Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 360406 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#360406, RRID:AB_2562626
- Product name
- APC anti-human CD213a1 (IL-13Ra1)
- Antibody type
- Monoclonal
- Antigen
- Recombinant extracellular domain of human IL-13 receptor α1 chain
- Description
- CD213α1, also known as IL-13Rα1, is a subunit of the IL-13R complex. It can heterodimerize with IL-4R and bind IL-13 with high affinity. IL-13Rα1 by itself binds IL-13 with low affinity compared to IL-13Rα2. It is a 48.7 kD, single pass type I membrane protein. It is expressed at low levels on myeloid cells and on activated T and B cells and Th17 cells. It interacts with TYK2 and may lead to activation of JAK1, STAT3, and STAT6 that is induced by IL-13 and IL-4. It has been implicated to have a role in asthma and allergic responses.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Antibody clone number
- SS12B
- Vial size
- 100 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- IL-13Rα1 transfected Burkitt's lymphoma cell line (DND-39) was stained with IL-13Rα1 (clone SS12B) APC (filled histogram), or mouse IgG1, κ APC isotype control (open histogram).
- Conjugate
- Red dye