Antibody data
- Antibody Data
- Antigen structure
- References [46]
- Comments [0]
- Validations [0]
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- Product number
- 66963-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- NFATC1 antibody
- Antibody type
- Monoclonal
- Description
- NFATC1 antibody (Cat. #66963-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1E1B10
- Vial size
- 20ul, 150ul
Submitted references Yunnan Baiyao Might Mitigate Periodontitis Bone Destruction by Inhibiting Autophagy and Promoting Osteoblast Differentiation in vivo, ex vivo and in vitro.
Forskolin is an effective therapeutic small molecule for the treatment of hypertrophic cardiomyopathy through ADCY6/cAMP/PKA pathway.
Mitigation of inflammatory bowel disease-related osteoporosis by oxyberberine: Insights into the RANKL/NF-κB signaling pathway.
D-alanine suppressed osteoclastogenesis derived from bone marrow macrophages and downregulated ERK/p38 signalling pathways.
StemRegenin 1 attenuates the RANKL-induced osteoclastogenesis via inhibiting AhR-c-src-NF-κB/p-ERK MAPK-NFATc1 signaling pathway.
C5a-C5aR1 axis controls mitochondrial fission to promote podocyte injury in lupus nephritis.
FPR3 reprograms glycolytic metabolism and stemness in gastric cancer via calcium-NFATc1 pathway.
MEDAG expression in vitro and paeoniflorin alleviates bone loss by regulating the MEDAG/AMPK/PPARγ signaling pathway in vivo.
Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasis.
Targeting CD38/ ADP-ribosyl cyclase as a novel therapeutic strategy for identification of three potent agonists for leukopenia treatment.
Farrerol suppresses osteoclast differentiation and postmenopausal osteoporosis by inhibiting the nuclear factor kappa B signaling pathway.
Yunnan Baiyao Inhibits Periodontitis by Suppressing the Autophagic Flux.
A parathyroid hormone related supramolecular peptide for multi-functionalized osteoregeneration.
The mechanism of metformin combined with total flavonoids of Rhizoma Drynariae on ovariectomy-induced osteoporotic rats.
Glycogen synthase kinase 3 controls T-cell exhaustion by regulating NFAT activation.
KCTD4 interacts with CLIC1 to disrupt calcium homeostasis and promote metastasis in esophageal cancer.
Dietary Taurine Supplementation Improves the Meat Quality, Muscle Fiber Type, and Mitochondrial Function of Finishing Pigs.
Anti-resorption role of low-intensity pulsed ultrasound (LIPUS) during large-scale bone reconstruction using porous titanium alloy scaffolds through inhibiting osteoclast differentiation.
Metastatic prostate cancer-derived extracellular vesicles facilitate osteoclastogenesis by transferring the CDCP1 protein.
An innovative immunotherapeutic strategy for rheumatoid arthritis: Selectively suppressing angiogenesis and osteoclast differentiation by fully human antibody targeting thymocyte antigen-1.
FTO-dependent m(6)A regulates muscle fiber remodeling in an NFATC1-YTHDF2 dependent manner.
Disruption of RCAN1.4 expression mediated by YY1/HDAC2 modulates chronic renal allograft interstitial fibrosis.
The role of NPY2R/NFATc1/DYRK1A regulatory axis in sebaceous glands for sebum synthesis.
Taurine promotes muscle fiber type transformation through CaN/NFATc1 signaling in porcine myoblasts.
CRTAC1 enhances the chemosensitivity of non-small cell lung cancer to cisplatin by eliciting RyR-mediated calcium release and inhibiting Akt1 expression.
Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.
The Dibenzyl Isoquinoline Alkaloid Berbamine Ameliorates Osteoporosis by Inhibiting Bone Resorption.
Baohuoside I Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.
A 3D-printed molybdenum-containing scaffold exerts dual pro-osteogenic and anti-osteoclastogenic effects to facilitate alveolar bone repair.
Complete abrogation of key osteoclast markers with a membrane-anchored tissue inhibitor of metalloproteinase : a novel approach in the prevention of osteoclastogenesis.
Cinacalcet Improves Bone Parameters Through Regulation of Osteoclast Endoplasmic Reticulum Stress, Autophagy, and Apoptotic Pathways in Chronic Kidney Disease-Mineral and Bone Disorder.
Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity.
TGF-β1 Induces Immune Escape by Enhancing PD-1 and CTLA-4 Expression on T Lymphocytes in Hepatocellular Carcinoma.
TRPC3 promotes tumorigenesis of gastric cancer via the CNB2/GSK3β/NFATc2 signaling pathway.
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
Regulator of calcineurin 1 gene isoform 4 in pancreatic ductal adenocarcinoma regulates the progression of tumor cells.
4-Hexylresorcinol inhibits osteoclastogenesis by suppressing the NF-κB signaling pathway and reverses bone loss in ovariectomized mice.
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis.
Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling.
Calcium Channel Blocker Nifedipine Suppresses Colorectal Cancer Progression and Immune Escape by Preventing NFAT2 Nuclear Translocation.
Discovery of Small-Molecule Inhibitors of Receptor Activator of Nuclear Factor-κB Ligand with a Superior Therapeutic Index.
IL-33/ST2/IL-9/IL-9R signaling disrupts ocular surface barrier in allergic inflammation.
miR-142-5p promotes the osteoclast differentiation of bone marrow-derived macrophages via PTEN/PI3K/AKT/FoxO1 pathway.
Interactions between β-cyclodextrin and tea catechins, and potential anti-osteoclastogenesis activity of the (-)-epigallocatechin-3-gallate-β-cyclodextrin complex.
Liu W, Li Y, An Y, Zhao R, Wei C, Ren X, He H
Journal of inflammation research 2024;17:2271-2284
Journal of inflammation research 2024;17:2271-2284
Forskolin is an effective therapeutic small molecule for the treatment of hypertrophic cardiomyopathy through ADCY6/cAMP/PKA pathway.
Wang W, Xue Y, Li D, Shao C, Wu K, Sun N, Chen Q
European journal of pharmacology 2024 Sep 5;978:176770
European journal of pharmacology 2024 Sep 5;978:176770
Mitigation of inflammatory bowel disease-related osteoporosis by oxyberberine: Insights into the RANKL/NF-κB signaling pathway.
Chen T, Ai G, Liang G, Zeng L, Zhao D, Liu J, Dou Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116523
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116523
D-alanine suppressed osteoclastogenesis derived from bone marrow macrophages and downregulated ERK/p38 signalling pathways.
Chang X, Deng J, Zhou F, Geng Z, Li X, Wang S
Archives of oral biology 2024 May;161:105912
Archives of oral biology 2024 May;161:105912
StemRegenin 1 attenuates the RANKL-induced osteoclastogenesis via inhibiting AhR-c-src-NF-κB/p-ERK MAPK-NFATc1 signaling pathway.
Zhou S, Li J, Ying T, Wang Y, Wang Q, Li X, Zhao F
iScience 2024 May 17;27(5):109682
iScience 2024 May 17;27(5):109682
C5a-C5aR1 axis controls mitochondrial fission to promote podocyte injury in lupus nephritis.
Ye B, Chen B, Guo C, Xiong N, Huang Y, Li M, Lai Y, Li J, Zhou M, Wang S, Wang S, Yang N, Zhang H
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1540-1560
Molecular therapy : the journal of the American Society of Gene Therapy 2024 May 1;32(5):1540-1560
FPR3 reprograms glycolytic metabolism and stemness in gastric cancer via calcium-NFATc1 pathway.
Wang L, Mao X, Yu X, Su J, Li Z, Chen Z, Ren Y, Huang H, Wang W, Zhao C, Hu Y
Cancer letters 2024 Jul 1;593:216841
Cancer letters 2024 Jul 1;593:216841
MEDAG expression in vitro and paeoniflorin alleviates bone loss by regulating the MEDAG/AMPK/PPARγ signaling pathway in vivo.
Liu H, Chang Z, Liu S, Zhu R, Ma J, Lu X, Li L, Zhang Z
Heliyon 2024 Jan 15;10(1):e24241
Heliyon 2024 Jan 15;10(1):e24241
Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasis.
Wu DZ, Zhu GZ, Zhao K, Gao JW, Cai GX, Li HZ, Huang YS, Tu C, Zhuang JS, Huang ZW, Zhong ZM
Molecular medicine (Cambridge, Mass.) 2024 Jan 12;30(1):10
Molecular medicine (Cambridge, Mass.) 2024 Jan 12;30(1):10
Targeting CD38/ ADP-ribosyl cyclase as a novel therapeutic strategy for identification of three potent agonists for leukopenia treatment.
Liu Y, Zhang L, Wang L, Tang X, Wan S, Huang Q, Ran M, Shen H, Yang Y, Chiampanichayakul S, Tima S, Anuchapreeda S, Wu J
Pharmacological research 2024 Feb;200:107068
Pharmacological research 2024 Feb;200:107068
Farrerol suppresses osteoclast differentiation and postmenopausal osteoporosis by inhibiting the nuclear factor kappa B signaling pathway.
Lu W, Qi G, Yang X, Li D, Chen W, Zeng Q, Jiang Z
Journal of pharmacological sciences 2024 Feb;154(2):113-126
Journal of pharmacological sciences 2024 Feb;154(2):113-126
Yunnan Baiyao Inhibits Periodontitis by Suppressing the Autophagic Flux.
Li Y, Liu W, Zhao R, An Y, Zhang M, Ren X, He H
International dental journal 2024 Apr;74(2):284-293
International dental journal 2024 Apr;74(2):284-293
A parathyroid hormone related supramolecular peptide for multi-functionalized osteoregeneration.
Hao Z, Feng Q, Wang Y, Wang Y, Li H, Hu Y, Chen T, Wang J, Chen R, Lv X, Yang Z, Chen J, Guo X, Li J
Bioactive materials 2024 Apr;34:181-203
Bioactive materials 2024 Apr;34:181-203
The mechanism of metformin combined with total flavonoids of Rhizoma Drynariae on ovariectomy-induced osteoporotic rats.
Jiang N, Jin H, Yang K, Zhang Z, Xu W, Chen X, Zhang Z, Xu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115181
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115181
Glycogen synthase kinase 3 controls T-cell exhaustion by regulating NFAT activation.
Fu Y, Wang J, Liu C, Liao K, Gao X, Tang R, Fan B, Hong Y, Xiao N, Xiao C, Liu WH
Cellular & molecular immunology 2023 Oct;20(10):1127-1139
Cellular & molecular immunology 2023 Oct;20(10):1127-1139
KCTD4 interacts with CLIC1 to disrupt calcium homeostasis and promote metastasis in esophageal cancer.
Zheng C, Yu X, Xu T, Liu Z, Jiang Z, Xu J, Yang J, Zhang G, He Y, Yang H, Shi X, Li Z, Liu J, Xu WW
Acta pharmaceutica Sinica. B 2023 Oct;13(10):4217-4233
Acta pharmaceutica Sinica. B 2023 Oct;13(10):4217-4233
Dietary Taurine Supplementation Improves the Meat Quality, Muscle Fiber Type, and Mitochondrial Function of Finishing Pigs.
An W, Huang Z, Mao Z, Qiao T, Jia G, Zhao H, Liu G, Chen X
Journal of agricultural and food chemistry 2023 Oct 18;71(41):15331-15340
Journal of agricultural and food chemistry 2023 Oct 18;71(41):15331-15340
Anti-resorption role of low-intensity pulsed ultrasound (LIPUS) during large-scale bone reconstruction using porous titanium alloy scaffolds through inhibiting osteoclast differentiation.
Luo L, Cao H, Zhou L, Zhang G, Wu L
Biomaterials advances 2023 Nov;154:213634
Biomaterials advances 2023 Nov;154:213634
Metastatic prostate cancer-derived extracellular vesicles facilitate osteoclastogenesis by transferring the CDCP1 protein.
Urabe F, Kosaka N, Yamamoto Y, Ito K, Otsuka K, Soekmadji C, Egawa S, Kimura T, Ochiya T
Journal of extracellular vesicles 2023 Mar;12(3):e12312
Journal of extracellular vesicles 2023 Mar;12(3):e12312
An innovative immunotherapeutic strategy for rheumatoid arthritis: Selectively suppressing angiogenesis and osteoclast differentiation by fully human antibody targeting thymocyte antigen-1.
Hu X, Li M, Zhang Y, Sang K, Zhang Y, Li W, Liu B, Wan L, Du B, Qian J, Meng F, Fu Y, Dai M, Gao G, Ye H
Experimental cell research 2023 Mar 1;424(1):113490
Experimental cell research 2023 Mar 1;424(1):113490
FTO-dependent m(6)A regulates muscle fiber remodeling in an NFATC1-YTHDF2 dependent manner.
Wang W, Du X, Luo M, Yang N
Clinical epigenetics 2023 Jul 5;15(1):109
Clinical epigenetics 2023 Jul 5;15(1):109
Disruption of RCAN1.4 expression mediated by YY1/HDAC2 modulates chronic renal allograft interstitial fibrosis.
Zhang J, Zhang Y, Feng D, Zhou H, Gui Z, Zheng M, Hang Z, Gu M, Tan R
Cell death discovery 2023 Jul 28;9(1):271
Cell death discovery 2023 Jul 28;9(1):271
The role of NPY2R/NFATc1/DYRK1A regulatory axis in sebaceous glands for sebum synthesis.
Yang T, Hei R, Li X, Ma T, Shen Y, Liu C, He W, Zhu L, Gu Y, Hu Y, Wei W, Shen Y
Cellular & molecular biology letters 2023 Jul 27;28(1):60
Cellular & molecular biology letters 2023 Jul 27;28(1):60
Taurine promotes muscle fiber type transformation through CaN/NFATc1 signaling in porcine myoblasts.
An W, Huang Z, Mao Z, Jia G, Zhao H, Liu G, Chen X
Journal of cellular physiology 2023 Dec;238(12):2879-2887
Journal of cellular physiology 2023 Dec;238(12):2879-2887
CRTAC1 enhances the chemosensitivity of non-small cell lung cancer to cisplatin by eliciting RyR-mediated calcium release and inhibiting Akt1 expression.
Jin Z, Zhao L, Chang Y, Jin R, Hu F, Wu S, Xue Z, Ma Y, Chen C, Zheng M, Chang Y, Jin H, Xie Q, Huang C, Huang H
Cell death & disease 2023 Aug 26;14(8):563
Cell death & disease 2023 Aug 26;14(8):563
Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.
Chen T, Zhang X, Ding X, Feng J, Zhang X, Xie D, Wang X
Molecular oncology 2023 Apr;17(4):695-709
Molecular oncology 2023 Apr;17(4):695-709
The Dibenzyl Isoquinoline Alkaloid Berbamine Ameliorates Osteoporosis by Inhibiting Bone Resorption.
Zhang C, Zhong Z, Sang W, Ghorbani F, Ghalandari B, Mohamadali M, Irani S, Qian Z, Yi C, Yu B
Frontiers in endocrinology 2022;13:885507
Frontiers in endocrinology 2022;13:885507
Baohuoside I Inhibits Osteoclastogenesis and Protects Against Ovariectomy-Induced Bone Loss.
Ma M, Fan AY, Liu Z, Yang LQ, Huang JM, Pang ZY, Yin F
Frontiers in pharmacology 2022;13:874952
Frontiers in pharmacology 2022;13:874952
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.
Luo S, Li Y, Li S, Jiang R, Deng F, Liu G, Zhang J
Frontiers in physiology 2022;13:856427
Frontiers in physiology 2022;13:856427
A 3D-printed molybdenum-containing scaffold exerts dual pro-osteogenic and anti-osteoclastogenic effects to facilitate alveolar bone repair.
Tian B, Li X, Zhang J, Zhang M, Gan D, Deng D, Sun L, He X, Wu C, Chen F
International journal of oral science 2022 Sep 5;14(1):45
International journal of oral science 2022 Sep 5;14(1):45
Complete abrogation of key osteoclast markers with a membrane-anchored tissue inhibitor of metalloproteinase : a novel approach in the prevention of osteoclastogenesis.
Zhang Y, Jiang B, Zhang P, Chiu SK, Lee MH
Bone & joint research 2022 Nov;11(11):763-776
Bone & joint research 2022 Nov;11(11):763-776
Cinacalcet Improves Bone Parameters Through Regulation of Osteoclast Endoplasmic Reticulum Stress, Autophagy, and Apoptotic Pathways in Chronic Kidney Disease-Mineral and Bone Disorder.
Chiu HW, Hou YC, Lu CL, Lu KC, Liu WC, Shyu JF, Chang JF, Zheng CM
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2022 Feb;37(2):215-225
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2022 Feb;37(2):215-225
Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity.
Huang JM, Wang CZ, Lu SY, Wang Z, Yan ZQ
Drug design, development and therapy 2021;15:4811-4825
Drug design, development and therapy 2021;15:4811-4825
TGF-β1 Induces Immune Escape by Enhancing PD-1 and CTLA-4 Expression on T Lymphocytes in Hepatocellular Carcinoma.
Bao S, Jiang X, Jin S, Tu P, Lu J
Frontiers in oncology 2021;11:694145
Frontiers in oncology 2021;11:694145
TRPC3 promotes tumorigenesis of gastric cancer via the CNB2/GSK3β/NFATc2 signaling pathway.
Lin DC, Zheng SY, Zhang ZG, Luo JH, Zhu ZL, Li L, Chen LS, Lin X, Sham JSK, Lin MJ, Zhou RX
Cancer letters 2021 Oct 28;519:211-225
Cancer letters 2021 Oct 28;519:211-225
Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition.
Jia X, Zhu H, Li G, Lan M, Li X, Huang M, Xu W, Wu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111321
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May;137:111321
Regulator of calcineurin 1 gene isoform 4 in pancreatic ductal adenocarcinoma regulates the progression of tumor cells.
Lao M, Zhang X, Ma T, Xu J, Yang H, Duan Y, Ying H, Zhang X, Guo C, Qiu J, Bai X, Liang T
Oncogene 2021 Apr;40(17):3136-3151
Oncogene 2021 Apr;40(17):3136-3151
4-Hexylresorcinol inhibits osteoclastogenesis by suppressing the NF-κB signaling pathway and reverses bone loss in ovariectomized mice.
Yi W, Liu T, Gao X, Xie Y, Liu M
Experimental and therapeutic medicine 2021 Apr;21(4):354
Experimental and therapeutic medicine 2021 Apr;21(4):354
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Qi D, Liu H, Sun X, Luo D, Zhu M, Tao T, Gao C, Zhou C, Zhou W, Xiao J
Frontiers in pharmacology 2020;11:621110
Frontiers in pharmacology 2020;11:621110
Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis.
Qian Z, Zhong Z, Ni S, Li D, Zhang F, Zhou Y, Kang Z, Qian J, Yu B
Journal of cellular and molecular medicine 2020 Sep;24(17):10112-10127
Journal of cellular and molecular medicine 2020 Sep;24(17):10112-10127
Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling.
Ni S, Qian Z, Yuan Y, Li D, Zhong Z, Ghorbani F, Zhang X, Zhang F, Zhang Z, Liu Z, Yu B
Cell proliferation 2020 Oct;53(10):e12882
Cell proliferation 2020 Oct;53(10):e12882
Calcium Channel Blocker Nifedipine Suppresses Colorectal Cancer Progression and Immune Escape by Preventing NFAT2 Nuclear Translocation.
Wu L, Lin W, Liao Q, Wang H, Lin C, Tang L, Lian W, Chen Z, Li K, Xu L, Zhou R, Ding Y, Zhao L
Cell reports 2020 Oct 27;33(4):108327
Cell reports 2020 Oct 27;33(4):108327
Discovery of Small-Molecule Inhibitors of Receptor Activator of Nuclear Factor-κB Ligand with a Superior Therapeutic Index.
Rinotas V, Papakyriakou A, Violitzi F, Papaneophytou C, Ouzouni MD, Alexiou P, Strongilos A, Couladouros E, Kontopidis G, Eliopoulos E, Douni E
Journal of medicinal chemistry 2020 Oct 22;63(20):12043-12059
Journal of medicinal chemistry 2020 Oct 22;63(20):12043-12059
IL-33/ST2/IL-9/IL-9R signaling disrupts ocular surface barrier in allergic inflammation.
Hu J, Gao N, Zhang Y, Chen X, Li J, Bian F, Chi W, Liu Z, de Paiva CS, Pflugfelder SC, Li DQ
Mucosal immunology 2020 Nov;13(6):919-930
Mucosal immunology 2020 Nov;13(6):919-930
miR-142-5p promotes the osteoclast differentiation of bone marrow-derived macrophages via PTEN/PI3K/AKT/FoxO1 pathway.
Lou Z, Peng Z, Wang B, Li X, Li X, Zhang X
Journal of bone and mineral metabolism 2019 Sep;37(5):815-824
Journal of bone and mineral metabolism 2019 Sep;37(5):815-824
Interactions between β-cyclodextrin and tea catechins, and potential anti-osteoclastogenesis activity of the (-)-epigallocatechin-3-gallate-β-cyclodextrin complex.
Xu H, Liu T, Xu J, Li J, Chen F, Xiang Z, Huang Y, Zhang D, Hu L, Zhang B, Zi C, Wang X, Sheng J
RSC advances 2019 Sep 3;9(48):28006-28018
RSC advances 2019 Sep 3;9(48):28006-28018
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