CABT-B12289

antibody from Creative Diagnostics

Targeting: NRP1 CD304, NRP, VEGF165R

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-B12289

Provider

Creative Diagnostics

Product name

Mouse anti-Human NRP1 monoclonal antibody, clone BE6-28G7

Antibody type

Monoclonal

Description

It recognozes the human CD304 (BDCA-4) antigen. Like CD303 (BDCA-2), the CD304 (BDCA-4) antigen is specifically expressed on human plasmacytoid dendritic cells in blood and bone marrow. Unlike CD303 (BDCA-2), expression of CD304 (BDCA-4) is up-regulated on plasmacytoid dendritic cells and induced on myeloid cells upon culturing. In inflamed tonsils, CD304 (BDCA-4) expression, apart from plasmacytoid dendritic cells, is also detected primarily on follicular B helper memory T cells. CD304 (BDCA-4) is identical to neuropilin-1 (NP-1), a neuronal receptor, which is known to be expressed on numerous nonhematopoietic cell types, including neurons, endothelial, and tumor cells. CD1a+ dendritic cells generated ex vivo from monocytes or hematopoietic precursor cells are CD304 (BDCA-4)+ but CD303 (BDCA-2)\u2013 .

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

BE6-28G7

Vial size

100 _g in 100 _L

Storage

Store protected from light at 2ÿ8 °C. Do not freeze.