M00340

antibody from Boster Biological Technology
Targeting: NFATC1 NF-ATC, NFAT2, NFATc
Provider product page for M00340
Western blot
Immunocytochemistry

Antibody data

Product number
M00340 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-NFAT2 NFATC1 Rabbit Monoclonal Antibody
Antibody type
Monoclonal
Description
Monoclonal antibody for NFAT2/NFATC1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IF, ICC, WB. Reactive species: Human NFAT2/NFATC1 information: Molecular Weight: 101243 MW; Subcellular Localization: Cytoplasm . Nucleus . Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription; Tissue Specificity: Expressed in thymus, peripheral leukocytes as T-cells and spleen. Isoforms A are preferentially expressed in effector T-cells (thymus and peripheral leukocytes) whereas isoforms B and isoforms C are preferentially expressed in naive T- cells (spleen). Isoforms B are expressed in naive T-cells after first antigen exposure and isoforms A are expressed in effector T- cells after second antigen exposure. Isoforms IA are widely expressed but not detected in liver nor pancreas, neural expression is strongest in corp
Reactivity
Human
Host
Rabbit
Antibody clone number
ABDA-14
Vial size
100ug/vial
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage
At -20°C for one year. Avoid repeated freezing and thawing.
NFATC1 protein structure - M00340 shown in red.