Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Other assay [1]
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Validation data
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- Product number
- PAB8112 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB8112, RRID:AB_1713442
- Product name
- MAPK8 (phospho T183) polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of MAPK8.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activation.
A JNK-dependent pathway is required for TNFalpha-induced apoptosis.
Inhibition of arachidonate 5-lipoxygenase triggers prostate cancer cell death through rapid activation of c-Jun N-terminal kinase.
Luo W, Ng WW, Jin LH, Ye Z, Han J, Lin SC
The Journal of biological chemistry 2003 Sep 26;278(39):37451-8
The Journal of biological chemistry 2003 Sep 26;278(39):37451-8
A JNK-dependent pathway is required for TNFalpha-induced apoptosis.
Deng Y, Ren X, Yang L, Lin Y, Wu X
Cell 2003 Oct 3;115(1):61-70
Cell 2003 Oct 3;115(1):61-70
Inhibition of arachidonate 5-lipoxygenase triggers prostate cancer cell death through rapid activation of c-Jun N-terminal kinase.
Ghosh J
Biochemical and biophysical research communications 2003 Jul 25;307(2):342-9
Biochemical and biophysical research communications 2003 Jul 25;307(2):342-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
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- Experimental details
- Dot blot analysis of MAPK8 (phospho T183) polyclonal antibody (Cat # PAB8112) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 ug/mL.
- Validation comment
- Dot Blot (Peptide)