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- Antigen structure
- References [7]
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- Product number
- BAF566 - Provider product page
- Provider
- R&D Systems
- Product name
- Rat Neuropilin-1 Biotinylated Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects rat Neuropilin-1 extracellular domain in Western blots. In this format, less than 1% cross-reactivity with recombinant rat Neuropilin-2 is observed.
- Reactivity
- Rat
- Host
- Goat
- Conjugate
- Biotin
- Antigen sequence
Q9QWJ9- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Compartmentalized gut lymph node drainage dictates adaptive immune responses.
Reciprocal Expression of IL-35 and IL-10 Defines Two Distinct Effector Treg Subsets that Are Required for Maintenance of Immune Tolerance.
Activation and Functional Specialization of Regulatory T Cells Lead to the Generation of Foxp3 Instability.
Tr1 Cells, but Not Foxp3+ Regulatory T Cells, Suppress NLRP3 Inflammasome Activation via an IL-10-Dependent Mechanism.
ADAM metalloproteases promote a developmental switch in responsiveness to the axonal repellant Sema3A.
Transient Treg-cell depletion in adult mice results in persistent self-reactive CD4(+) T-cell responses.
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells.
Esterházy D, Canesso MCC, Mesin L, Muller PA, de Castro TBR, Lockhart A, ElJalby M, Faria AMC, Mucida D
Nature 2019 May;569(7754):126-130
Nature 2019 May;569(7754):126-130
Reciprocal Expression of IL-35 and IL-10 Defines Two Distinct Effector Treg Subsets that Are Required for Maintenance of Immune Tolerance.
Wei X, Zhang J, Gu Q, Huang M, Zhang W, Guo J, Zhou X
Cell reports 2017 Nov 14;21(7):1853-1869
Cell reports 2017 Nov 14;21(7):1853-1869
Activation and Functional Specialization of Regulatory T Cells Lead to the Generation of Foxp3 Instability.
Zhang Z, Zhang W, Guo J, Gu Q, Zhu X, Zhou X
Journal of immunology (Baltimore, Md. : 1950) 2017 Apr 1;198(7):2612-2625
Journal of immunology (Baltimore, Md. : 1950) 2017 Apr 1;198(7):2612-2625
Tr1 Cells, but Not Foxp3+ Regulatory T Cells, Suppress NLRP3 Inflammasome Activation via an IL-10-Dependent Mechanism.
Yao Y, Vent-Schmidt J, McGeough MD, Wong M, Hoffman HM, Steiner TS, Levings MK
Journal of immunology (Baltimore, Md. : 1950) 2015 Jul 15;195(2):488-97
Journal of immunology (Baltimore, Md. : 1950) 2015 Jul 15;195(2):488-97
ADAM metalloproteases promote a developmental switch in responsiveness to the axonal repellant Sema3A.
Romi E, Gokhman I, Wong E, Antonovsky N, Ludwig A, Sagi I, Saftig P, Tessier-Lavigne M, Yaron A
Nature communications 2014 Jun 5;5:4058
Nature communications 2014 Jun 5;5:4058
Transient Treg-cell depletion in adult mice results in persistent self-reactive CD4(+) T-cell responses.
Nyström SN, Bourges D, Garry S, Ross EM, van Driel IR, Gleeson PA
European journal of immunology 2014 Dec;44(12):3621-31
European journal of immunology 2014 Dec;44(12):3621-31
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells.
Weiss JM, Bilate AM, Gobert M, Ding Y, Curotto de Lafaille MA, Parkhurst CN, Xiong H, Dolpady J, Frey AB, Ruocco MG, Yang Y, Floess S, Huehn J, Oh S, Li MO, Niec RE, Rudensky AY, Dustin ML, Littman DR, Lafaille JJ
The Journal of experimental medicine 2012 Sep 24;209(10):1723-42, S1
The Journal of experimental medicine 2012 Sep 24;209(10):1723-42, S1
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