MAB5661

antibody from R&D Systems

Targeting: NRP1 CD304, NRP, VEGF165R

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

MAB5661

Provider

R&D Systems

Product name

Rat Neuropilin-1 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects rat Neuropilin-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant rat Neuropilin-2 is observed.

Reactivity

Rat

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

Q9QWJ9


Isotype

IgG

Antibody clone number

130604

Vial size

500 ug

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Neuropilin-1 is a receptor for extracellular miRNA and AGO2/miRNA complexes and mediates the internalization of miRNAs that modulate cell function.

Prud'homme GJ, Glinka Y, Lichner Z, Yousef GM
Oncotarget 2016 Oct 18;7(42):68057-68071

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Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme.

Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A
Development (Cambridge, England) 2014 Sep;141(17):3420-30

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Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor.

Acevedo LM, Barillas S, Weis SM, Göthert JR, Cheresh DA
Blood 2008 Mar 1;111(5):2674-80