Antibody data
- Antibody Data
- Antigen structure
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- Product number
- 633102 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#633102, RRID:AB_2140572
- Product name
- Purified anti-JNK1
- Antibody type
- Polyclonal
- Antigen
- Peptide mapping to the carboxy terminus of human JNK1
- Description
- The MAPK family includes several subgroups encompassing the extracellular signal-regulated kinase (ERK) family, the p38 Map kinase family, and c-Jun NH2-terminal kinase (JNK) family. JNK kinase group includes 3 members, JNK1, JNK2, and JNK3. JNK kinases are phosphorylated in response to various activations by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulate AP-1 transcriptional activity. JNK kinases are characterized by requirement for dual phosphorylation at a T-P-Y motif for enzymatic activation. The Poly6331 antibody has been shown to be useful for western blotting, immunoprecipitation, and immunohistochemistry of human, mouse, and rat JNK1 p46 and JNK1 p54 protein.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 500 µl
- Storage
- The antibody solution should be stored undiluted at 4°C. DO NOT FREEZE.
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