei C, Zhou X, Wan B, Yang Y, Zhong L, Mao X, Zou Y
Oncotarget 2017 Feb 21;8(8):13586-13599
Oncotarget 2017 Feb 21;8(8):13586-13599
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Zhao B, Liu L, Mao J, Liu K, Fan W, Liu J, Zhang Z, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning.
Fu J, Xia X, Liu Z, Wang Y, Wang Y, Shi Q, Song X, Song E, Song Y
Toxicology 2017 Apr 15;381:39-50
Toxicology 2017 Apr 15;381:39-50
Vitamin K2 Induces Mitochondria-Related Apoptosis in Human Bladder Cancer Cells via ROS and JNK/p38 MAPK Signal Pathways.
Duan F, Yu Y, Guan R, Xu Z, Liang H, Hong L
PloS one 2016;11(8):e0161886
PloS one 2016;11(8):e0161886
Wnt-11 overexpression promoting the invasion of cervical cancer cells.
Wei H, Wang N, Zhang Y, Wang S, Pang X, Zhang S
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep;37(9):11789-11798
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep;37(9):11789-11798
Rhizoma Coptidis alkaloids alleviate hyperlipidemia in B6 mice by modulating gut microbiota and bile acid pathways.
He K, Hu Y, Ma H, Zou Z, Xiao Y, Yang Y, Feng M, Li X, Ye X
Biochimica et biophysica acta 2016 Sep;1862(9):1696-709
Biochimica et biophysica acta 2016 Sep;1862(9):1696-709
Low molecular weight fucoidan modulates P-selectin and alleviates diabetic nephropathy.
Xu Y, Zhang Q, Luo D, Wang J, Duan D
International journal of biological macromolecules 2016 Oct;91:233-40
International journal of biological macromolecules 2016 Oct;91:233-40
Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.
Xu D, Wang H, Zheng W, Gao Y, Wang M, Zhang Y, Gao Q
International journal of biological macromolecules 2016 Nov;92:30-36
International journal of biological macromolecules 2016 Nov;92:30-36
15d-PGJ2 alleviates ConA-induced acute liver injury in mice by up-regulating HO-1 and reducing hepatic cell autophagy.
Chen K, Li J, Li S, Feng J, Wu L, Liu T, Zhang R, Xu S, Cheng K, Zhou Y, Zhou S, Wang F, Dai W, Xia Y, Lu J, Zhou Y, Guo C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:183-192
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:183-192
Resveratrol Increases Anti-Proliferative Activity of Bestatin Through Downregulating P-Glycoprotein Expression Via Inhibiting PI3K/Akt/mTOR Pathway in K562/ADR Cells.
Wang L, Wang C, Jia Y, Liu Z, Shu X, Liu K
Journal of cellular biochemistry 2016 May;117(5):1233-9
Journal of cellular biochemistry 2016 May;117(5):1233-9
Recombinant adeno-associated virus-delivered anginex inhibits angiogenesis and growth of HUVECs by regulating the Akt, JNK and NF-κB signaling pathways.
Ma K, Wang C, Geng Q, Fan Y, Ning J, Yang H, Dong X, Dong D, Guo Y, Wei X, Li E, Wu Y
Oncology reports 2016 Jun;35(6):3505-13
Oncology reports 2016 Jun;35(6):3505-13
Ghrelin protects against palmitic acid or lipopolysaccharide-induced hepatocyte apoptosis through inhibition of MAPKs/iNOS and restoration of Akt/eNOS pathways.
Mao Y, Wang J, Yu F, Li Z, Li H, Guo C, Fan X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:305-313
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Dec;84:305-313
A new steroidal saponin, furotrilliumoside from Trillium tschonoskii inhibits lipopolysaccharide-induced inflammation in Raw264.7 cells by targeting PI3K/Akt, MARK and Nrf2/HO-1 pathways.
Yan T, Yu X, Sun X, Meng D, Jia JM
Fitoterapia 2016 Dec;115:37-45
Fitoterapia 2016 Dec;115:37-45
Paper-based microreactor array for rapid screening of cell signaling cascades.
Huang CH, Lei KF, Tsang NM
Lab on a chip 2016 Aug 7;16(15):2911-20
Lab on a chip 2016 Aug 7;16(15):2911-20
Inhibitive effects of 15-deoxy-Δ(12),(14)-prostaglandin J2 on hepatoma-cell proliferation through reactive oxygen species-mediated apoptosis.
Chen K, Dai W, Wang F, Xia Y, Li J, Li S, Liu T, Zhang R, Wang J, Lu W, Zhou Y, Yin Q, Zheng Y, Abudumijiti H, Chen R, Lu J, Zhou Y, Guo C
OncoTargets and therapy 2015;8:3585-93
OncoTargets and therapy 2015;8:3585-93
Necrostatin-1 reduces intestinal inflammation and colitis-associated tumorigenesis in mice.
Liu ZY, Wu B, Guo YS, Zhou YH, Fu ZG, Xu BQ, Li JH, Jing L, Jiang JL, Tang J, Chen ZN
American journal of cancer research 2015;5(10):3174-85
American journal of cancer research 2015;5(10):3174-85
RhNRG-1β Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway.
Gu A, Jie Y, Sun L, Zhao S, E M, You Q
PloS one 2015;10(9):e0137337
PloS one 2015;10(9):e0137337
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.
Li J, Wang F, Xia Y, Dai W, Chen K, Li S, Liu T, Zheng Y, Wang J, Lu W, Zhou Y, Yin Q, Lu J, Zhou Y, Guo C
Marine drugs 2015 May 27;13(6):3368-87
Marine drugs 2015 May 27;13(6):3368-87
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Xu D, Su C, Song X, Shi Q, Fu J, Hu L, Xia X, Song E, Song Y
Chemical research in toxicology 2015 Jun 15;28(6):1326-37
Chemical research in toxicology 2015 Jun 15;28(6):1326-37
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Su C, Xia X, Shi Q, Song X, Fu J, Xiao C, Chen H, Lu B, Sun Z, Wu S, Yang S, Li X, Ye X, Song E, Song Y
Journal of agricultural and food chemistry 2015 Jun 10;63(22):5468-75
Journal of agricultural and food chemistry 2015 Jun 10;63(22):5468-75
Effect of Fructus Ligustri Lucidi on osteoblastic like cell-line MC3T3-E1.
Li Q, Fan YS, Gao ZQ, Fan K, Liu ZJ
Journal of ethnopharmacology 2015 Jul 21;170:88-95
Journal of ethnopharmacology 2015 Jul 21;170:88-95
Sialic acid rescues repurified lipopolysaccharide-induced acute renal failure via inhibiting TLR4/PKC/gp91-mediated endoplasmic reticulum stress, apoptosis, autophagy, and pyroptosis signaling.
Yang CC, Yao CA, Yang JC, Chien CT
Toxicological sciences : an official journal of the Society of Toxicology 2014 Sep;141(1):155-65
Toxicological sciences : an official journal of the Society of Toxicology 2014 Sep;141(1):155-65
Inhibition of TROY promotes OPC differentiation and increases therapeutic efficacy of OPC graft for spinal cord injury.
Sun L, Liu S, Sun Q, Li Z, Xu F, Hou C, Harada T, Chu M, Xu K, Feng X, Duan Y, Zhang Y, Wu S
Stem cells and development 2014 Sep 1;23(17):2104-18
Stem cells and development 2014 Sep 1;23(17):2104-18
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis.
Wu J, Huang Z, Ren J, Zhang Z, He P, Li Y, Ma J, Chen W, Zhang Y, Zhou X, Yang Z, Wu SQ, Chen L, Han J
Cell research 2013 Aug;23(8):994-1006
Cell research 2013 Aug;23(8):994-1006
Induction of apoptosis by sinulariolide from soft coral through mitochondrial-related and p38MAPK pathways on human bladder carcinoma cells.
Neoh CA, Wang RY, Din ZH, Su JH, Chen YK, Tsai FJ, Weng SH, Wu YJ
Marine drugs 2012 Dec 18;10(12):2893-911
Marine drugs 2012 Dec 18;10(12):2893-911
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The JNK antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human JNK. This antibody recognizes human, mouse antigen. The JNK antibody has been validated for the following applications: ELISA, WB analysis.
