M00340

antibody from Boster Biological Technology

Targeting: NFATC1 NF-ATC, NFAT2, NFATc

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

M00340

Provider

Boster Biological Technology

Product name

Anti-NFAT2 NFATC1 Rabbit Monoclonal Antibody

Antibody type

Monoclonal

Description

Monoclonal antibody for NFAT2/NFATC1 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IF, ICC, WB. Reactive species: Human NFAT2/NFATC1 information: Molecular Weight: 101243 MW; Subcellular Localization: Cytoplasm . Nucleus . Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription; Tissue Specificity: Expressed in thymus, peripheral leukocytes as T-cells and spleen. Isoforms A are preferentially expressed in effector T-cells (thymus and peripheral leukocytes) whereas isoforms B and isoforms C are preferentially expressed in naive T- cells (spleen). Isoforms B are expressed in naive T-cells after first antigen exposure and isoforms A are expressed in effector T- cells after second antigen exposure. Isoforms IA are widely expressed but not detected in liver nor pancreas, neural expression is strongest in corp

Reactivity

Human

Host

Rabbit

Antibody clone number

ABDA-14

Vial size

100ug/vial

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Storage

At -20°C for one year. Avoid repeated freezing and thawing.